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1,248 results for “epithelium”
Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE)
ClinicalTrials.gov study NCT01272076. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Induction With Misoprostol: Oral Mucosa Versus Vaginal Epithelium (IMPROVE)
ClinicalTrials.gov study NCT02408315. IPD Sharing: YES. Countries: 1. Publications: 3.
Cantharidin and Occlusion in Verruca Epithelium
ClinicalTrials.gov study NCT03487549. IPD Sharing: NO. Countries: 1. Publications: 1.
Topical Autologous Serum Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries
ClinicalTrials.gov study NCT01075347. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium
ClinicalTrials.gov study NCT02534233. IPD Sharing: NO. Countries: 1. Publications: 2.
Treatment of Tumors of the Choroid Plexus Epithelium
ClinicalTrials.gov study NCT00500890. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data for: Invasive investigation: Uptake and transport of L-leucine in the gill epithelium of crustaceans
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Data from: Phagocytosed photoreceptor outer segment particles within the retinal pigment epithelium show diurnal rhythmicity and variation between cone subtypes in larval zebrafish
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Atropine-functionalised gold nanoparticles binding to muscarinic receptors after passage across the intestinal epithelium
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Commensal bacteria maintain a Qa-1b-restricted unconventional CD8+ T population in gut epithelium
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Cystic fibrosis alters the structure of the olfactory epithelium and the expression of olfactory receptors affecting odor perception
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Data from: Oxidative stress in the retina and retinal pigment epithelium (RPE): role of aging, and DJ-1
<p>High levels of oxidative radicals generated by daily light exposure and high metabolic rate suggest that the antioxidant machinery of the retina and retinal pigment epithelium (RPE) is crucial for their survival. DJ-1 is a redox-sensitive protein that has been shown to have neuroprotective function in the brain in Parkinson's disease and other neurodegenerative diseases. Here, we analyzed the role of DJ-1 in the retina during oxidative stress and aging. We induced low-level oxidative stress in young (3-month-old) and old (15-month-old) C57BL/6J (WT) and DJ-1 knockout (KO) mice and evaluated effects in the RPE and retina. Absence of DJ-1 resulted in increased retinal dysfunction in response to low levels of oxidative stress. Our findings suggest that loss of DJ-1 affects the RPE antioxidant machinery, rendering it unable to combat and neutralize low-level oxidative stress, irrespective of age. Moreover, they draw a parallel to the retinal degeneration observed in AMD, where the occurrence of genetic variants may leave the retina and RPE unable to fight sustained, low-levels of oxidative stress.</p>
Data from: The presence of bacterial microcolonies on the maxillary sinus ciliary epithelium in healthy young individuals
Objective: The aim of this cross-sectional in vitro study was to evaluate the mucosal surfaces of healthy maxillary sinuses, explore different forms of bacterial microorganism colonies present on the mucous membrane, and determine a mucosal surface area they occupy. Methods: Samples of the maxillary sinus mucosa were collected from 30 healthy patients (M=11; F=19). The material was obtained during the Le Fort I osteotomy performed during corrective jaw surgery. The morphological and morphometric analysis of sinus mucosa and bacterial film that was grown on it was performed using scanning electron microscopy (SEM) as well as imaging software. Results: Scanning electron microscopy analysis showed the presence of different bacterium and bacteria-like structures in all the analyzed samples. In most cases, the bacterial film was mostly composed of diplococci-like and streptococci-like structures on the mucosa of the paranasal sinus. In any case, the mucous layer did not cover the whole lining of the evaluated sample. Each colony consists of more than 20 single bacterial cells, which has grown in aggregates. Conclusions: Under the conditions of normal homeostasis of the body, the maxillary sinuses present diverse bacterial colonization. The bacteria are dispersed or concentrated in single microcolonies of the biofilm on the border of the mucous covering the ciliary epithelium. There is no uniform layer of the biofilm covering the mucosa of the maxillary sinuses. Because the biofilm is detected on healthy individuals sinus mucosa, the clinical question if it may become pathogenic is unclear and require an explanation.
Fig. 4 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 4. Histological sections of the hindgut of a pseudergate of Serritermes serrifer. (A) Longitudinal section of the proctodeal segments, highlighting the short and cylindrical enteric valve (ev) and paunch (p). (B) Cross section of the pseudergate paunch, showing the thin epithelium (ep) and the large protozoa (pr) in the lumen (pl). (C) Longitudinal section of the abdomen of a soldier of indicating the location of the paunch followed by the rectum (r). (D) Detail of the soldier paunch with three large protozoa (pr) in the lumen and the thin epithelium involved by musculature (mu) Arrows indicate muscular fibers coating the rectum.
Fig. 2 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 2. External view of the Malpighian tubules (Mt) under scanning microscope (A) Malpighian tubules individually attached at the mesenter- o–proctodeal transition of a pseudergate of Serritermes serrifer. Arrowheads indicate the site of attachment. (B) Detail of a Malpighian tubule. m, midgut; P1, first proctodeal segment.
Fig. 7 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 7. Apical region of the paunch epithelium (ep) of a pseudergate of Serritermes serrifer. (A) Note the richness of mitochondria with conspicuous cristae (mi) associated with apical invaginations (ai). (B) Detail of the adhesion sites, in which bacteria (b) are surrounded by electron–dense material (arrowheads). Note the septate junctions (sj) between neighboring cells; c, cuticle.
Fig. 3 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 3. Histological sections of the gut of a pseudergate of Serritermes serrifer. (A) Foregut and anterior midgut. (B) and (C) Detail of the foregut and its structures. The crop (c) is oval and not separated from the gizzard (g), whereas the stomodeal valve (sv) is very short and does not penetrate deeply into the midgut (m). d, duct of the salivary glands; e, esophagus; ph, pharynx.
Fig. 5 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 5. Ultrastructure of paunch wall of a pseudergate of Serritermes serrifer. (A) and (B) The epithelium (ep) is relatively thicker in the region of the nucleus (n). Note the basal invaginations (bi) and the different bacteria morphotype (b), some of them adhered to the apical cuticle. Externally, circular (cm) and longitudinal (lm) muscular sheets involve the paunch epithelium.
Fig. 1 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 1. Digestive system in a pseudergate of Serritermes serrifer. (A) Diagram of the uncoiled gut and salivary glands (sg). (B) Scanning electron micrograph of the attachment site of the Malpighian tubules (Mt). Note the disposition of some Malpighian tubules, associated with the rectum (r). (C) Histological section of the paunch showing the lumen (pl) filled with protozoa (pr) and food debris. (D) Transmission electron micrograph of the paunch epithelium (ep). b, bacteria; c, crop; co, colon; e, esophagus; g, gizzard; i, basal invaginations; l, lumen; m, midgut; mu, musculature; n, nucleus; p, paunch; ph, pharynx; P1, first proctodeal segment.
Fig. 6 in Gut anatomy and ultrastructural features of the paunch epithelium in the Neotropical termite Serritermes serrifer (Blattaria, Isoptera, Serritermitidae)
Fig. 6. Ultrastructural features of the paunch of a pseudergate of Serritermes serrifer. (A) Detail of an epithelial cell highlighting the nucleus (n) and the deep basal invaginations (bi). Several round–shaped bacteria (b) are adhered to the apical cuticle (c), next to the apical invagination (ai) and associate mitochondria (mi). (B) An overview of the musculature sheets, which surround the epithelial cell and is composed of internal circular (cm) and external longitudinal fibers (lm). Note the myofibril (mf) of the longitudinal sheets associated with mitochondria (mi). ep, epithelium; sj, septate junction.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.