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489 results for “cell plasticity”
A 3D printed plastic frame deeply impacts yeast cell growth
<p>Solid State Fermentation (SSF) processes have been explored for yeast growth and protein and metabolites production. However, most of these processes lack standardization. In this work, we present a polylactic acid (PLA) 3D printed matrix that dramatically enhances yeast growth when embedded in liquid media compared to equivalent static cultures, and changes yeast expression patterns at the proteome level. Moreover, differences in sugar assimilation and ethanol production, as the main product of alcoholic fermentation, are observed. Our results suggest that these matrixes may be useful for a vast range of biotechnological applications based on yeast fermentation. Here we submit the proteomic data of this paper.</p>
Data from: Plastic and evolutionary responses of cell size and number to larval malnutrition in Drosophila melanogaster
Both development and evolution under chronic malnutrition lead to reduced adult size in Drosophila. We studied the contribution of changes in size vs. number of epidermal cells to plastic and evolutionary reduction of wing size in response to poor larval food. We used flies from six populations selected for tolerance to larval malnutrition and from six unselected control populations, raised either under standard conditions or under larval malnutrition. In the control populations, phenotypic plasticity of wing size was mediated by both cell size and cell number. In contrast, evolutionary change in wing size, which was only observed as a correlated response expressed on standard food, was mediated entirely by reduction in cell number. Plasticity of cell number had been lost in the selected populations, and cell number did not differ between the sexes despite males having smaller wings. Results of this and other experimental evolution studies are consistent with the hypothesis that alleles which increase body size through prolonged growth affect wing size mostly via cell number, whereas alleles which increase size through higher growth rate do so via cell size.
Data from: In a variable thermal environment selection favors greater plasticity of cell membranes in Drosophila melanogaster
Open the record for dataset details and reuse information.
Data from: Plastic and evolutionary responses of cell size and number to larval malnutrition in Drosophila melanogaster
Open the record for dataset details and reuse information.
KDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung Cancer.
GEO Series GSE215829. Mus musculus. 26 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A plastic EMP1⁺ to LGR5⁺ cell state conversion as a therapeutic bypass to KRAS-G12D inhibition in metastatic colorectal cancer [RNA-Seq]
GEO Series GSE303692. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
CD19 CAR immune pressure on B cell acute lymphoblastic leukemia induces myeloid lineage switch exposing inherent leukemic plasticity
GEO Series GSE83205. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Human CCR6+ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity [Spsingh-10x-TCR-plus-transcriptome-kit]
GEO Series GSE227656. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells
GEO Series GSE18737. Mus musculus. 83 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by genome tiling array.
H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium
GEO Series GSE247253. Mus musculus. 149 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Developmental plasticity of epithelial stem cells in tooth and taste bud renewal
GEO Series GSE128942. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer [Single cell RNA-seq]
GEO Series GSE279200. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing; Other.
Serine-Driven Metabolic Plasticity Drives Adaptive Resilience in Pancreatic Cancer Cells [HPAF-2]
GEO Series GSE292890. Homo sapiens. 16 samples. Type: Expression profiling by array.
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity [scRNA-seq]
GEO Series GSE121598. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
MAIT cell plasticity enables functional adaption that drives anti-bacterial immune protection
GEO Series GSE274087. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair [1]
GEO Series GSE247130. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Influence of temperature fluctuations during cryopreservation on vital parameters, plasticity, and transgene expression of placental multipotent stromal cells
GEO Series GSE85097. Homo sapiens. 10 samples. Type: Expression profiling by array.
Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity
GEO Series GSE183729. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Innate immunity and Nfkb pathway control prostate stem cell plasticity, reprogramming and tumor initiation
GEO Series GSE270189. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Chemotherapy induces cell plasticity; controlling plasticity increases therapeutic response.
GEO Series GSE229761. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.