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412
datasets available to search
ShareScore release 0.7.1
Dataset results
412 results for “genetic risk”
Genetic Markers of CHD Risk in Men and Women
ClinicalTrials.gov study NCT00090454. IPD Sharing: Not stated. Countries: 0. Publications: 0.
HYPGENE-Genetics Fitness Obesity & Risk of Hypertension
ClinicalTrials.gov study NCT00083811. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Genetic Epidemiology of CVD Risk Factors
ClinicalTrials.gov study NCT00053521. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Transcriptome response of mouse mammary gland from age 12 to 30 months of age in Esr1 and CYP19A1 genetically engineered mouse models of breast cancer risk in the presence and absence of transgene ind
GEO Series GSE201767. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes
GEO Series GSE167250. Homo sapiens. 36 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Transcriptome response to anti-hormonals in Esr1 and CYP19A1 genetically engineered mouse models of breast cancer risk during reproductive senescence
GEO Series GSE201326. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions [H3K4me3]
GEO Series GSE261637. Homo sapiens. 49 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Endothelial mutagenesis screen identifies genetic risk factors in the development vascular anomalies
GEO Series GSE137097. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Endothelial mutagenesis screen identifies genetic risk factors in the development vascular anomalies [adipose]
GEO Series GSE137095. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Endothelial mutagenesis screen identifies genetic risk factors in the development vascular anomalies [muscle]
GEO Series GSE137096. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Comparison of Long-Term Oncological Results in Young Women with Breast Cancer between BRCA-Mutation Carriers Versus Non-Carriers: How Tumor and Genetic Risk Factors Influence the Clinical Prognosis"
<p>This record contains raw data related to article "Comparison of Long-Term Oncological Results in Young Women with Breast Cancer between BRCA-Mutation Carriers Versus Non-Carriers: How Tumor and Genetic Risk Factors Influence the Clinical Prognosis"</p><p><strong>Abstract</strong></p><p><strong>Background: </strong>Breast cancer (BC) is very uncommon in young women (YW) and it is unclear whether a BRCA mutation has prognostic implications. Our aim was to evaluate the characteristics of YW with BC by comparing the long-term oncological results between BRCA-mutation carriers and non-carriers.</p><p><strong>Methods: </strong>We retrospectively reviewed all the consecutive YW (aged 18-40 years) diagnosed with BC. Endpoints were disease-free survival (DFS), distant disease-free survival (DDFS), and overall survival (OS).</p><p><strong>Results: </strong>63 YW with a BRCA mutation were compared with 339 YW without BRCA mutation. BRCA-mutation carriers were younger (60.3% versus 34.8% if age ≤ 35 years, <i>p</i> = 0.001) and presented with more aggressive tumors (66.7% versus 40.7% if G3, <i>p</i> = 0.001; 57.2% versus 12.4% if biological subtype triple-negative, <i>p</i> = 0.001; 73.0% versus 39.2% if Ki67 ≥ 25%, <i>p</i> = 0.001). Non-carriers presented significantly better DFS, DDFS, and OS compared with BRCA-mutation carriers. Neoadjuvant chemotherapy was found to be an independent protective factor for OS in BRCA-mutation carriers.</p><p><strong>Conclusions: </strong>BC is more likely to present at a younger age (≤ 35 years) and with more aggressive characteristics (G3, triple-negative, Ki67 ≥ 25%) in YW with BRCA mutation compared with their non-mutated counterparts. Young BRCA-mutation carriers showed a poorer prognosis in terms of recurrence and survival compared with non-carriers. The implementation of neoadjuvant chemotherapy may improve survival in YW with BC and BRCA mutation.</p>
MTF1 genetic variants (rs28411034 and rs3748682) are associated with lung cancer risk
<p>The genotyping of<strong><em> </em></strong><em>MTF1</em> SNPs (rs473279, rs28411034, rs28411352, and rs3748682) was identified by the Agena MassARRAY system among 670 healthy controls and 670 patients with LC.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.