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296 results for “diagnostic accuracy”
MiRoR2 - P2 - Use of test accuracy study design labels in NICE's diagnostic guidance
<p>Data set for the study “Use of test accuracy study design labels in NICE's diagnostic guidance”, including list of the included NICE guidance, data extraction form, extracted data with summary of results, and extraction guidance.</p> <p>Reference to associated article: Olsen M, Zhelev Z, Hunt H, Peters JL, Bossuyt PM, Hyde C. Use of test accuracy study design labels in NICE’s diagnostic guidance. Diagnostic and Prognostic Research. 2019;3:17</p>
Diagnostic Accuracy of Adrenal Imaging for Subtype Diagnosis in Primary Aldosteronism: Systematic Review and Meta-Analysis
<p>Objectives: Accurate subtype classification in primary aldosteronism (PA) is critical in assessing the optimal treatment options. This study aimed to evaluate the diagnostic accuracy of adrenal imaging for unilateral PA classification.</p> <p>Methods: Systematic searches of PubMed, EMBASE, and the Cochrane databases were performed from January 1, 2000, to February 1, 2020, for all studies that used computed tomography (CT) or magnetic resonance imaging (MRI) in determining unilateral PA and validated the results against invasive adrenal vein sampling (AVS). Summary diagnostic accuracies were assessed using a bivariate random-effects model. Subgroup analyses, meta-regression and sensitivity analysis were performed to explore the possible sources of heterogeneity.</p> <p>Result: A total of 25 studies, involving a total of 4669 subjects, were identified. The overall analysis revealed a pooled sensitivity of 68% (95% confidence interval [CI]: 61 to 74) and specificity of 57% (95% CI: 50 to 65) for CT/MRI in identifying unilateral PA. Sensitivity was higher in the contrast-enhanced (CT) group versus the traditional CT group [77% (95% CI: 66 to 85) vs. 58% (95% CI: 50 to 66)]. Subgroup analysis stratified by screening test for PA showed that the sensitivity of the aldosterone-to-renin ratio (ARR) group was higher than that of the non-ARR group [78% (95% CI: 69 to 84) vs. 66% (95% CI: 58 to 72)]. The diagnostic accuracy of PA patients aged ≤40 years was reported in 4 studies, and the overall sensitivity was 71%, with 79% specificity. Meta-regression revealed a significant impact of sample size on sensitivity and of age and study quality on specificity.</p> <p>Conclusion: CT/MRI is not a reliable alternative to invasive AVS without excellent sensitivity or specificity for correctly identifying unilateral PA. Even in young patients (≤40 years), 21% of patients would have undergone unnecessary adrenalectomy based on imaging results alone.</p>
Data from: Diagnostic accuracy of presepsin in predicting bacteremia in elderly patients admitted to the emergency department: prospective study in Japan
<p class="CxSpFirst"><span><b>Objective</b></span></p> <p class="CxSpMiddle"><span><a name="_Hlk1399924">Early detection of bacteremia in the elderly is needed in the emergency department (ED). </a></span></p> <p class="CxSpMiddle"><span><a name="_Hlk11878757"><b>Design, Setting, and Participants</b></a></span></p> <p class="CxSpMiddle"><span>Prospective study in Japan, single center trial in patients who satisfied the sepsis criteria was conducted between September 2014 and March 2016. Forty-six elderly patients aged ≥70 years were included.</span></p> <p class="CxSpMiddle"><span><b>Interventions</b></span></p> <p class="CxSpMiddle"><span>Blood sampling to evaluate C-reactive protein (CRP), procalcitonin (PCT) and presepsin plasma levels; two sets of blood sampling for bacterial cultures; and evaluations of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores were performed upon arrival at the ED. The results were compared between patients with bacteremia and those without bacteremia.</span></p> <p class="CxSpMiddle"><span><a name="_Hlk11878769"><b>Main Outcome Measure</b></a></span></p> <p class="CxSpMiddle"><span>The accuracy of detecting bacteremia</span></p> <p class="CxSpMiddle"><span><b>Results</b></span></p> <p class="CxSpMiddle"><span>The presepsin value was significantly higher in the bacteremia group than in the non-bacteremia group (866.6 ± 184.6 pg/mL vs. 639.9 ± 137.1 pg/mL, p = 0.03). The PCT and CRP did not significantly differ between the groups. The area under the receiver-operating-characteristic curve (AUC) values were not significantly different among presepsin (0.69), PCT (0.61), and CRP (0.53). Multivariate analysis showed that presepsin was independently associated with bacteremia (odds ratio, 8.84; 95% confidence interval, 0.95–81.79; p = 0.02).</span></p> <p class="CxSpMiddle"><span><b>Conclusion<a name="_Hlk1399945"></a></b></span></p> <p class="CxSpMiddle"><span>Presepsin could be a good biomarker to predict bacteremia in elderly patients with sepsis criteria admitted to the ED.</span></p>
Percussion test: description and diagnostic accuracy of a new manual test for bone marrow edema of the knee - RAW DATASET
