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39
datasets available to search
ShareScore release 0.9.0
Dataset results
39 results for “molecular convergence”
A single-cell atlas of bobtail squid visual and nervous system highlights molecular principles of convergent evolution
GEO Series GSE203527. Euprymna berryi. 74 samples. Type: Expression profiling by high throughput sequencing.
Molecular Specificity, Convergence and Constraint Shape Adaptive Evolution in Nutrient-Poor Environments [GE]
GEO Series GSE52786. Saccharomyces cerevisiae. 22 samples. Type: Expression profiling by array.
A foundational atlas of autism protein interactions reveals molecular convergence [scRNA-seq]
GEO Series GSE285270. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Molecular pathogenesis of several neurodevelopmental disorders converges on MeCP2-TCF20 complex interactions
GEO Series GSE179229. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Molecular Specificity, Convergence and Constraint Shape Adaptive Evolution in Nutrient-Poor Environments
GEO Series GSE52787. Saccharomyces cerevisiae. 65 samples. Type: Expression profiling by array; Genome variation profiling by genome tiling array.
Molecular convergence between Down syndrome and Fragile X syndrome identified using human pluripotent stem cell models
GEO Series GSE144857. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
Mutations in distinct translation-dependent quality control pathways lead to convergent molecular pathogenesis and neurodevelopmental defects.
GEO Series GSE162556. Mus musculus. 41 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic Analysis of Autism Brain Reveals Convergent Molecular Pathology [array data]
GEO Series GSE28521. Homo sapiens. 79 samples. Type: Expression profiling by array.
A molecular shift in limb identity underlies the convergent evolution and development of feathered feet
GEO Series GSE67875. Columba livia. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Protein Interactome Reveals Converging Molecular Pathways Among Autism Disorders
GEO Series GSE29576. Homo sapiens. 288 samples. Type: Genome variation profiling by array.
Transcriptomic analysis of autistic brain reveals convergent molecular pathology [high-throughput sequence data]
GEO Series GSE30573. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Data from: Convergently evolved toxic secondary metabolites in plants drive the parallel molecular evolution of insect resistance
Natural selection imposed by natural toxins has led to striking levels of convergent evolution at the molecular level. Cardiac glycosides represent a group of plant toxins that block the Na,K-ATPase, a vital membrane protein in animals. Several herbivorous insects have convergently evolved resistant Na,K-ATPases, and in some species, convergent gene duplications have also arisen, likely to cope with pleiotropic costs of resistance. To understand the genetic basis and predictability of these adaptations, we studied five independent lineages of leaf-mining flies (Diptera: Agromyzidae). These flies have colonized host plants in four botanical families that convergently evolved cardiac glycosides of two structural types: cardenolides and bufadienolides. We compared each of six fly species feeding on such plants to a phylogenetically related but nonadapted species. Irrespective of the type of cardiac glycoside in the host plant, five out of six exposed species displayed substitutions in the cardiac glycoside–binding site of the Na,K-ATPase that were previously described in other insect orders; in only one species was the gene duplicated. In vitro assays of nervous tissue extractions confirmed that the substitutions lead to increased resistance of the Na,K-ATPase. Our results demonstrate that target site insensitivity of Na,K-ATPase is a common response to dietary cardiac glycosides leading to highly predictable amino acid changes; nonetheless, convergent evolution of gene duplication for this multifunctional enzyme appears more constrained.
Data from: Convergently evolved toxic secondary metabolites in plants drive the parallel molecular evolution of insect resistance
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Molecular Specificity, Convergence and Constraint Shape Adaptive Evolution in Nutrient-Poor Environments [aCGH]
GEO Series GSE52696. Saccharomyces cerevisiae. 43 samples. Type: Genome variation profiling by genome tiling array.
Comparing dormancy in two distantly related tunicates reveals morphological, molecular, and ecological convergences and repeated co-option
GEO Series GSE198056. Polyandrocarpa zorritensis; Clavelina lepadiformis. 36 samples. Type: Expression profiling by high throughput sequencing.
A foundational atlas of autism protein interactions reveals molecular convergence [CUT&Tag]
GEO Series GSE285273. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
FIGURE 3 in Phylogenetic relationships in the genus Astropecten Gray (Paxillosida: Astropectinidae) on a global scale: molecular evidence for morphological convergence, species-complexes and possible cryptic speciation
FIGURE 3. Total evidence molecular phylogeny of 117 specimens of Astropecten and seven outgroup taxa based on combined 12S, 16S and COI sequences of the mitochondrial DNA. (a) Maximum parsimony strict consensus tree of 2600 most parsimonious trees (length = 3447). Above nodes: bootstrap support values above 50% from 1,000 replicates. Below nodes: decay indices. (b) Bayesian inference tree resulting from 9,500 trees based on the GTR+I+Γ model. Posterior probabilities are indicated above nodes. See Table 1 for collection locality of specimens. EP = East Pacific, WA = West Atlantic; CP = Central Pacific; WP = West Pacific; IP = Indo-Pacific; IO = Indian Ocean; EA = East Atlantic, EM = East Mediterranean, WM = West Mediterranean
Convergent molecular pathways that induce immunoglobulin light-chain recombination
GEO Series GSE10273. Mus musculus. 9 samples. Type: Expression profiling by array.
A common molecular basis to the convergent evolution of the selfing syndrome in Capsella.
GEO Series GSE140465. Capsella grandiflora; Capsella orientalis; Capsella rubella. 27 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.