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169 results for “haploid”
Data from: O father where art thou? Paternity analyses in a natural population of the haploid-diploid seaweed Chrondrus crispus
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Data from: Evolution and maintenance of haploid-diploid life cycles in natural populations: the case of the marine brown alga Ectocarpus
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Data from: The effects of haploid selection on Y chromosome evolution in two closely related dioecious plants
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Data from: Haploid selection within a single ejaculate increases offspring fitness
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Data from: Morphological, cellular and molecular evidences of chromosome random elimination in vivo upon haploid induction in maize
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Haploid, diploid, and pooled exome capture recapitulate features of biology and paralogy in two non-model tree species
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Data from: The effects of quantitative fecundity in the haploid stage on reproductive success and diploid fitness in the aquatic peat moss Sphagnum macrophyllum
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Code and processed data accompanying "Widespread haploid-biased gene expression enables sperm-level natural selection"
<p>Code and processed data required to reproduce the analysis in "Widespread haploid-biased gene expression enables sperm-level natural selection".</p>
The plot thickens: Haploid and triploid-like thalli, hybridization, and biased mating type ratios in Letharia
<p>The study of the reproductive biology of lichen fungal symbionts has been traditionally challenging due to their complex and symbiotic lifestyles. Against the common belief of haploidy, a recent genomic study found a triploid-like signal in <em>Letharia</em>. Here, we used genomic data from a pure culture and from thalli, together with a PCR survey of the MAT locus, to infer the genome organization and reproduction in <em>Letharia</em>. We found that the read count variation in the four <em>Letharia</em> specimens, including the pure culture derived from a single sexual spore of <em>L. lupina</em>, is consistent with haploidy. By contrast, the <em>L. lupina </em>read counts from a thallus' metagenome are triploid-like. Characterization of the mating-type locus revealed a conserved heterothallic configuration across the genus, along with auxiliary genes that we identified. We found that the mating-type distributions are balanced in North America for <em>L. vulpina</em> and <em>L. lupina</em>, suggesting widespread sexual reproduction, but highly skewed in Europe for <em>L. vulpina</em>, consistent with predominant asexuality. Taken together, we propose that <em>Letharia</em> fungi are heterothallic and typically haploid, and provide evidence that triploid-like individuals are rare hybrids between <em>L. lupina</em> and an unknown <em>Letharia</em> lineage, reconciling classic systematic and genetic studies with recent genomic observations.</p>
Data from: Haploids adapt faster than diploids across a range of environments
Despite a great deal of theoretical attention, we have limited empirical data about how ploidy influences the rate of adaptation. We evolved isogenic haploid and diploid populations of Saccharomyces cerevisiae for 200 generations in seven different environments. We measured the competitive fitness of all ancestral and evolved lines against a common competitor and find that in all seven environments haploid lines adapted faster than diploids, significantly so in three environments. We apply theory that relates the rates of adaptation and measured effective population sizes to the properties of beneficial mutations. We obtained rough estimates of the average selection coefficients in haploids between 2-10% for these first selected mutations. Results were consistent with semi-dominant to dominant mutations in four environments and recessive to additive mutations in two other environments. These results are consistent with theory that predicts haploids should evolve faster than diploids at large population sizes.
The predicted haploid gene set of the genome of Nitzschia putrida
<p>Secondary loss of photosynthesis is observed across almost all plastid-bearing branches of the eukaryotic tree of life. However, genome-based insights into the transition from a phototroph into a secondary heterotroph have so far only been revealed for parasitic species. Free-living organisms can yield unique insights into the evolutionary consequence of the loss of photosynthesis, as the parasitic lifestyle requires specific adaptations to host environments. Here we report on the diploid genome of the free-living diatom <i>Nitzschia putrida </i>(35 Mbp), a non-photosynthetic osmotroph whose photosynthetic relatives contribute ca. 40% of net oceanic primary production. Comparative analyses with photosynthetic diatoms and heterotrophic algae with parasitic lifestyle revealed that a combination of gene loss, the accumulation of genes involved in organic carbon degradation, a unique secretome and the rapid divergence of conserved gene families involved in cell wall and extracellular metabolism appear to have facilitated the lifestyle of a free-living secondary heterotroph.</p>
Diploid and haploid assemblies and annotation of monoecious shrub willow (Salix purpurea), clone ID 94003
<p>The Salicaceae are dioecious perennials that utilize different sex determination systems. There is substantial interest in understanding the impacts of hybridization, speciation, and polyploidy on sex chromosome evolution. Here, a rare monoecious <em>S. purpurea</em> genotype, 94003, was assembled. Based on sequence alignments to dioecious and monoecious genomes, a 1.15 Mb sex-linked region on Chr15W was identified as absent in monecious plants. Inheritance of this structural variation is responsible for the loss of a male-suppressing function in what would otherwise be genetic females, resulting in monoecy or lethality, if homozygous.</p>
Haploid Allogeneic Transplant Using the CliniMACS System
ClinicalTrials.gov study NCT00185679. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Diploid and haploid assemblies and annotation of monoecious shrub willow (Salix purpurea), clone ID 94003
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The plot thickens: Haploid and triploid-like thalli, hybridization, and biased mating type ratios in Letharia
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Data from: Evolution of haploid–diploid life cycles when haploid and diploid fitnesses are not equal
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Data from: Evolution of haploid selection in predominantly diploid organisms
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Data from: Haploids adapt faster than diploids across a range of environments
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The predicted haploid gene set of the genome of Nitzschia putrida
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Data from: Fixation probability in a haploid-diploid population
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.