<p>Background</p> <p>Prompt diagnosis of bone marrow lesion (BML) is difficult but critical for correct treatment. Magnetic resonance imaging is the gold standard, although expensive and time consuming. Simple and reliable clinical test for BML detection is lacking. Aim of the study is to describe a new manual clinical test called Percussion Test (PT) and to statistically determine its diagnostic accuracy in BML, compared to MRI imaging.</p> <p>Methods</p> <p>After evaluation of the inclusion and exclusion criteria, 218 consecutive patients with unilateral knee pain and age comprised between 18 and 80 years old were enrolled in our observational prospective study. Informed consent was obtained for each patient. After medical history collection, PT was performed by a single operator as described. MRI was performed in the affected knee to detect the presence of BML. Coherence in PT and MRI assessment was evaluated in each quadrant of the knee via contingency tables, as sensitivity, specificity, NPV, PPV and diagnostic accuracy were calculated.</p> <p>Results</p> <p>No correlation with a positive PT was demonstrated for the covariables gender (<em>p</em> =&thinsp;0.156), age (<em>p</em> =&thinsp;0.272) and BMI (<em>p</em> =&thinsp;0.639).</p> <p>PT showed a sensitivity ranging from 60.6 (40.6–80.6) to 79.5 (63.0–96.0) and a specificity ranging from 85.7 (80.0–91.5) to 96.0 (93.1–98.9) depending on knee quadrant. Diagnostic accuracy ranged from 81.6 (75.9–86.6) to 89.4 (84.6–93.2), and <em>p</em>-value was < 0.00001 in a chi-squared analysis for all quadrants.</p> <p>Conclusions</p> <p>PT showed sensitivity and specificity values that are comparable with other clinical tests routinely adopted in clinical practice. In the absence of other reliable clinical test, PT has the potential to become a useful bedside tool in the diagnosis and management of BMLs.</p>
Raw datasets and media accompanying the manuscript: Fused Raman spectroscopy analysis of blood and saliva delivers high accuracy for head and neck cancer diagnostics
<p>Raw datasets and media accompanying the manuscript: <strong>Fused Raman spectroscopy analysis of blood and saliva delivers high accuracy for head and neck cancer diagnostics</strong></p>
Diagnostic accuracy of Panbio™ rapid antigen test for SARS-CoV-2 in paediatric population
<p>The aim was to evaluate the accuracy of the Panbio<sup>TM</sup> Rapid Antigen Test for SARS-CoV-2 in the setting of a primary health care centre (PHC) in paedriatic population, with use of the Reverse Transcription-Polymerase Chain Reaction (RT-PCR) as gold standard.</p>
Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.
ClinicalTrials.gov study NCT06625268. IPD Sharing: NO. Countries: 1. Publications: 2.
Diagnostic Accuracy of Optical Coherence Tomography in Upper Urinary Tract Urothelial Carcinoma
ClinicalTrials.gov study NCT02326909. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Ultrasonographic Characterization of Parametrial Lesions in Deep Endometriosis: A Diagnostic-Accuracy Study (ULTRA-PARAMETRENDO III)
ClinicalTrials.gov study NCT06017531. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Diagnostic Accuracy of The Water Immersion Wrinkle Test for Small Fiber Neuropathy
ClinicalTrials.gov study NCT07255573. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.
The Accuracy of Manual BPPV Diagnostics When Using VNG Goggles.
ClinicalTrials.gov study NCT05846711. IPD Sharing: NO. Countries: 1. Publications: 3.
Diagnostic Accuracy of Seated Saline Suppression Test for Primary Aldosteronism
ClinicalTrials.gov study NCT03500120. IPD Sharing: NO. Countries: 1. Publications: 6.
Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain
ClinicalTrials.gov study NCT00855231. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Evaluation of Diagnostic Accuracy, Safety, and Cost-Effectiveness of the Non-Invasive Cardiolens FFR-CT Pro Method to Measure the Fractional Flow Reserve in Diagnostics of Chronic Coronary Syndromes V
ClinicalTrials.gov study NCT04777513. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.
Diagnostic Accuracy of Foot Length in Predicting Preterm and Low Birth Weight Using Ultrasound Dating as The Gold Standard in a Rural District of Pakistan
ClinicalTrials.gov study NCT05515211. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Diagnostic Accuracy of Bedside Ultrasound in Suspected Acute Diverticulitis
ClinicalTrials.gov study NCT03279588. IPD Sharing: NO. Countries: 1. Publications: 6.
Biopsy Protocol of Upper Gastrointestinal Subepithelial Tumors:Diagnostic Accuracy of EUS-FNB Versus Unroofing Biopsy
ClinicalTrials.gov study NCT02646241. IPD Sharing: NO. Countries: 1. Publications: 1.
Diagnostic Accuracy of Ultrasonography in Detecting Benign Radiolucent Lesions
ClinicalTrials.gov study NCT02121236. IPD Sharing: Not stated. Countries: 1. Publications: 6.
PoCUS Diagnostic Accuracy for Fecal Impaction in the Emergency Department: A Prospective Study
ClinicalTrials.gov study NCT06333106. IPD Sharing: NO. Countries: 1. Publications: 16.
Diagnostic Accuracy of Placental Thickness in Lower Uterine Segment Measured By Ultrasound in Prediction of Placenta Accreta Spectrum in Patients With Placenta Previa. A Diagnostic Test Accuracy Study
ClinicalTrials.gov study NCT05500404. IPD Sharing: NO. Countries: 1. Publications: 7.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.