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48 results for “disruptive selection”

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geo24/100

Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers

GEO Series GSE245006. Homo sapiens. 519 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Selective Disruption of Core Regulatory Transcription [single cell RNA-seq]

GEO Series GSE121107. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2019View details →
geo24/100

Selective Disruption of Core Regulatory Transcription [RNA-seq]

GEO Series GSE121106. Homo sapiens. 56 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2019View details →
geo24/100

PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5'-splice-site selection causing tissue-specific defects

GEO Series GSE236702. Homo sapiens. 96 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2024View details →
geo24/100

Mapping the glial transcriptome in Huntington’s disease using snRNAseq: Selective disruption of glial signatures across brain regions

GEO Series GSE281069. Homo sapiens. 44 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia [RNA-seq]

GEO Series GSE178306. Homo sapiens. 108 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2022View details →
geo24/100

Selective Disruption of Core Regulatory Transcription [ChIP-seq]

GEO Series GSE116344. Homo sapiens. 48 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2019View details →
geo24/100

Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients

GEO Series GSE130871. Pan troglodytes; Callithrix jacchus; Macaca mulatta; Homo sapiens. 49 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenDec 2019View details →
geo24/100

LATS kinase-mediated selective disruption of CTCF genomic binding

GEO Series GSE114319. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMar 2020View details →
geo24/100

Selective Disruption of Core Regulatory Transcription

GEO Series GSE120771. Homo sapiens; Mus musculus. 109 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenMay 2019View details →
geo20/100

Selective Targeting of PARP2 Inhibits Androgen Receptor Signaling and Prostate Cancer Growth Through Disruption of FOXA1 Function

GEO Series GSE114275. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2019View details →
geo20/100

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

GEO Series GSE44931. Homo sapiens. 31 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMar 2013View details →
geo20/100

Sam68-mediated disruption of CBP/β-catenin neoplastic transcriptional programming allows selective targeting of human cancer stem cells

GEO Series GSE34965. Homo sapiens. 4 samples. Type: Expression profiling by array.

openGEO-OpenOct 2017View details →
geo20/100

Selective miRNA disruption in Tregs leads to uncontrolled autoimmunity

GEO Series GSE11818. Mus musculus. 6 samples. Type: Expression profiling by array.

openGEO-OpenJun 2008View details →
geo20/100

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers [ChIP-seq]

GEO Series GSE42355. Homo sapiens. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2013View details →
geo20/100

Selective Disruption of Core Regulatory Transcription [AQuA-HiChIP]

GEO Series GSE120770. Mus musculus; Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenSep 2019View details →
geo20/100

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers [Affymetrix]

GEO Series GSE44929. Homo sapiens. 18 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMar 2013View details →
geo20/100

mTORC1/2 inhibition re-sensitizes platinum-resistant ovarian cancer by disrupting selective translation of DNA damage and survival mRNAs

GEO Series GSE116387. Homo sapiens. 24 samples. Type: Expression profiling by array; Other.

openGEO-OpenJul 2018View details →
geo20/100

Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae

GEO Series GSE87060. Saccharomyces cerevisiae. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2017View details →
geo16/100

Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia [ATAC-Seq]

GEO Series GSE212744. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2022View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record