Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
4,498
datasets available to search
ShareScore release 0.7.1
Dataset results
4,498 results for “mitochondrial”
Molecular dynamic trajectory of calcium binding wild type for the article "Ca 2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition"
<p>ATP synthase molecular dynamics simulations files for wild type of the beta subunit binding calcium:</p> <p>50ns trajectory (ATPsynth_woh2o_Ca_wt.dcd) and corresponding psf file (ATPsynth_ca_wt.psf)</p> <p> </p>
Molecular dynamic trajectory of magnesium binding T163S mutant for the article "Ca 2+ binding to F-ATP synthase β subunit triggers the mitochondrial permeability transition"
<p>ATP synthase molecular dynamics simulations files for T163S mutants of the beta subunit binding magnesium:</p> <p>50ns trajectory (ATPsynth_woh2o_Mg_mut.dcd) and corresponding psf file (ATPsynth_mg_mut.psf)</p> <p> </p>
Fig. 2 in Phylogenetic Relationships Of Malayan And Malagasy Pygmy Shrews Of The Genus Suncus (Soricomorpha: Soricidae) Inferred From Mitochondrial Cytochrome B Gene Sequences
Fig. 2. The neighbour-joining (A) and Bayesian (B) trees for Suncus inferred from 1140 base-pairs of cytochrome b gene sequence. Bootstrap and posterior probability values are given above branches.
Fig. 1 in Phylogenetic Relationships Of Malayan And Malagasy Pygmy Shrews Of The Genus Suncus (Soricomorpha: Soricidae) Inferred From Mitochondrial Cytochrome B Gene Sequences
Fig. 1. Male Malayan pygmy shrew (Suncus malayanus) captured in the Cameron Highlands, Pahang, Peninsular Malaysia, in a pitfall trap set on the forest floor. Notice the characteristic large ears and dark fine pelage.
Fig. 2 in Preliminary Report On Mitochondrial Dna Variation In Macaca Fascicularis From Singapore
Fig. 2. Neighbor-joining trees for each of five mtDNA gene fragments including: A, cytochrome b; B, 12s rRNA; C, COI; D, COII; E, COIII. Bootstrap support values are presented at each node.
Fig. 3 in Preliminary Report On Mitochondrial Dna Variation In Macaca Fascicularis From Singapore
Fig. 3. Maximum parsimony trees for each of five mtDNA gene fragments including: A, cytochrome b; B, 12s rRNA; C, COI; D, COII; E, COIII. Bootstrap support values are presented at each node.
Fig. 1 in Preliminary Report On Mitochondrial Dna Variation In Macaca Fascicularis From Singapore
Fig. 1. Map of sample locations within the Bukit Timah (BTNR) and Central Catchment (CCNR) Nature Reserves.
Figure 3. The phylogenetic relationship between G in The Complete Mitochondrial Genome of Glischropus bucephalus (Vespertilionidae; Chiroptera) Provides New Evidence for Pipistrellus Paraphyly
Figure 3. The phylogenetic relationship between G. bucephalus and the other Pipistrellini species is inferred by maximum likelihood analysis based on cytb sequences. The numbers in the branches show the bootstrap values. Vespertilio species are used as outgroups.
Figure 1 in The Complete Mitochondrial Genome of Glischropus bucephalus (Vespertilionidae; Chiroptera) Provides New Evidence for Pipistrellus Paraphyly
Figure 1. Map of the G. bucephalus mitogenome. Gray color indicates the PCG regions; red color— tRNAs; yellow color—rRNAs. The heavy strand in the outer circle encodes 28 genes, whereas 9 genes are encoded in the light strand in the inner circle.
Figure 2. The phylogenetic relationship between G in The Complete Mitochondrial Genome of Glischropus bucephalus (Vespertilionidae; Chiroptera) Provides New Evidence for Pipistrellus Paraphyly
Figure 2. The phylogenetic relationship between G. bucephalus and the other Vespertilioninae species is inferred by the maximum likelihood analysis based on the concatenated protein-coding gene sequences. The bootstrap values (indicated by the slashes on the branches) correspond to the trees constructed on full sequences (three codon positions), the first two codon positions (third positions omitted), and two positions with the exclusion of the Nd6 gene. The asterisks mark branches that in the second or third case have a different topology than shown. Myotis species are used as outgroups.
PacBio HiFi de-novo assembled genome and mitochondrial genome for Orbicella faveolata
<p>Final assembly using Funannotate of <i>Orbicella faveolata</i> from PacBio HiFi reads. For full methods please see the publication. </p>
Fig. 3 in Broad Taxon Sampling of Ciliates Using Mitochondrial Small Subunit Ribosomal DNA
Fig. 3. Concatenated mitochondrial and nuclear SSU-rDNA tree inferred from an alignment of 2333 included characters. Most likely ML tree is shown; the BI tree was the same for well-supported nodes. Node support is as in Fig 1.
Fig. 2 in Broad Taxon Sampling of Ciliates Using Mitochondrial Small Subunit Ribosomal DNA
Fig. 2. Nuclear SSU-rDNA tree inferred from an alignment of 1543 included characters. The most likely ML tree is shown; the BI tree was the same for well-supported nodes. Node support is as in Fig 1.
Fig. 1 in Broad Taxon Sampling of Ciliates Using Mitochondrial Small Subunit Ribosomal DNA
Fig. 1. Mitochondrial SSU-rDNA tree inferred from an alignment of 790 included characters. The most likely ML tree is shown; the BI tree was the same for well-supported nodes. Node support is shown as: ML bootstraps/BI posterior probability. Values ≤ 50 are shown as "-".
