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453
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ShareScore release 0.9.0
Dataset results
453 results for “Idiopathic pulmonary fibrosis”
Increased Cell Surface Fas Expression is Necessary to Sensitize Lung Fibroblasts to Fas Ligation-Induced Apoptosis: Implications for Fibroblast Accumulation in Idiopathic Pulmonary Fibrosis.
GEO Series GSE26594. Homo sapiens. 6 samples. Type: Expression profiling by array.
Regulation and role of the pro-apoptotic transcription factor CHOP in Idiopathic Pulmonary Fibrosis
GEO Series GSE87298. Mus musculus. 102 samples. Type: Expression profiling by array.
Validated Gene Expression Signatures of Idiopathic Pulmonary Fibrosis
GEO Series GSE24206. Homo sapiens. 23 samples. Type: Expression profiling by array.
Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis [ChIP-seq]
GEO Series GSE129085. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA sequencing of gene expression in fibroblasts derived from idiopathic pulmonary fibrosis and control lungs
GEO Series GSE185492. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiles of ageing human pulmonary blood vessel endothelial cells after their exposure to human serum from healthy donors and idiopathic pulmonary fibrosis patients
GEO Series GSE248091. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post
GEO Series GSE264196. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Disease-specific transcriptomic changes induced by NFκB inhibition in idiopathic pulmonary fibrosis
GEO Series GSE188464. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Senescent lung fibroblasts in idiopathic pulmonary fibrosis facilitate non-small cell lung cancer progression by secreting exosomal MMP1
GEO Series GSE279637. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of knockdown of junctional genes JUP and PLEC on Small Airway Epithelial Cells (SAECs) in the context of epithelial desquamation in distal bronchioles of Idiopathic Pulmonary fibrosis (IPF) pa
GEO Series GSE267943. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Targeting ATP12A, a non-gastric proton pump alpha subunit, for idiopathic pulmonary fibrosis treatment
GEO Series GSE205849. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA-Seq of fibroblasts derived from one patient with idiopathic pulmonary fibrosis.
GEO Series GSE220743. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Integrin/CD44-Targeted Liposomal Co-Delivery of Nintedanib and Dexamethasone for Acute Exacerbation of Idiopathic Pulmonary Fibrosis
GEO Series GSE303579. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomics-based Screening of Repurposing Drug for Idiopathic Pulmonary Fibrosis
GEO Series GSE291190. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome sequencing of lncRNAs, circRNAs, miRNAs, mRNAs and interaction network constructing in acute exacerbation of idiopathic pulmonary fibrosis [microarray]
GEO Series GSE222065. Homo sapiens. 10 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis
GEO Series GSE305464. Homo sapiens. 94 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article " PTX3 Regulation of Inflammation, Hemostatic Response, Tissue Repair, and Resolution of Fibrosis Favors a Role in Limiting Idiopathic Pulmonary Fibrosis."
<p>This record contains data related to article "PTX3 Regulation of Inflammation, Hemostatic Response, Tissue Repair, and Resolution of Fibrosis Favors a Role in Limiting Idiopathic Pulmonary Fibrosis."</p> <p>PTX3 is a soluble pattern recognition molecule (PRM) belonging to the humoral innate immune system, rapidly produced at inflammatory sites by phagocytes and stromal cells in response to infection or tissue injury. PTX3 interacts with microbial moieties and selected pathogens, with molecules of the complement and hemostatic systems, and with extracellular matrix (ECM) components. In wound sites, PTX3 interacts with fibrin and plasminogen and favors a timely removal of fibrin-rich ECM for an efficient tissue repair. Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive interstitial lung disease of unknown origin, associated with excessive ECM deposition affecting tissue architecture, with irreversible loss of lung function and impact on the patient's life quality. Maccarinelli et al. recently demonstrated a protective role of PTX3 using the bleomycin (BLM)-induced experimental model of lung fibrosis, in line with the reported role of PTX3 in tissue repair. However, the mechanisms and therapeutic potential of PTX3 in IPF remained to be investigated. Herein, we provide new insights on the possible role of PTX3 in the development of IPF and BLM-induced lung fibrosis. In mice, PTX3-deficiency was associated with worsening of the disease and with impaired fibrin removal and subsequently increased collagen deposition. In IPF patients, microarray data indicated a down-regulation of PTX3 expression, thus suggesting a potential rational underlying the development of disease. Therefore, we provide new insights for considering PTX3 as a possible target molecule underlying therapeutic intervention in IPF.</p>
Comprehensive gene expression of fibroblasts from idiopathic pulmonary fibrosis patients
GEO Series GSE209929. Homo sapiens. 6 samples. Type: Expression profiling by array.
Identification of Whole Blood Gene Expression Signature to Predict the Therapeutic Effect of Nintedanib in Idiopathic Pulmonary Fibrosis
GEO Series GSE215274. Homo sapiens. 177 samples. Type: Expression profiling by high throughput sequencing.
FOXO3 regulates Smad3 and Smad7 through SPON1 circular RNA to inhibit idiopathic pulmonary fibrosis
GEO Series GSE183750. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.