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75 results for “priming effects”
Evaluation of Priming Effects by PLAI Vaccine on the Subsequent Response to Inactivated H5N1 Vaccine
ClinicalTrials.gov study NCT02229357. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Cool Prime Comparative Effectiveness Study for Mild HIE
ClinicalTrials.gov study NCT04621279. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Root influence on soil nitrogen availability and microbial community dynamics results in contrasting rhizosphere priming effects in pine and spruce soil
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Deciphering linkages between microbial communities and priming effects in lake sediments with different salinity
<p>Priming effects (PEs) and their associated microbial drivers are not well studied in lake sediments. Here, we investigated PEs and underlying potential microbial drivers in the sediments of lakes on the Qinghai-Tibetan Plateau (QTP). Sediments were collected from three QTP lakes with different salinity, followed by microcosm construction and subsequent incubation at in-situ temperature. The sediment microcosms were amended with <sup>13</sup>C-labeled glucose, on which PE intensities were evaluated in the incubations on the 7<sup>th</sup> and 42<sup>nd</sup> day. Positive PEs were observed in all the studied lake sediment microcosms. PE intensities exhibited significantly (<i>P</i> < 0.05) linear correlations with most of the measured physicochemical factors (e.g., salinity, sediment total nitrogen/phosphorus and ratios of carbon: nitrogen), and such linear correlations were inverse for the early (i.e., on the 7<sup>th</sup> day) and late (i.e., on the 42<sup>nd</sup> day) PEs. Prokaryotic and fungal community compositions significantly changed owing to glucose addition in the studied lake microcosms, suggesting that both prokaryotes and fungi may contribute to the observed PEs. Network analysis showed that the numbers of positive correlations between fungal taxa and other microorganisms increased with the enhancement of the late PE intensity, suggesting that fungi and associated co-metabolisms may play key roles in late PEs in this study. Collectively, this study gives new insights into PE intensity and underlying microbial drivers of PE in lake sediments, and such knowledge is of great importance to understanding organic matter mineralization in lake ecosystems.</p>
Data from: Different effects of paternal trans-generational immune priming on survival and immunity in step and genetic offspring
Paternal trans-generational immune priming, whereby fathers provide immune protection to offspring, has been demonstrated in the red flour beetle Tribolium castaneum exposed to the insect pathogen Bacillus thuringiensis. It is currently unclear how such protection is transferred, as in contrast to mothers, fathers do not directly provide offspring with a large amount of substances. In addition to sperm, male flour beetles transfer seminal fluids in a spermatophore to females during copulation. Depending on whether paternal trans-generational immune priming is mediated by sperm or seminal fluids, it is expected to either affect only the genetic offspring of a male, or also their step offspring that are sired by another male. We therefore conducted a double-mating experiment and found that only the genetic offspring of an immune primed male show enhanced survival upon bacterial challenge, while phenoloxidase activity, an important insect immune trait, and the expression of the immune receptor PGRP were increased in all offspring. This indicates that information leading to enhanced survival upon pathogen exposure is transferred via sperm, and thus potentially constitutes an epigenetic effect, whereas substances transferred with the seminal fluid could have an additional influence on offspring immune traits and immunological alertness.
Data from: Litter carbon and nutrient chemistry control the magnitude of soil priming effect
1. Plant litter inputs can promote the decomposition of soil organic matter (OM) through the priming effect (PE). However, whereas leaf litter chemistry has long been identified as the primary driver of litter decomposition within biomes worldwide, little is known about how litter chemical traits influence the occurrence and strength of the PE. 2. Here, we studied the effects of 15 co-occurring C3 leaf litters of contrasting chemistry on C4 soil respiration by analyzing changes in 13C natural abundance during early and later stages of litter decomposition (up to 125 days). 3. Besides an apparent PE of 16% in the first three days, soil C respiration was increased by 24% on average with leaf litter addition in the initial stage of decomposition (426 d) and by 8% at later stages (27125 d). Most interestingly, soil PE related well to initial litter chemistry and the dominant factors influencing the magnitude of the PE changed with decomposition stage. In the early stage of decomposition, litter leachate C content and litter hemicellulose concentration were positively correlated with the strength of the PE, whereas tannin concentration was negatively associated with soil PE. Together, tannin and hemicellulose explained half of the observed variation in the PE (R2 = 0.58). In the later phase of decomposition, lignin and lignin:N ratios were negatively related to the PE, whereas Ca, K and Mg concentrations were positively related to the PE; lignin alone gave the best prediction of the PE (R2 = 0.58) at later decomposition stages. 4. Our findings provide evidence that the magnitude and direction of the PE is influenced by the chemistry of organic matter inputs and suggest that, as decomposition proceeds differently among litter of contrasting chemistry, litters can also have variable effect on soil PE through time. The predictive power of litter chemical traits on soil PE opens new perspectives for improving our mechanistic understanding of soil PE and improving our abilities to model soil C dynamics at variable scales.
Effect of Priming During Induction and Consolidations in Younger Acute Myeloid Leukemia (AML)
ClinicalTrials.gov study NCT00880243. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Effect of Mental Arithmetic Priming on Gait and Balance in Stroke
ClinicalTrials.gov study NCT07327814. IPD Sharing: YES. Countries: 0. Publications: 1.
Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies
ClinicalTrials.gov study NCT04764396. IPD Sharing: YES. Countries: 1. Publications: 0.
The Effect of Priming of Questionnaire Content on Grip Strength in Patients With Hand and Upper Extremity Illness
ClinicalTrials.gov study NCT02493127. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Litter quality and site characteristics interact to affect the response of priming effect to temperature in subtropical forests
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Deciphering linkages between microbial communities and priming effects in lake sediments with different salinity
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Data from: Litter carbon and nutrient chemistry control the magnitude of soil priming effect
Open the record for dataset details and reuse information.
Data from: Different effects of paternal trans-generational immune priming on survival and immunity in step and genetic offspring
Open the record for dataset details and reuse information.
Genotoxic effects of base and prime editing in human hematopoietic stem cells [BARseq_BaseE]
GEO Series GSE220753. Homo sapiens. 136 samples. Type: Other.
Genotoxic effects of base and prime editing in human hematopoietic stem cells [NHEJ_PrimeE]
GEO Series GSE220765. Homo sapiens. 25 samples. Type: Other.
Single guide RNA CRISPR /Cas(sg) editing 3 nucleotides and prime editing (pe) single nucleotide of CArG element in Tspan2 promoter effect on transcriptome in aortas
GEO Series GSE158388. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Cytokine Priming Enhances the Antifibrotic Effects of Mesenchymal Stromal Cells Conditioned Medium Via Fibrogenic Myofibroblasts Elimination and Extracellular Matrix Degradation.
GEO Series GSE266052. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Genotoxic effects of base and prime editing in human hematopoietic stem cells [NHEJ_BaseE]
GEO Series GSE220763. Homo sapiens. 362 samples. Type: Other.
The effect of MPO-ANCA on LPS-primed human monocytes
GEO Series GSE89153. Homo sapiens. 12 samples. Type: Expression profiling by array.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.