Pronounced differentiation on the Z chromosome and parts of the autosomes in crowned sparrows contrasts with mitochondrial paraphyly: implications for speciation
<p>When a single species evolves into multiple descendent species, some parts of the genome can play a key role in the evolution of reproductive isolation while other parts flow between the evolving species via interbreeding. Genomic evolution during the speciation process is particularly interesting when major components of the genome—for instance, sex chromosomes vs. autosomes vs. mitochondrial DNA—show widely differing patterns of relationships between three diverging populations. The golden-crowned sparrow (<em>Zonotrichia atricapilla</em>) and the white-crowned sparrow (<em>Zonotrichia leucophrys</em>) are phenotypically differentiated sister species that are largely reproductively isolated despite possessing similar mitochondrial genomes, likely due to recent introgression. We assessed variation in more than 45,000 single nucleotide polymorphisms (SNPs) to determine the structure of nuclear genomic differentiation between these species and between two hybridizing subspecies of <em>Z. leucophrys</em>. The two <em>Z. leucophrys</em> subspecies showed moderate levels of relative differentiation and patterns consistent with a history of recurrent selection in both ancestral and daughter populations, with much of the sex chromosome Z and a large region on the autosome 1A showing increased differentiation compared to the rest of the genome. The two species <em>Z. leucophrys</em> and <em>Z. atricapilla</em> show high relative differentiation and strong heterogeneity in the level of differentiation among various chromosomal regions, with a large portion of the sex chromosome (Z) showing highly divergent haplotypes between these species. Studies of speciation often emphasize mitochondrial DNA differentiation, but speciation between <em>Z. atricapilla</em> and <em>Z. leucophrys</em> appears primarily associated with Z chromosome divergence and more moderately associated with autosomal differentiation, whereas mitochondria appear highly similar due apparently to recent introgression. These results add to the growing body of evidence for highly heterogeneous patterns of genomic differentiation during speciation, with some genomic regions showing lack of gene flow between populations many hundreds of thousands of years before other genomic regions.</p>
Image quantification data for: Activity-dependent mitochondrial ROS signaling regulates recruitment of glutamate receptors to synapses
<p>Our understanding of mitochondrial signaling in the nervous system has been limited by the technical challenge of analyzing mitochondrial function <em>in vivo</em>. In the transparent genetic model <em>Caenorhabditis elegans, </em>we were able to manipulate and measure mitochondrial ROS (reactive oxygen species) signaling of individual mitochondria as well as neuronal activity of single neurons <em>in vivo</em>. Using this approach, we provide evidence supporting a novel role for mitochondrial ROS signaling in dendrites of excitatory glutamatergic <em>C. elegans</em> interneurons. Specifically, we show that following neuronal activity, dendritic mitochondria take up calcium (Ca<sup>2+</sup>) via the mitochondrial Ca<sup>2+</sup> uniporter MCU-1 which results in an upregulation of mitochondrial ROS production. We also observed that mitochondria are positioned in close proximity to synaptic clusters of GLR-1, the <em>C. elegans</em> ortholog of the AMPA subtype of glutamate receptors that mediate neuronal excitation. We show that synaptic recruitment of GLR-1 is upregulated when MCU-1 function is pharmacologically or genetically impaired but is downregulated by mitoROS signaling. Thus, signaling from postsynaptic mitochondria may regulate excitatory synapse function to maintain neuronal homeostasis by preventing excitotoxicity and energy depletion.</p>
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis
<p>This study elucidates the essential role of pyrimidines in supporting mitochondrial pyruvate oxidation and the tricarboxylic acid (TCA) cycle. Quantitative assessment of metabolite changes in response to alterations in cellular pyrimidine levels was conducted using liquid chromatography-mass spectrometry. Concurrently, western blot analysis was employed to characterize the expression of metabolic enzymes potentially involved in this regulatory process. To enhance precision, metabolic activity measurements were conducted under both untreated and pyrimidine-depleted conditions using radioactivity-based assays, isotope tracers, and Seahorse analyzers. The comprehensive dataset includes experimental quantifications of metabolite abundance, accurate assessments of metabolic activity, and protein levels of metabolic and signaling enzymes.</p>
Fig. 2 in Phylogeography Of The Western Populations Of Stylodipus Telum (Rodentia, Dipodidae) Based On Mitochondrial Dna
Fig. 2. Phylogeographic reconstruction of S. telum based on cytb. BI posterior probability / ML bootstrap support per 1000 replications is indicated at the nodes (only values over 70 % are shown). Photo: S. telum falzfeini from Sagi (Oleshki District) by M. Rusin, 2017-05-17.
Fig. 1 in Phylogeography Of The Western Populations Of Stylodipus Telum (Rodentia, Dipodidae) Based On Mitochondrial Dna
Fig. 1. Sampling localities of S. telum used in the study. White — range of S. telum falzfeini (original unpublished data) and green — range of S. telum turovi (Shenbrot et al., 1995).
Figure 1 in Mitochondrial genomes of four pierid butterfly species (Lepidoptera: Pieridae) with assessments about Pieridae phylogeny upon multiple mitogenomic datasets
Figure 1. Circular map of Baltia butleri, Talbotia naganum, Pontia callidice, Pontia daplidice mitochondrial genome. COI, COII, and COIII refer to the cytochrome oxidase subunits; CytB refers to cytochrome B; ATP6 and ATP8 refer to subunits 6 and 8 of F0 ATPase; ND1-6 refers to the components of NADH dehydrogenase. The tRNAs locations are marked by the color blocks and labeled by the IUPAC-IUB single letter amino acid code. L1, L2, S1, and S2 denote tRNALeu (CUN), tRNALeu (UUR), tRNASer (AGN), and tRNASer (UCN), respectively. The non-underlined genes are transcribed on the majority strand whereas the underlined genes are transcribed on the minority strand.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.