Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
897
datasets available to search
ShareScore release 0.9.0
Dataset results
897 results for “Therapeutic targets”
Cyclin-dependent kinase 9 is a therapeutic target for anti-TNF resistant inflammatory bowel disease
GEO Series GSE172372. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Oxidative phosphorylation is a pivotal therapeutic target of fibrodysplasia ossificans progressiva
GEO Series GSE220725. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
The early expansion of a defective NKG2Apos/CD56dim/CD16neg NK cell subset represents a therapeutic target in haploidentical HSCT
GEO Series GSE107021. Homo sapiens. 15 samples. Type: Expression profiling by array.
The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma
GEO Series GSE287721. Homo sapiens. 2 samples. Type: Other.
A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration [bulk RNA-seq]
GEO Series GSE249229. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II
GEO Series GSE98786. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Identification of therapeutic targets of the hijacked super-enhancer complex in EVI1-rearranged leukemia
GEO Series GSE153307. Homo sapiens. 21 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.
Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor SGI-110 in Hepatocellular Carcinoma Cells [methylation]
GEO Series GSE105066. Homo sapiens. 34 samples. Type: Methylation profiling by array.
Negative feedback enables oncogenic signaling in pre-B cells and represents a therapeutic target in acute lymphoblastic leukemia
GEO Series GSE58739. Homo sapiens. 2 samples. Type: Genome variation profiling by high throughput sequencing.
Mitochondria as key therapeutic targets for the treatment of corneal fibrosis
GEO Series GSE231796. Felis catus. 25 samples. Type: Expression profiling by high throughput sequencing.
HNF4α is a therapeutic target that links AMPK to WNT signaling in early-stage gastric cancer
GEO Series GSE63288. Homo sapiens. 44 samples. Type: Expression profiling by high throughput sequencing.
Proteogenomic analysis reveals a compendium of therapeutic targets for treatment-resistant subtypes of locally advanced cervical cancers
GEO Series GSE279998. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Burkitt Lymphoma Pathogenesis and Therapeutic Targets from Structural and Functional Genomics
GEO Series GSE35163. Homo sapiens. 32 samples. Type: Expression profiling by array.
The P2Y14/UDP-Glucose pathway is a therapeutic target for ischemic AKI
GEO Series GSE144522. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation
GEO Series GSE227114. Homo sapiens. 6 samples. Type: Expression profiling by array.
FSP1 is a predictive biomarker of osteosarcoma cells' susceptibility to ferroptotic cell death and a potential therapeutic target.
Open the record for dataset details and reuse information.
Unveiling Therapeutic Targets and Immunological Insights in Glioblastoma Through Analysis of Glioma-Associated Mesenchymal Stem Cells
<p>To analyze the binding affinities and interaction modes between the drug candidates and their targets, we employed the Autodock Vina software [21]. Molecular structures of the candidate drugs and targets of hub genes were retrieved from Pubchem (https://pubchem.ncbi.nlm.nih.gov/) and Protein Data Bank database (http://www.rcsb.org/), respectively. <span>In the analysis of docking, the files for all proteins and molecules were converted to PDBQT format. Water molecules were removed and polar hydrogen atoms were added. The grid box was positioned at the center to encompass the protein domain, allowing for unrestricted movement of molecules.</span></p>
JNK signaling provides a novel therapeutic target for Rett syndrome
<p>Raw data available at this link: https://zenodo.org/record/5608558#.YXrZnsZabJ8</p>
Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)
ClinicalTrials.gov study NCT01354613. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma
ClinicalTrials.gov study NCT06959979. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.