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206
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ShareScore release 0.9.0
Dataset results
206 results for “ganglion cell”
Data from: Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are involved in circadian and other non-image forming visual responses. An open question is whether the activity of these neurons may also be under the regulation mediated by the neurohormone melatonin. In the present work, by double-staining immunohistochemical technique, we studied the expression of MT1 and MT2, two known subtypes of mammalian melatonin receptors, in rat ipRGCs. A single subset of retinal ganglion cells labeled by the specific antibody against melanopsin exhibited the morphology typical of M1-type ipRGCs. Immunoreactivity for both MT1 and MT2 receptors was clearly seen in the cytoplasm of all labeled ipRGCs, indicating that these two receptors were co-expressed in each of these neurons. Furthermore, labeling for both the receptors were found in neonatal M1 cells as early as the day of birth. It is therefore highly plausible that retinal melatonin may directly modulate the activity of ipRGCs, thus regulating non-image forming visual functions.
Data from: The functional diversity of retinal ganglion cells in the mouse
In the vertebrate visual system, all output of the retina is carried by retinal ganglion cells. Each type encodes distinct visual features in parallel for transmission to the brain. How many such 'output channels' exist and what each encodes are areas of intense debate. In the mouse, anatomical estimates range from 15 to 20 channels, and only a handful are functionally understood. By combining two-photon calcium imaging to obtain dense retinal recordings and unsupervised clustering of the resulting sample of more than 11,000 cells, here we show that the mouse retina harbours substantially more than 30 functional output channels. These include all known and several new ganglion cell types, as verified by genetic and anatomical criteria. Therefore, information channels from the mouse eye to the mouse brain are considerably more diverse than shown thus far by anatomical studies, suggesting an encoding strategy resembling that used in state-of-the-art artificial vision systems.
Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic Neuritis
ClinicalTrials.gov study NCT02939937. IPD Sharing: YES. Countries: 1. Publications: 0.
Measurment of Optic Disc Parameters, RNFL Thickness and Ganglion Cell Complex in Myopic, Hypermetropic and Emmetropic Patients Using OCT and Axial Length Measurments
ClinicalTrials.gov study NCT07241806. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Stop Retinal Ganglion Cell Dysfunction Study
ClinicalTrials.gov study NCT02390284. IPD Sharing: NO. Countries: 1. Publications: 0.
The functional organization of excitation and inhibition in the dendritic arbors of retinal direction-selective ganglion cells
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Data from: Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells
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Data from: The functional diversity of retinal ganglion cells in the mouse
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Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension
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Gene expression profile at single cell level of trigeminal ganglion non-neuronal cells
GEO Series GSE240432. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA sequencing reveals distinct transcriptional features of the purinergic signaling in mouse trigeminal ganglion
GEO Series GSE213105. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Developmental control of rod photoreceptor number via a light-dependent retrograde pathway from intrinsically photosensitive retinal ganglion cells
GEO Series GSE269102. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Genome wide chromatin accessibility analysis reveals a role for CREB in retinal ganglion cells axon growth decline in development and regeneration after optic nerve injury
GEO Series GSE163564. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Modeling retinal ganglion cell axonal pathology associated with glaucoma using human pluripotent stem cell-based microfluidic platforms
GEO Series GSE286236. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Laser capture microdissection of the ganglion cell layer for analyzing transcriptional responses induced by demyelination
GEO Series GSE245362. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNAseq data from mouse ON direction-selective ganglion cells
GEO Series GSE211344. Mus musculus. 719 samples. Type: Expression profiling by high throughput sequencing.
Single cell transcriptomics reveals lineage trajectory of the retinal ganglion cells in wild-type and Atoh7-null retinas
GEO Series GSE149040. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Retinal Ganglion Cell Expression of Cytokine Enhances Occupancy of NG2 Cell-Derived Astrocytes at the Nerve Injury Site: Implication for Axon Regeneration
GEO Series GSE196824. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Urine-derived mesenchymal stem cells-derived exosomes enhances survival and proliferation of aging retinal ganglion cells
GEO Series GSE224109. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Single-cell profiles of retinal neurons differing in resilience to injury reveal neuroprotective genes - Atlas of adult mouse retinal ganglion cells
GEO Series GSE133382. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.