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140 results for “resting state”
BRAIN Journal-Isolating the Norepinephrine Pathway Comparing Lithium in Bipolar Patients to SSRIs in Depressive Patients-Figure 2. Resting state neuroimaging findings illustrating the action of Lithium following whole brain
<p>The axial, saggital, and coronal MRI activation maps illustrate increased delta frequency band neuronal activity in the 46 patients<br> diagnosed with Bipolar Affective Disorder compared to 32 female patients diagnosed with Major Depressive Disorder of Depressive<br> Episode. The Yellow/Orange shades indicate increased neuronal activity in the right Superior Frontal Gyrus (t=0.920, p=0.05060,<br> BA 6, MNI X=20, Y=0, Z=70) and in the right Cingulate Gyrus (t=0.0846, BA 24, MNI X= 5, Y=0, Z=51). Structural anatomy is<br> shown in grey scale (A – anterior; S – superior; P – posterior; L – left; R – right).</p>
BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 100 Schizophrenia Patients to 48 Patients with Major Depression -Figure 2. Resting State neuroimaging findings illustrating the action of atypical antipsychotics on postsynaptic dopamine D2
<p>Contrastingly, the results of the one-hundred males and females diagnosed with<br> Schizophrenia compared to the thirty-two females diagnosed with Major Depressive Disorder or<br> Depressive Episodes. The one-hundred male and female Schizophrenia patients had an average age<br> of 32-years-old and a Standard Deviation of 11.8-years. Whereas, the Depressive Episode and<br> Major Depressive Disorder females had an average age of 50-years old and a Standard Deviation of<br> 11.7-years. The statistically significant neuroimaging results identified the Delta (1.5–6 Hz)<br> frequency band at the neuroanatomical location of the region of the Superior Frontal Gyrus<br> (p=0.007; t=2.08, BA 10, X=25, Y=55, Z=30) with greater neuronal oscillations and synchrony in<br> the one-hundred males and females diagnosed with Schizophrenia than the thirty-two females<br> diagnosed with Depressive Episodes and Major Depressive Disorder.</p>
BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls-Figure 2: All axial slices of sLORETA imaging results of Resting State EEG Supra-Threshold Voxels in both the Parahippocampal (limbic) and Fusiform (temporal) Gyri illustrating decreased neuronal activity in the Anorexia Nervosa patients.
<p>Results from the sLORETA imaging indicates decreased neuronal activation within the Left<br> Fusiform Gyrus located in the Temporal lobe and Parrahippocampal gyrus, which is located in the<br> Limbic Lobe (Table 1). This correlates with other fMRI findings where patients with early onset<br> AN have exhibited reduced unilateral blood flow in the temporal lobe. The Parahippocampal and<br> Fusiform Gyri are centers that process emotions. Previous studies in which these regions have<br> shown activation involve women that have distorted perceptions of their bodies from a cognitive<br> perspective (Santel et al., 2006). It is apparent from our findings that the Fusiform Gyrus may play<br> a vital role in the processing of visual appearance of the human body. There is also a correlation<br> with the somatosensory limbic pathway in the limbic lobe, due to the similarity of function.</p>
BRAIN Journal-Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls-Figure 1: sLORETA imaging results of Resting State EEG Supra-Threshold Voxels in both the Parahippocampal (limbic) and Fusiform (temporal) Gyri illustrating decreased neuronal activity in the Anorexia Nervosa patients relative to Control participants
<p>The findings of the sLORETA analysis indicated that, the difference is statistically<br> significant (p=0.03) using a one-tailed t-test: Anorexia > Controls. The brains of the patients with<br> Anorexia Nervosa illustrated decreased neuronal activity in the Left Fusiform Gyrus and the Left<br> Parahippocampal Gyrus (p=0.03) in the resting-state brains when Anorexia Patients were sitting for<br> 3min, as compared to the Controls sitting for 3minutes.</p>
BRAIN Journal-Isolating the Norepinephrine Pathway Comparing Lithium in Bipolar Patients to SSRIs in Depressive Patients-Figure 1. Resting state neuroimaging findings illustrating the action of Lithium following whole brain
