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149 results for “glycan”
Fig. 2 in TIM barrel fold and glycan moieties in the structure of ICChI, a protein with chitinase and lysozyme activity
Fig. 2. The three dimensional crystal structure of ICChI where outer ball and stick (green-red) are glycan ligands, Alpha helices (red coil); parallel beta sheets (yellow arrow); random coils or loop (green); (A) topview of ICChI structure, (B) side view of ICChI structure.
Fig. 1 in TIM barrel fold and glycan moieties in the structure of ICChI, a protein with chitinase and lysozyme activity
Fig. 1. (A) Silver stained 12.5% SDS-PAGE gel of purified ICChI. Lane 1 contains molecular weight markers (Pageruler prestained protein ladder, Fermentas SM0671) and lane 2 represents pure and homogeneous ICChI protein shown by arrow. (B) Crystals of ICChI grown in 4–5 days in a hanging drop at 291 K equilibrated against 750 μl reservoir solution containing 0.005 M Cobalt chloride, 0.005 M Cadmium chloride, 0.005 M Magnesium chloride, 0.005 M Nickel chloride and 11% (w/v) PEG 3350 in 0.1 M HEPES buffer, pH 7.0. The tetragonal bipyramide-shaped crystals had a typical size of 300 × 200 × 200 μm. (C) X-ray diffraction from the crystal of ICChI protein produced interference pattern.
Fig. 5. The electron density and N in TIM barrel fold and glycan moieties in the structure of ICChI, a protein with chitinase and lysozyme activity
Fig. 5. The electron density and N-linked glycosylation sites. (A) Asparagine residue 45. (B) Asparagine residue 172. (C) Asparagine residue 194.
Fig. 4 in TIM barrel fold and glycan moieties in the structure of ICChI, a protein with chitinase and lysozyme activity
Fig. 4. The catalytic residues of the ICChI structure are: aspartate 125; glutamate 127 and tyrosine 184. The grey mesh is electron density whereas the amino acid residues are green.
GlycoSHIELD Glycan Conformer Library
<p>Dataset containing GROMACS trajectories and reference structures of glycans used by the GlycoSHIELD pipeline.</p>
Glycans Bound to Serum Haptoglobin: a Novel Gastric Cancer Tumor Biomarker
ClinicalTrials.gov study NCT02848066. IPD Sharing: NO. Countries: 1. Publications: 7.
Single-cell glycomics analysis by CyTOF-Lec reveals glycan features defining cells differentially susceptible to HIV
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Targeting the glycan of receptor binding domain with jacalin as a novel approach to developing treatment against COVID-19
<p><i><span>In silico</span></i><span> analysis revealed that a lectin, jacalin from jackfurit seeds recognize glycosylated region of receptor binding domain (RBD) of COVID-19. Jacalin binding induce conformational changes in RBD and significantly affect its interaction with human angiotensin-converting enzyme 2. The result may open up exploration of lectins based strategies against COVID-19.</span><i><span>In silico</span></i><span> analysis revealed that a lectin, jacalin from jackfurit seeds recognize glycosylated region of receptor binding domain (RBD) of COVID-19. Jacalin binding induce conformational changes in RBD and significantly affect its interaction with human angiotensin-converting enzyme 2. The result may open up exploration of lectins based strategies against COVID-19.</span></p>
Glycan Substructure Reference
<p>Table of representative glycosylation features. Glycosylation features are described using IUPAC-extended format (doi.org/10.1351/pac199668101919)</p>
Dataset associated to: Controlling the Carbon-Bio Interface via Glycan Functional Adlayers for Applications in Microbial Fuel Cell Bioanodes
<p>This file contains the dataset associated to the published research article "Controlling the Carbon-Bio Interface via Glycan Functional Adlayers for Applications in Microbial Fuel Cell Bioanodes". The dataset contains Atomic Force Microscopy, electrochemistry, Microbial Fuel Cells power output, water contact angle and quartz crystal microbalance raw data from their relative instruments. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 799175 (HiBriCarbon). This publication has also emanated from research conducted with the financial support of Science Foundation Ireland under Grant No. 13/CDA/2213 and 19/FFP/6761. The authors thank the France-Ireland PHC ULYSSES programme for support, project 36028UB. F.B. thanks Rennes Métropole for the co-funding of a Quartz Crystal Microbalance. T.P. thanks Région Bretagne for the co-funding of his PhD.</p>
Phosphatidylinositol Glycan Anchor Biosynthesis Class U Protein in Breast Cancer
ClinicalTrials.gov study NCT07130162. IPD Sharing: Not stated. Countries: 0. Publications: 5.
Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)
ClinicalTrials.gov study NCT05259696. IPD Sharing: NO. Countries: 1. Publications: 0.
Targeting the glycan of receptor binding domain with jacalin as a novel approach to developing treatment against COVID-19
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Development of a glycan microarray based method for ABO blood typing
GEO Series GSE68403. Trypanosoma cruzi; Bos taurus; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Gallus gallus; Ovis aries; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens. 220 samples. Type: Other.
Transcriptomic profiles of Streptococcus mutans UA159 grown in the presence or absence of mucins or mucin glycans
GEO Series GSE163258. Streptococcus mutans. 8 samples. Type: Expression profiling by high throughput sequencing.
IgM from common variable immunodeficiency patients narrowly recognizes erythrocyte and platelet glycans
GEO Series GSE233753. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Generalized low levels of serum N-glycans associates with young biological age and good physical condition
GEO Series GSE219147. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Detection of Chemotherapy-Resistant Pancreatic Cancer Using a Glycan Biomarker
GEO Series GSE146722. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Ascending colon-derived mucin-type O-glycans form key mucus layers encapsulating microbiota in the colon (16S rNA-seq)
GEO Series GSE133256. mouse gut metagenome. 30 samples. Type: Other.
Transcriptomic profiles of Pseudomonas aeruginosa PAO1 grown in the presence or absence of mucins or mucin-glycans
GEO Series GSE136097. Pseudomonas aeruginosa. 15 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.