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382 results for “red cells”
Figure 1 in Blood cells and some hematological parameters of red drum (Linnaeus, 1766) in Vietnam
Figure 1. Erythrocytes of red drum. a - location L1, b - location L2, c - location L3. The red arrow indicates the deformed erythrocyte nuclear/uneven nuclear-matter distribution. The blue arrow indicates the slightly alkaline erythrocytes.
Thin blood smear images of red blood cells with rouleaux formation morphology and normal morphology
<p>This dataset contains images of thin blood smear with normal red blood cell morphology and rouleaux red blood cell morphology. Ethical approval with approval number: NHREC/17/03//2018 was obtained from Kano state ministry of health. Blood samples from 100 malaria infected patients were collected from Asiya Bayero pediatric hospital, kano state, Nigeria. Thick and thin blood smear slides were prepared using field stain. To ensure there was no bias in slide preparation, slides used for hospital diagnosis prepared under limited and constrained conditions were used as such types of slides represent the true reality of malaria diagnosis in less developed countries.Thin blood smear microscopy was performed by an expert microscopist and each slide was labeled according to the presence of Rouleaux formation or not among others. Out of 100 samples collected, 28 samples had rouleaux formation morphology.</p> <p>A 12MP iPhone 10 camera was attached to a microscope’s eyepiece. Pictures of different field of views for each slide were captured using the iPhone’s camera. For each slide, a minimum of 10 different field of views were captured. 616 images were captured for slides with rouleaux formation. To create a balanced dataset an equal number, 616 images were also captured for slides with normal morphology. To increase the size and variation of the dataset. 312 Digital images of thin blood smear slides with Giemsa staining collected from Murtala Muhammad specialist hospital were added. out of the 312 images, 156 had rouleaux RBC morphology and 156 had normal RBC morphology. Image capture was conducted in the morning, afternoon and evening and in different rooms with different lighting conditions to introduce diverse levels of illumination in the images The captured images from both hospitals had a size of 4032x3024 pixels. The background of the images were cropped to give a size 2500x2500 which were then sliced to give a final size of 750x750 pixels. The final data set consists of 12,356 thin blood smear images with rouleaux formation morphology and 12,356 thin blood smear images with normal red blood cell morphology. Different CNN architectures were trained for the binary classification of the dataset.</p>
Red Blood Cell RedTell Dataset
<p>The dataset contains microscopic images of red blood cells (RBCs) and consists of two parts:</p> <p>1. dse_data.zip</p> <p>This dataset includes brightfield images of healthy control individuals obtained in the scope of the CoMMiTMenT study. The images are annotated on a single cell level for segmentation and classification (discocyte-stomatocyte-echinocyte sequence) purposes. </p> <p>2. anemia_data.zip</p> <p>This dataset includes brightfield and fluorescent images of RBCs of sickle cell disease (SCD) patients from the MemSID study as well as of thalassemia patients and healthy controls from the CoMMiTMenT study.</p> <p>The CoMMiTMenT study was funded by the European Seventh Framework Program under grant agreement number 602121 (CoMMiTMenT) and from the European Union’s FP7 Programme. The study protocols were approved by the Medical Ethical Research Board of the University Medical Center Utrecht, the Netherlands, under reference code 15/426M and by the Ethical Committee of Clinical Investigations of Hospital Clinic, Spain (IDIBAPS) under reference code 2013/8436. The MemSID study was performed at the University hospital Zurich (#NCT02615847 at https://clinicaltrials.gov/). The trial protocol was approved by the Ethics committee of Canton Zurich (KEK-ZH 2015-0297).</p>
3D time-course iSIM dataset HeLa cells MitoTracker Red CMXRos
<p>2020-03-17</p> <p>Microscopy dataset:</p> <p>- Type: Fluorescence, 3D, time-course, iSIM Visitech, 100x Silicon NA 1.35 (65 nm x 65 nm x 300 nm xyz pixel sizes), 20s time interval</p> <p>- Cell type: HeLa, labelled with MitoTracker Red CMXRos</p> <p> </p> <p>Romain F. Laine, r.laine@ucl.ac.uk, MRC-LMCB, UCL, London, UK</p>
White Blood Cells with cytoplasm and surrounding red blood cells
<p>This dataset is taken from doi:10.17632/w7cvnmn4c5.1 and is used for segmentation of irregular shaped white blood cells in 2D. We also provide dataset for cytoplasm and we trained StarDist and UNET models to be applied in the VollSeg setting on this dataset.</p>
Red blood cell cytoskeleton tomography data
<p>1) WT-14_MinorClean.mat - Three-dimensional image of a red cell cytoskeleton obtained by cryoelectron tomography. Edges were removed by running the following commands in Matlab:</p> <p>load WT-7_MinorClean.mat;<br> [M, N, P] = size(v);<br> [NN, MM, PP] = meshgrid(1:N,1:M,1:P);<br> v( MM > 790) = 0;<br> v( PP < 12) = 0;<br> v( PP > 70) = 0;</p> <p>To binarize the image, we used a threshold of -40, i.e. each voxel containing an intensity value less than -40 was considered to be a part of the cytoskeleton.</p> <p>2) ActinFilamentMASKED_BIN.mat - Structure of actin protofilament from Protein Data Bank after masking and binning.</p> <p>3) coordsWT-14sk.mat - Positions of actin protofilaments identified inside the tomogram after template matching.</p>
Inferring whole-organism metabolic rate from red blood cells in birds