<p>The axial, saggital, and coronal MRI activation maps illustrate neuronal activity of 46 patients diagnosed with Bipolar Affective<br> Disorder compared to 16 male patients diagnosed with Major Depressive Disorder of Depressive Episode. The Yellow/Orange<br> shades indicate increased neuronal activity in the right Superior Temporal Gyrus (t=1.403, p=0.00780, BA 41, MNI X=45, Y= -35,<br> Z=10) with activation also in the Fusiform Gyrus (t=1.26, BA 20, MNI X= 45, Y= -35, Z=10), the Parahippocampal Gyrus (t=1.29,<br> BA 36, MNI X=45, Y= -35, Z=10). (b) Increased neuronal activity in the Cingulate Gyrus (t=1.06, BA 32, MNI X=45, Y= -35,<br> Z=10). Structural anatomy is shown in grey scale (A – anterior; S – superior; P – posterior; L – left; R – right).</p>
The dataset of article "Early Detection of Cognitive Impairment in End-Stage Renal Disease Patients Undergoing Hemodialysis: Insights from Resting-State Functional Connectivity Analysis"
<p>This is a file as dataset of the article "Early Detection of Cognitive Impairment in End-Stage Renal Disease Patients Undergoing Hemodialysis: Insights from Resting-State Functional Connectivity Analysis".</p> <p>It includes fMRI brain imaging data of subjects included in the case group (ESRD group) and healthy control group (HC group).</p>
Dataset from "Power Spectral Density-Based Resting-State EEG Classification of First-Episode Psychosis"
<p>Denoised and Preprocessed data from <em>EEG: First Episode Psychosis vs. Control Resting Task 1</em> as described in <em>Power Spectral Density-Based Resting-State EEG Classification of First-Episode Psychosis.</em></p> <p>Original dataset: <a href="https://doi.org/10.18112/openneuro.ds003944.v1.0.1">doi:10.18112/openneuro.ds003944.v1.0.1</a></p>
Cortex-wide neural dynamics predict behavioral states and provide a neural basis for resting-state dynamic functional connectivity
<p><strong>GENERAL INFORMATION</strong></p> <p>This data is described in the following publication: </p> <p><strong>Cortex-wide neural dynamics predict behavioral states and provide a neural basis for resting-state dynamic functional connectivity</strong>, Somayeh Shahsavarani<sup>1,2,5</sup>, David N. Thibodeaux<sup>1,5</sup>, Weihao Xu<sup>1</sup>, Sharon H. Kim<sup>1</sup>, Fatema Lodgher<sup>1</sup>, Chinwendu Nwokeabia<sup>1</sup>, Morgan Cambareri<sup>1</sup>, Alexis J. Yagielski<sup>1</sup>, Hanzhi T. Zhao<sup>1</sup>, Daniel A. Handwerker<sup>2</sup>, Javier Gonzalez-Castillo<sup>2</sup>, Peter A. Bandettini<sup>2,3</sup>, Elizabeth M. C. Hillman<sup>1,4,6,*</sup> Cell Reports (2023): <a href="https://doi.org/10.1016/j.celrep.2023.112527">https://doi.org/10.1016/j.celrep.2023.112527</a></p> <p><br> 1. Mortimer B. Zuckerman Mind Brain Behavior Institute and Department of Biomedical Engineering, Columbia University, New York, NY, USA<br> 2. Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA<br> 3. Functional MRI Core Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA<br> 4. Department of Radiology, Columbia University Irving Medical Center, New York, NY, USA<br> 5. These authors contributed equally<br> 6. Lead contact<br> *Correspondence: elizabeth.hillman@columbia.edu</p> <p>Preprocessing and analysis code that generated / can be used with this data is posted at: <br> GitHub: <a href="https://doi.org/10.5281/zenodo.7860561">https://doi.org/10.5281/zenodo.7860561</a></p> <p><strong>DATA OVERVIEW </strong></p> <p>This dataset comprises simultaneous neuronal and hemodynamic data collected using wide-field optical mapping (WFOM) techniques. The data were obtained from head-fixed mice that were allowed to behave spontaneously without any external stimulation. For more detail, please refer to the Readme file.</p>
Resting-state fMRI data for locating causal hubs of memory consolidation in spontaneous brain network
<p>The mouse fMRI data for the paper "<strong>Locating causal hubs of memory consolidation in spontaneous brain network in male mice</strong>"<strong> </strong>published in <strong>Nature Communications </strong>(DOI: 10.1038/s41467-023-41024-z)<strong>. </strong>This includes longitudinal resting-state fMRI data in mice after behavioural training for 1-Day or 5-Day Active Place Avoidance (APA) task, acquired at post-training day 1 and day 8. Due to the large datasets, each group has been packed into several 2GB zip files. They need to be downloaded into the same folder and unpacked together (e.g. 1-Day APA Post training day 1 has five zip files starting with "1DAPA_PostDay1"). The structural and EPI templates and the ROI labels in the AMBMC atlas space are provided in the AMBMC_label.zip. </p>
Data from: Genuine cross-frequency coupling networks in human resting-state electrophysiological recordings
Open the record for dataset details and reuse information.
