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1,278 results for “microarray analysis”
Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)
ClinicalTrials.gov study NCT00127036. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Microarray Analysis of Space-flown Murine Thymus Tissue
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene expression of space-flown thymic tissue and identified distinct classes of up-regulated genes during this process. We report here microarray gene expression analysis in young adult C57BL/6NTac mice at 8 weeks of age after exposure to spaceflight aboard the space shuttle (STS-118) for a period of 13 days. Upon conclusion of the mission thymus lobes were extracted from space flown mice (FLT) as well as age- and sex-matched ground control mice similarly housed in animal enclosure modules (AEM). mRNA was extracted and an automated array analysis for gene expression was performed. Examination of the microarray data revealed 970 individual probes that had a 1.5 fold or greater change. When these data were averaged (n=4) we identified 12 genes that were significantly up- or down-regulated by at least 1.5 fold after spaceflight (p < 0.05). Together these data demonstrate that spaceflight induces significant changes in the thymic mRNA expression of genes that regulate stress glucocorticoid receptor metabolism and T cell signaling activity. These data explain in part the reported systemic compromise of the immune system after exposure to the microgravity of space.
Comparative gene expression analysis in the Arabidopsis thaliana root apex using RNA-seq and microarray transcriptome profiles
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse environments is important and challenging especially when the samples are limiting and precious such as in spaceflight. The feasibility of using tiny root sections for transcriptome analysis was examined in this study. To understand the gene expression profiles of the root apex Arabidopsis thaliana Col-0 roots were sectioned into Zone-I (0.5 mm root cap and meristematic zone) and Zone-II (1.5 mm transition elongation and growth terminating zone). Gene expression was analyzed using microarray and RNA seq. Both the techniques arrays and RNA-Seq identified 4180 common genes as differentially expressed (with > two-fold changes) between the zones. In addition 771 unique genes and 19 novel TARs were identified by RNA-Seq as differentially expressed which were not detected in the arrays. Single root tip zones can be used for full transcriptome analysis; further the root apex zones are functionally very distinct from each other. RNA-Seq provided novel information about the transcripts compared to the arrays. These data will help optimize transcriptome techniques for dealing with small rare samples.
Whole-genome microarray analysis of human skin fibroblasts
GEO Series GSE69447. Homo sapiens. 9 samples. Type: Expression profiling by array.
Differentially Expressed MiRNAs in Epithelial Ovarian Cancer Tissue and Serum Samples by MiRNA Microarray Analysis
GEO Series GSE216150. Homo sapiens. 32 samples. Type: Non-coding RNA profiling by array.
Microarray analysis of rice plants fumigated with ozone
GEO Series GSE11157. Oryza sativa Japonica Group; Oryza sativa. 12 samples. Type: Expression profiling by array.
Microarray analysis of genes impacted by 5 day knockdown of SLC24A5 in normal human melanocytes.
GEO Series GSE21565. Homo sapiens. 30 samples. Type: Expression profiling by array.
Microarray analysis of heart gene expression in wild type and JMJD2A heart specific transgenic mice after sham and thoracic aortic constriction surgery
GEO Series GSE27689. Mus musculus. 6 samples. Type: Expression profiling by array.
Analysis of the genome content of Lactococcus garvieae by genomic interspecies microarray hybridization
GEO Series GSE19005. Streptococcus pneumoniae; Lactococcus lactis subsp. lactis Il1403; Lactococcus garvieae; Lactococcus lactis subsp. lactis. 32 samples. Type: Genome variation profiling by array.
Microarray analysis of xenograft model to characterize the CNS leukemia
GEO Series GSE81517. Homo sapiens. 10 samples. Type: Expression profiling by array.
Microarray analysis of mouse gene expression in metronomic cyclophosphamide-treated human glioma U251 xenografts implanted in scid mice
GEO Series GSE60866. Homo sapiens; Mus musculus. 2 samples. Type: Expression profiling by array.
Systematic transcriptome analysis of white tea based on microarray
GEO Series GSE123402. Homo sapiens. 2 samples. Type: Expression profiling by array.
A Comparison of microarray and MPSS Technology Platforms for Expression Analysis of Arabidopsis
GEO Series GSE8994. Arabidopsis thaliana. 44 samples. Type: Expression profiling by array.
Screening Hub Genes Related to the Recovery Phase of Irradiation Injury by Microarray Analysis Combined with Integrated Gene Network
GEO Series GSE28195. Mus musculus. 5 samples. Type: Expression profiling by array.
Long Oligonucleotide Microarrays for African Green Monkey Gene Expression Profile Analysis
GEO Series GSE6982. Macaca mulatta; Homo sapiens; Chlorocebus sabaeus. 14 samples. Type: Expression profiling by array.
Whole genome microarray analysis of mouse liver subjected to Leishmania donovani infection
GEO Series GSE38985. Mus musculus. 5 samples. Type: Expression profiling by array.
Genome-wide microarray analysis of human fibroblasts in response to indomethacin and nimesulide.
GEO Series GSE63239. Homo sapiens. 36 samples. Type: Expression profiling by array.
Arraystar m6A-mRNA Epitranscriptomic Microarray Analysis of Atopic Dermatitis and healthy controls
GEO Series GSE222771. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by array; Expression profiling by array.
Microarray analysis of B16 cells in pigmentation oscillator
GEO Series GSE54359. Mus musculus. 12 samples. Type: Expression profiling by array.
Transcriptome analysis of Escherichia coli O157:H7 EDL933 inside Acanthamoeba using microarrays
GEO Series GSE16762. Escherichia coli; Escherichia coli O157:H7 str. EDL933. 9 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.