<p>Metabolic rate is a key ecological variable that quantifies the energy expenditure needed to fuel almost all biological processes in an organism. Metabolic rates are typically measured at the whole-organism level (woMR) with protocols that can elicit stress responses due to handling and confinement, potentially biasing resulting data. Improved, non-stressful methodology would be especially valuable for measures of field metabolic rate, which quantifies the energy expenditure of free-living individuals. Recently, techniques to measure cellular metabolic rate (cMR) in mitochondria of blood cells have become available, suggesting that blood-based cMR can be a proxy of organismal aerobic performance. Aerobic metabolism actually takes place in the mitochondria. Quantifying cMR from blood samples offers several advantages such as direct estimates of metabolism and minimized disturbance of individuals. To our knowledge, the hypothesis that blood-based cMR correlates with woMR has not yet been directly tested.</p> <p>We measured cMR in red blood cells of captive great tits (<i>Parus major</i>), first during their morning activity period and second after subjecting them to a 2.5 h day-time respirometry protocol to quantify woMR. We predicted cMR to decrease as individuals transitioned from an active to a resting state. In the two blood samples we also assessed circulating corticosterone concentrations to determine the perceived disturbance of individuals. From respirometry traces we extracted initial and final woMR measures to test for a predicted positive correlation with cMR measures, while accounting for corticosterone concentrations.</p> <p>Indeed, cMR declined from the first to the second measurement. Furthermore, woMR and cMR were positively related in individuals that had relatively low corticosterone concentrations and displayed little locomotor activity throughout respirometry. By contrast, woMR and cMR covaried negatively in birds that increased corticosterone concentrations and activity levels substantially.</p> <p>Our results show that red blood cell cMR represents a proxy for woMR when birds do not display signs of stress, i.e. either before increases in hormonal or behavioral parameters have occurred or after they have abated. This method represents a valuable tool for obtaining metabolic data repeatedly and in free-living individuals. Our findings also highlight the importance of accounting for individual stress responses when measuring metabolic rate at any level.</p> <p>Metabolic rate is a key ecological variable that quantifies the energy expenditure needed to fuel almost all biological processes in an organism. Metabolic rates are typically measured at the whole-organism level (woMR) with protocols that can elicit stress responses due to handling and confinement, potentially biasing resulting data. Improved, non-stressful methodology would be especially valuable for measures of field metabolic rate, which quantifies the energy expenditure of free-living individuals. Recently, techniques to measure cellular metabolic rate (cMR) in mitochondria of blood cells have become available, suggesting that blood-based cMR can be a proxy of organismal aerobic performance. Aerobic metabolism actually takes place in the mitochondria. Quantifying cMR from blood samples offers several advantages such as direct estimates of metabolism and minimized disturbance of individuals. To our knowledge, the hypothesis that blood-based cMR correlates with woMR has not yet been directly tested.</p> <p>We measured cMR in red blood cells of captive great tits (<i>Parus major</i>), first during their morning activity period and second after subjecting them to a 2.5 h day-time respirometry protocol to quantify woMR. We predicted cMR to decrease as individuals transitioned from an active to a resting state. In the two blood samples we also assessed circulating corticosterone concentrations to determine the perceived disturbance of individuals. From respirometry traces we extracted initial and final woMR measures to test for a predicted positive correlation with cMR measures, while accounting for corticosterone concentrations.</p> <p>Indeed, cMR declined from the first to the second measurement. Furthermore, woMR and cMR were positively related in individuals that had relatively low corticosterone concentrations and displayed little locomotor activity throughout respirometry. By contrast, woMR and cMR covaried negatively in birds that increased corticosterone concentrations and activity levels substantially.</p> <p>Our results show that red blood cell cMR represents a proxy for woMR when birds do not display signs of stress, i.e. either before increases in hormonal or behavioral parameters have occurred or after they have abated. This method represents a valuable tool for obtaining metabolic data repeatedly and in free-living individuals. Our findings also highlight the importance of accounting for individual stress responses when measuring metabolic rate at any level.</p>
Standard Issue Transfusion Versus Fresher Red Blood Cell Use in Intensive Care- A Randomised Controlled Trial
ClinicalTrials.gov study NCT01638416. IPD Sharing: UNDECIDED. Countries: 5. Publications: 4.
Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs
ClinicalTrials.gov study NCT00957931. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of Fluid Restriction Policy in Reducing the Use of Red Cells in Cardiac Surgery
ClinicalTrials.gov study NCT00600704. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Duration of Red Blood Cell Storage Prior to Transfusion
ClinicalTrials.gov study NCT02087514. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden
ClinicalTrials.gov study NCT03263091. IPD Sharing: NO. Countries: 16. Publications: 1.
Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia
ClinicalTrials.gov study NCT00229619. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality
ClinicalTrials.gov study NCT02889133. IPD Sharing: NO. Countries: 1. Publications: 3.
Hypoxic Red Blood Cells for Burns and Hematological Malignancies at Haukeland University Hospital
ClinicalTrials.gov study NCT05549232. IPD Sharing: NO. Countries: 1. Publications: 3.
Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants
ClinicalTrials.gov study NCT03169881. IPD Sharing: YES. Countries: 1. Publications: 4.
Fresh Versus Old Red Blood Cells for Transfusion
ClinicalTrials.gov study NCT01319552. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Red Blood Cell Survival on a Commonly Used Diabetes Lab Test-HbA1c
ClinicalTrials.gov study NCT01204216. IPD Sharing: Not stated. Countries: 1. Publications: 2.
VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?
ClinicalTrials.gov study NCT02918851. IPD Sharing: NO. Countries: 1. Publications: 1.
The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Du
ClinicalTrials.gov study NCT01566695. IPD Sharing: Not stated. Countries: 23. Publications: 2.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.