Linking the microarchitecture of neurotransmitter systems to large-scale MEG resting state networks
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Vanadium nitrogenase - anomalous maps for resting and turnover states
<p>The data set contains anomalous difference electron density maps (in CCP4 format) for two published crystal structures of <em>Azotobacter vinelandii</em> vanadium-dependent nitrogenase. These are:</p> <p>1. VFe protein - resting state. <strong>PDB-ID 5N6Y</strong>. Sippel <em>et al. </em>(2017) <em><strong>Nature Chem. Biol.</strong></em> 13, 956-960. DOI: 10.1038/Nchembio.2428</p> <p>2. VFe protein - turnover state. <strong>PDB-ID 6FEA</strong>. Sippel et al. (2018) <em><strong>Science</strong></em> 359, 1484-1489. DOI: 10.1126/science.aar2765</p> <p>For each deposition, the maps provided are calculated with anomalous differences as Fourier coefficients, to 1.9 Å or 2.0 Å resoution, respectively. Depending on energies of data collection, these maps were used to visualize:</p> <p>12398 eV - anomalous contirbution of iron ions</p> <p>7000 eV - anomalous contribution of sulfur atoms (with strong contribution of V)</p> <p>6200 eV - improved signal for S/Fe and S/V, respectively (not shown in publications).</p>
Data from: The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation
<p>Included are raw neuroimaging and preprocessed neural recording data from "The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation" (see Related Works section; citation will be updated after publication). Please cite this paper if you use any of these data. Refer to the linked github repository for associated code.</p> <p>Neuroimaging data is organized in BIDS format and saved as NIfTI files. We used MION (monocrystalline iron oxide nanoparticle) as a contrast agent. Functional resting state files can be found in the 'func' folder for each imaging session. The final six runs are resting state data (the first two/three are short EPI sequences used to test that MION is present in the brain; all resting state data used in our analyses consist of 300 volumes). The first three of these six runs consist of baseline data with no drug treatment. Four through six are resting state data recorded after I.M. injection of vehicle (2% DMSO in saline), dechloroclozapine (DCZ) or clozapine-N-oxide (CNO). </p> <p>Neural recording data is separated into LFP data, organized by folder, and putative single units, organized the 'Sorted neurons' folder. LFP data folders are named by subject's intial and date of recording. Single units are labeled according to this same system. All data are stored in .mat format and can be opened in MATLAB. KB2.mat files store timing information: the first event in the KBD2 file indicates the start of baseline, pre-injection data acquisition, and the second event indicates the start of post-injection treatment data. The KB3.mat files contains the timing information of the drug injection. As with the fMRI data, we treated animals with I.M. injection of vehicle, DCZ, or CNO. </p> <p>Treatment information for both modalities is as follows. Neuroimaging: 2020/03/16 Animal L DCZ 1; 2020/05/27 Animal H vehicle 1; 2020/06/01 Animal L vehicle 1; 2020/06/08 Animal H DCZ 1; 2020/06/22 Animal L DCZ 2; 2020/06/24 Animal H vehicle 2; 2020/07/06 Animal L vehicle 2; 2020/07/08 Animal H DCZ 2; 2021/10/25 Animal L CNO; 2022/01/13 Animal H CNO. Neural recordings: 2022/04/14 Animal H DCZ 1; 2022/04/21 Animal H vehicle 1; 2022/05/12 Animal H DCZ 2; 2022/05/24 Animal H vehicle 2; 2022/06/03 Animal H CNO; 2022/08/18 Animal L vehicle 1; 2022/08/25 Animal L DCZ 1; 2022/09/01 Animal L DCZ 2; 2022/09/08 Animal L vehicle 2; 2022/09/22 Animal L CNO.</p>
PHIME Pilot resting state fMRI study
<p>Resting state functional Magnetic Resonance Imaging (fMRI) data for 14 adolescents (12-18 years) that were part of a pilot neuroimaging study on manganese exposure and brain development in Northern Italy. Participants are part of the Public Health Impact of Manganese Exposure (PHIME) study.</p> <p>Data include a 10-minute resting state fMRI scan (repetition time: 2500 ms) and an anatomical scan (3D MPRAGE) for each subject.</p>
Coordinates activities of retrosplenial ensembles during resting-state encode spatial landmarks. Part 1 of 2
