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443
datasets available to search
ShareScore release 0.9.0
Dataset results
443 results for “Metabolic Reprogramming”
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis
GEO Series GSE265830. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor
GEO Series GSE248283. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Dux promotes metabolism-lactylation-MET cascaded network during early iPSC reprogramming with Brg1 as the histone lactylation reader
GEO Series GSE251642. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Methionine starvation caused reprogrammed metabolism in Streptococcus pneumoniae
GEO Series GSE184094. Streptococcus pneumoniae. 4 samples. Type: Expression profiling by high throughput sequencing.
SIRT1-FOXO3 Pathway reprograms fatty acid metabolism to Mitigate Ferroptosis and Fibrosis [ChIP-seq]
GEO Series GSE292755. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
BATF orchestrates the functional specification and metabolic reprogramming in Treg cells
GEO Series GSE149197. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Environmental monobutyl phthalate exposure promotes liver cancer via reprogramming cholesterol metabolism and activation of the IRE1α-XBP1s pathway
GEO Series GSE248562. Homo sapiens. 25 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
SMARCA5 links histone lactylation to metabolic reprogramming and immune evasion [ATAC-seq]
GEO Series GSE307047. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MYC couples SWI/SNF and metabolic reprogramming to sustain minimal residual disease in mTORC1-activated cancer cells [CUT&RUN, ATAC-seq]
GEO Series GSE270774. Homo sapiens; Mus musculus. 32 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
25-Hydroxycholesterol inhibits hantavirus infection through reprogramming cholesterol metabolism and suggest statins as candidate hantavirus inhibitors
GEO Series GSE252127. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Platelets Transfer Aldolase via Extracellular Vesicles to Facilitate the Metabolic Reprogramming of Kupffer Cells in Acute Liver Injury
GEO Series GSE274627. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Reprograming of Glucose Metabolism by Zerumbone Suppresses Hepatocarcinogenesis
GEO Series GSE106855. Homo sapiens. 4 samples. Type: Expression profiling by array.
Metabolic Reprogramming of Iron Endows the Function of ISCA2-TET Interaction During Peri-implantation Development
GEO Series GSE275340. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Hypoxia-induced cysteine metabolism reprogramming are crucial for the tumorigenesis of colorectal cancer.
GEO Series GSE223120. Homo sapiens. 52 samples. Type: Expression profiling by high throughput sequencing.
Metabolic reprogramming in astrocytes prevents neuronal death through a UCHL1/PFKFB3/H4K8la positive feedback loop
GEO Series GSE266984. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Dux promotes metabolism-lactylation-MET cascaded network during early iPSC reprogramming with Brg1 as the histone lactylation reader [Cut & Tag]
GEO Series GSE251641. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Dataset related to article "Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer "
<p>This record contains raw data related to article “Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer"</p> <p>Although chemotherapeutic agents have been used for decades, the mechanisms of action, mechanisms of resistance, and the best treatment schedule remain elusive. Mitomycin C (MMC) is the gold standard treatment for non-muscle-invasive bladder cancer (NMIBC). However, it is effective only in a subset of patients, suggesting that, aside from cytotoxicity, other mechanisms could be involved in mediating the success of the treatment. Here, we showed that MMC promotes immunogenic cell death (ICD) and in vivo tumor protection. MMC-induced ICD relied on metabolic reprogramming of tumor cells toward increased oxidative phosphorylation. This favored increased mitochondrial permeability leading to the cytoplasmic release of mitochondrial DNA, which activated the inflammasome for efficient IL-1β (interleukin-1β) secretion that promoted dendritic cell maturation. Resistance to ICD was associated with mitochondrial dysfunction related to low abundance of complex I of the respiratory chain. Analysis of complex I in patient tumors indicated that low abundance of this mitochondrial complex was associated with recurrence incidence after chemotherapy in patients with NMIBC. The identification of mitochondria-mediated ICD as a mechanism of action of MMC offers opportunities to optimize bladder cancer management and provides potential markers of treatment efficacy that could be used for patient stratification.</p>
LIX1L aggravates NASH-HCC progression by reprogramming of hepatic Metabolism and microenvironment via CD36
GEO Series GSE264479. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Metabolic reprogramming and ferroptosis occurring in granulosa cells from patients with diminished ovarian reserve
GEO Series GSE286918. Homo sapiens. 116 samples. Type: Expression profiling by high throughput sequencing.
Lactyl-HDAC1-Mediated Epigenetic Gating of Angiogenic Transcription via Metabolic Reprogramming [ChIP-seq]
GEO Series GSE305252. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.