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66 results for “fluorine”
Dataset for the paper: Development and characterization of high-frequency sources for supersonic beams of fluorine radicals
<p>Raw data and analysis scripts (Matlab) for the figures of the paper: Development and characterization of high-frequency sources for supersonic beams of fluorine radicals.</p>
Negligible fractionation between fluorine and chlorine during magma ocean crystallization and implications for the origin of Earth's volatiles
<p>Research data underlying all figures in the main text and supplementary material . </p>
Role of PET/CT With Fluorine-18 Tracers of Bone Metastases in Prostate Cancer
ClinicalTrials.gov study NCT01501630. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Xenon-129 and Inert Fluorinated Gas Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary Disease
ClinicalTrials.gov study NCT02740868. IPD Sharing: NO. Countries: 1. Publications: 2.
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
ClinicalTrials.gov study NCT07232888. IPD Sharing: NO. Countries: 1. Publications: 0.
Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders
ClinicalTrials.gov study NCT02748798. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Diagnostic Usefulness of Fluorine-18-α-Methyltyrosine PET in Combination With 18F-FDG in Sarcoidosis Patient
ClinicalTrials.gov study NCT00369980. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of Novel PET Tracer Gallium [68Ga]/ Fluorine [18F] -FAPI-04 in the Diagnosis of Cardiovascular Diseases
ClinicalTrials.gov study NCT05867589. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Raw Data for Article "Oxidative Fluorination of Cyclopropylamides via Organic Photoredox Catalysis"
<p>NMR, MS and IR raw data for article "Oxidative Fluorination of Cyclopropylamides via Organic Photoredox Catalysis" published in 2020 in Angewandte Chemie: DOI: 10.1002/anie.202007864 and 10.1002/ange.202007864</p> <p>The number of the folders correspond to compounds numbers in the article. All details concerning conditions and equipment for measurements can be found in the supporting information of the article.</p>
Supporting data to Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants
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Experimental data_Fluorination of antimonene hexagons
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Electron-transfer-enabled concerted nucleophilic fluorination of azaarenes: selective C–H fluorination of quinolines
<p>NMR FID data</p>
Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for imaging of CXCR3 receptor in mouse models of atherosclerosis
<p>Background CXCR3 is a chemokine receptor and is expressed in innate and adaptive immune cells. It promotes<br> the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate<br> chemokines. Upregulation of CXCR3 and its chemokines has been found during atherosclerotic lesion formation.<br> Therefore, detection of CXCR3 by positron emission tomography (PET) radiotracer can be a useful tool for detecting the development of atherosclerosis in a noninvasive manner. Herein, we report the synthesis, radiosynthesis, and characterization of a novel fluorine-18 (F-18, <sup>18</sup>F) labeled small-molecule radiotracer for the imaging of the CXCR3 receptor in mouse models of atherosclerosis.<br> Results The reference standard <strong>1</strong> and its precursor <strong>9</strong> were synthesized over 5 steps from starting materials in good to moderate yields. The measured K<sub>i</sub> values of CXCR3A and CXCR3B were 0.81 ± 0.02 nM and 0.31 ± 0.02 nM, respectively. [<sup>18</sup>F]<strong>1</strong> was prepared by a two-step radiosynthesis with a decay-corrected radiochemical yield of 13 ± 2%, radiochemical purity > 99%, and specific activity of 44.4 ± 3.7 GBq/μmol at the end of synthesis (n = 6). The baseline studies showed that [<sup>18</sup>F]<strong>1</strong> displayed high uptake in the atherosclerotic aorta and brown adipose tissue in Apolipoprotein E (ApoE) knockout (KO) mice fed with a high-fat diet over 12 weeks. The uptake of [<sup>18</sup>F]<strong>1</strong> in these regions was reduced significantly in self-blocking studies, demonstrating CXCR3 binding specificity. Contrary to this, no significant differences in uptake of [<sup>18</sup>F]<strong>1</strong> in the abdominal aorta of C57BL/6 control mice fed with a normal diet were observed in both baseline and blocking studies, indicating increased CXCR3 expression in atherosclerotic lesions. Immunohistochemistry studies demonstrated that [<sup>18</sup>F]<strong>1</strong>-positive regions were correlated with CXCR3 expression, but some<br> atherosclerotic plaques with significant size were not detected by [<sup>18</sup>F]<strong>1</strong>, and their CXCR3 expressions were minimal.<br> Conclusion [<sup>18</sup>F]<strong>1</strong> was synthesized with good radiochemical yield and high radiochemical purity. In PET imaging<br> studies, [<sup>18</sup>F]<strong>1</strong> displayed CXCR3-specific uptake in the atherosclerotic aorta in ApoE KO mice. [<sup>18</sup>F]<strong>1</strong> visualized CXCR3<br> expression in different regions in mice aligned with the tissue histology studies. Taken together, [<sup>18</sup>F]<strong>1</strong> is a potential<br> PET radiotracer for imaging CXCR3 in atherosclerosis.</p>
Fluorine F 18 EF5 PET/CT Imaging in Patients With Locally Advanced or Recurrent/Metastatic Cervical Cancer
ClinicalTrials.gov study NCT00978874. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Fluorine F 18 Sodium Fluoride PET/CT and Whole Body and Axial MRI in Finding Metastases in Patients With Recurrent Prostate Cancer
ClinicalTrials.gov study NCT01967862. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography to Detect Hypoxia in Locally Advanced (T3-T4 and./or N1)Primary Rectal Cancer Patients
ClinicalTrials.gov study NCT00574353. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Fluorine F 18 Sodium Fluoride Positron Emission Tomography in Evaluating Response to Dasatinib in Patients With Prostate Cancer and Bone Metastases
ClinicalTrials.gov study NCT00936975. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography To Detect Hypoxia in Head and Neck Cancer Patients
ClinicalTrials.gov study NCT00606294. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Solution properties and aggregating structures for a fluorine-containing polymeric surfactant with a poly(ethylene oxide) macro-monomer
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Hexafluorophosphate-Triggered Hydrogen Isotope Exchange (HIE) in Fluorinated Environments: A Platform for the Deuteration of Aromatic Compounds via Strong Bond Activation
<p>The data set contains DFT with the program package ORCA to calculate the free enthalpy of the reaction for the hydrolysis of PF6-activated with hexafluoroisopropanol (HFIP) and reaction barriers with the help of nudged elastic band (NEB) calculation. The data in Simulated_IR contains DFT optimization and frequency calculations performed using Gaussian16 package.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.