<p>The brain likely uses off-line periods to consolidate recent memories. One hypothesis holds that the hippocampal output provides a unique, global linking or 'index' code for each memory, and that this code is stored in the cortex in association with locally encoded attributes of each memory. Activation of the index code is hypothesized to evoke coordinated memory trace reactivation thus facilitating consolidation. Retrosplenial cortex (RSC) is a major recipient of hippocampal outflow and we have described populations of neurons there with sparse and orthogonal coding characteristics that resemble hippocampal 'place' cells, and whose expression depends on an intact hippocampus. Using two-photon Ca<sup>2+</sup> imaging, we recorded ensembles of neurons in the RSC during periods of immobility before and after active running on a familiar linear treadmill track. Synchronous bursting of distinct groups of neurons occurred during rest both prior to and after running. In the second rest epoch, these patterns were associated with the locations of tactile landmarks and reward. Complementing established views on the functions of the RSC, our findings indicate that the structure is involved with processing landmark information during rest.</p>
Coordinates activities of retrosplenial ensembles during resting-state encode spatial landmarks. Part 2 of 2
<p>The brain likely uses off-line periods to consolidate recent memories. One hypothesis holds that the hippocampal output provides a unique, global linking or 'index' code for each memory, and that this code is stored in the cortex in association with locally encoded attributes of each memory. Activation of the index code is hypothesized to evoke coordinated memory trace reactivation thus facilitating consolidation. Retrosplenial cortex (RSC) is a major recipient of hippocampal outflow and we have described populations of neurons there with sparse and orthogonal coding characteristics that resemble hippocampal 'place' cells, and whose expression depends on an intact hippocampus. Using two-photon Ca<sup>2+</sup> imaging, we recorded ensembles of neurons in the RSC during periods of immobility before and after active running on a familiar linear treadmill track. Synchronous bursting of distinct groups of neurons occurred during rest both prior to and after running. In the second rest epoch, these patterns were associated with the locations of tactile landmarks and reward. Complementing established views on the functions of the RSC, our findings indicate that the structure is involved with processing landmark information during rest.</p>
Multi-echo resting-state fMRI networks of healthy volunteers
<p>The dataset contains the resting-state networks of 16 healthy volunteers following multi-echo combination methods: 1) optimal combination 2) tSNR-weighted combination 3) tCNR-weighted combination (PAID method) 4) second echo only (single-echo) After echo combination by one of the methods (or the second echo) 30 independent components were extracted using group ICA and dual regression.</p> <p>Image format: Gunzipped NIfTI (.nii.gz)</p> <p>Time-series format: text file (.txt)</p> <p>The structure of the uploaded folder:</p> <p>- Layer 1: PilmeyerEtAl_ICA_maps_and_timeseries - main folder</p> <p>- Layer 2 (combination method): OC - optimal combination, SE- second echo, tCNR - temporal contrast-to-noise, tSNR - temporal signal-to-noise</p> <p>- Layer 3: groupICA_desc-XX - contains the group ICA maps and time-series before dual regression, sub-YY - folders for each of the 16 subjects</p> <p>- Layer 4: sub-YY_desc_XX - contains the individual extracted ICA maps and time-series</p> <p> </p> <p> </p> <p> </p>
Resting-state functional connectivity matrices of various unconscious, psychedelic, and neuropsychiatric states.
<p>Functional connectivity matrices of various unconscious, psychedelic, and neuropsychiatric states.</p> <p>Conditions include:</p> <p>N2 Sleep</p> <p>Subaneshesthetic ketamine</p> <p>Deep sedation with propofol</p> <p>Surgical-level propofol anesthesia</p> <p>LSD</p> <p>N2O </p> <p>ADHD</p> <p>Bipolar disorder</p> <p>Schizophrenia</p> <p>Functional connectivity matrices with and without global signal regression are both included.</p>
Resting-State Neural Connectivity in Patients With Subjective Tinnitus Without Bother
ClinicalTrials.gov study NCT01049828. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Resting State Changes Following Theta Burst Stimulation
ClinicalTrials.gov study NCT05322239. IPD Sharing: YES. Countries: 1. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.