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Dataset results
150 results for “metabolic networks”
Fig. 4 in Establishing the metabolic network of isoquinoline alkaloids from the Macleaya genus
Fig. 4. Proposed new biosynthesis pathways for protoberberine (97), sanguinarine (144) and chelerythrine (145).
Fig. 2 in Establishing the metabolic network of isoquinoline alkaloids from the Macleaya genus
Fig. 2. Proposed metabolic network of isoquinoline alkaloids in the Macleaya genus. a the solid arrow represents verified biosynthesis pathways; b the dotted arrow represents unverified pathways, c the double arrow represents two or more steps needed for biosynthesis; d MT, GOA, and COA are abbreviation for methyl transferase, glycosyltransferase, and cyclooxygenase, respectively; e the red moieties represent the changed substituent groups, and f the blue moieties represent the 13C -labeled benzene ring. (For 6 interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
nSeP: Detecting Neonatal Sepsis by Immune-Metabolic Network Analysis
ClinicalTrials.gov study NCT03777670. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Establishment of Multiple Point Prediction Model About Tacrolimus Metabolic Differences Based on Genetic Network After Liver Transplantation and the Application of Multicenter
ClinicalTrials.gov study NCT02752529. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Spatiotemporal Dynamics and Prognostic Value of the 18F-FDG PET Neuro-Metabolic Network
ClinicalTrials.gov study NCT07203495. IPD Sharing: YES. Countries: 1. Publications: 4.
Large-scale metabolic interaction network of the mouse and human gut microbiota
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Data from: Widespread dysregulation of long non-coding genes associated with fatty acid metabolism, cell division, and immune response gene networks in xenobiotic-exposed rat liver
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Dataset for: Contingent evolution of alternative metabolic network topologies determines whether cross-feeding evolves
<p>Data generated with VirtualMicrobes (<a href="https://bitbucket.org/thocu/virtual-microbes">https://bitbucket.org/thocu/virtual-microbes</a>) supporting: </p> <p>J.Meijer, B. van Dijk, P. Hogeweg. Contingent evolution of alternative metabolic network topologies determines whether cross-feeding evolves. Nature Communication Biology (2020)</p>
Dataset of Insulin sensitizers for improving endocrine metabolism in overweight women with PCOS: a network meta-analysis
<p><span><b>Objective: </b>To evaluate the efficacy of insulin sensitizers on menstrual frequency, sex hormone and metabolic parameters in overweight women with PCOS. </span></p> <p><span><b>Methods:</b> We searched multiple databases from inception to September 2019 for RCTs. Network meta-analysis was conducted using multivariate random effects method. </span></p> <p><span><b>Results:</b> 14 trials reporting on 619 women were included. Compared with metformin, metformin + TZDs was more superior in menstrual recovery (WMD 3.68, 95% CrI 1.65 to 8.20), metformin + GLP-1 receptor agonists was more effective in decreasing AND (WMD -2.53, 95% CrI -3.96 to -1.09), both metformin + GLP-1 receptor agonists (WMD 9.22, 95% CrI 5.46 to 12.98) and metformin + TZDs (WMD 4.30, 95% CrI 0.78 to 7.82) were more effective in increasing SHBG, while TZDs was less effective in decreasing BMI (WMD 1.69, 95% CrI 0.72 to 2.66). Compared with GLP-1 receptor agonists, metformin + GLP-1 receptor agonists was associated with higher SHBG (WMD 7.80, 95% CrI 4.75 to 10.85), lower FT (WMD -1.77, 95% CrI -3.25 to -0.29), lower AND (WMD -2.70, 95% CrI -3.91 to -1.50) and lower FG (WMD -0.41, 95% CrI -0.73 to -0.08).</span></p> <p><span><b>Conclusion: </b>For overweight women with PCOS, both metformin combined with GLP-1 receptor agonists and metformin combined with TZDs appear superior to monotherapy in improving hyperandrogenemia. Metformin combined with TZDs could be particularly effective in promoting the recovery of menstruation. Metformin combined with GLP-1 receptor agonists has additional advantage in improving fasting glucose when compared with GLP-1 receptor agonists alone. TZDs is inferior to metformin in decreasing BMI.</span></p>
NMR and HRMS raw data for "Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking"
<p>Raw NMR data and HRMS data for synthesized compounds</p>
Fig. 3 in Establishing the metabolic network of isoquinoline alkaloids from the Macleaya genus
Fig. 3. TICs of 0-day (A) and 36-day-old (B) tissue culture seedlings.
Data from: Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster.
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Data from: Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis
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Data from: Insulin sensitizers for improving endocrine metabolism in overweight women with PCOS: a network meta-analysis
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Genome-wide distribution of AdpA, a global regulator for secondary metabolism and morphological differentiation in Streptomyces, revealed the extent and complexity of the AdpA regulatory network.
GEO Series GSE33994. Streptomyces griseus. 9 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
LKB1 loss links the serine metabolic network to DNA methylation and tumourigenesis
GEO Series GSE86145. Mus musculus. 13 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Azithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation
GEO Series GSE197658. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.
Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome [AML12]
GEO Series GSE193670. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The evolution of TF-regulatory network of core C4 metabolic pathway genes in the genus of Flaveria [low CO2 vs ctrl]
GEO Series GSE145640. Flaveria ramosissima; Flaveria robusta; Flaveria trinervia; Flaveria sonorensis. 24 samples. Type: Expression profiling by high throughput sequencing.
Long-term disulfiram supplementation activates an anti-inflammatory metabolic network to lower diet-induced obesity and related co-morbidities
GEO Series GSE110200. Mus musculus. 32 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.