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33
datasets available to search
ShareScore release 0.9.0
Dataset results
33 results for “linking elements”
Mapping cis-regulatory elements in human excitatory and inhibitory neurons links psychiatric disease heritability and activity-regulated transcriptional programs [RNA-seq]
GEO Series GSE196855. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin [EPIC methylation data on cell lines and PDXs]
GEO Series GSE134217. Homo sapiens. 43 samples. Type: Methylation profiling by array; Third-party reanalysis.
Mapping cis-regulatory elements in human excitatory and inhibitory neurons links psychiatric disease heritability and activity-regulated transcriptional programs [ATAC-seq]
GEO Series GSE196854. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. [Expression profile of human PDAC primary cells]
GEO Series GSE134092. Homo sapiens. 7 samples. Type: Expression profiling by array.
Experimental manipulation of selfish genetic elements links genes to microbial community function
<p>Microbial communities underpin earth’s biological and biogeochemical processes, but their complexity hampers understanding. Here we draw upon predictions from the theory of selfish genetic elements (SGEs), combined with approaches from experimental evolution, comparative metagenomics and biochemistry, and show how naturally occurring SGEs can be used to manipulate genes that underpin community function. Communities comprising hundreds of bacterial genera established from garden compost were propagated with bi-weekly transfer for one year in nitrogen-limited minimal medium with cellulose (paper) as sole carbon source. At each transfer, SGEs from one set of independent communities were collected, pooled and redistributed among this same set of communities (horizontal treatment). A control was included in which SGEs never moved beyond the community in which they were originally present (vertical treatment). SGEs along with genes of ecological relevance were rapidly amplified across horizontal communities and their dynamics tracked. Enrichment of genes implicated in nitrogen metabolism, and particularly ammonification, led to biochemical assays that showed a significant functional difference between communities subject to horizontal versus vertical treatments. This simple experimental strategy offers a powerful new approach for unravelling dynamical processes underpinning microbial community function.</p>
Examining the Link Between Trace Elements and Cardiovascular Disease Risk Factors in Young Adults
ClinicalTrials.gov study NCT00318734. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The promoter interactome of cardiomyocytes differentiated from human embryonic stem cells links regulatory elements to cardiac gene promoters
GEO Series GSE100720. Homo sapiens. 3 samples. Type: Other.
Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression
GEO Series GSE252653. Homo sapiens; Mus musculus. 67 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mapping cis-regulatory elements in human excitatory and inhibitory neurons links psychiatric disease heritability and activity-regulated transcriptional programs
GEO Series GSE196207. Homo sapiens. 49 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mapping cis-regulatory elements in human excitatory and inhibitory neurons links psychiatric disease heritability and activity-regulated transcriptional programs
GEO Series GSE196856. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
CTCF and Cohesin link sex-biased distal regulatory elements to sex-biased gene expression in mouse liver
GEO Series GSE131128. Mus musculus. 43 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Small molecule inhibitors of HIF-2a translation link its 5’-UTR Iron-Responsive Element (IRE) to oxygen sensing
GEO Series GSE13818. Homo sapiens. 26 samples. Type: Expression profiling by array.
Widespread chromatin accessibility at repetitive elements links embryonic stem cells with human cancer
GEO Series GSE75172. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.