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830
datasets available to search
ShareScore release 0.9.0
Dataset results
830 results for “Tumor Microenvironment”
ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment
GEO Series GSE134388. Homo sapiens; Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma [Spatial Transcriptomics]
GEO Series GSE272236. Mus musculus. 8 samples. Type: Other.
Single Cell Analyses of Renal Cell Cancers Reveal Insights into Tumor Microenvironment, Cell of Origin, and Therapy Response
GEO Series GSE159115. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Complex I Inhibition combined with TLR Activation in the Breast Tumor Microenvironment Educates Cytotoxic Neutrophils [scRNA-seq]
GEO Series GSE272922. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Identify the role of host ATF4 on CAFs in the tumor microenvironment of large size and small size B16F10 tumors
GEO Series GSE159996. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
BRAF V600E in Pediatric Low-Grade Gliomas: Exploring the Tumor Microenvironment and Immune Cell Infiltration dynamics in vivo.
GEO Series GSE252367. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Tractable mouse TNBC models capture the heterogeneous tumor immune microenvironment and adaptation to PD-L1 blockade
GEO Series GSE292146. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment (5892)
GEO Series GSE220731. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Potent anti-tumor immunity and reversal of CD8 T cell exhaustion by spatially and functionally targeting Treg cells in the tumor microenvironment
<p>1×10<sup>6</sup> of splenic GFP<sup>+</sup> Tregs were purified from WT (n=4) and KO mice (n=4) via FACS isolation. RNA was extracted using RNeasy Micro Kit (Qiagen) following its standard protocol and RNA degradation and contamination was monitored on 1% agarose gels. For RNA sequencing, libraries were prepared using NEBNext® Ultra TM RNA Library Prep Kit for Illumina® (NEB, USA) following manufacturer’s recommendations and index codes were added to attribute sequences to each sample. The clustering of the index-coded samples was performed on a cBot Cluster Generation System using PE Cluster Kit cBot-HS (Illumina) according to the manufacturer’s instructions. After cluster generation, the library preparations were sequenced on an Illumina platform and paired-end reads were generated. All samples were prepared at the same time and sequenced on the same lane. Original image data file from high-throughput sequencing platforms (like Illumina) is transformed to sequenced reads (called Raw Data or Raw Reads) by CASAVA base recognition (Base Calling). Raw data in FASTQ format were processed through fastp. In this step, clean data (clean reads) were obtained by removing reads containing adapter and poly-N sequences and reads with low quality from raw data. All the downstream analyses were based on the clean data with high quality. Reference mouse genome and gene model annotation files were downloaded from genome website browser (NCBI/UCSC/Ensembl). Paired-end clean reads were mapped against the reference genome using the Spliced Transcripts Alignment to a Reference (STAR) software. FeatureCounts was used to count the read numbers mapped of each gene. And then RPKM (Reads Per Kilobase of exon model per Million mapped reads) of each gene was calculated based on the length of the gene and reads count mapped to this gene. The FPKM gene expression matrix, R code, DEG list, and targeted gene list are uploaded in this project.</p>
Multiplex immunohistochemistry assay to evaluate the melanoma tumor microenvironment.
<p>Representative images of triple staining. HLA expressed on the surface of the tumor cells (red arrows), nuclear expression of <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/foxp3">FOXP3</a> on Treg cells (brown arrows) and cytoplasmic expression of GRZB on <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/t-cells">T cells</a> (green arrows)</p>
Dataset of spatial transcriptomics of lung adenocarcinoma for analyzing the tumor microenvironment using topological analysis
<p>The human lung adenocarcinoma dataset for 'STopover captures spatial colocalization and interaction in the tumor microenvironment using topological analysis in spatial transcriptomics data'. </p>
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer
ClinicalTrials.gov study NCT05522907. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer
ClinicalTrials.gov study NCT05055999. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Exploring the Association of Imaging and Tumor Microenvironment in Urologic Cancer Using Radiogenomic Approach（Radiogenomics-Urinary）
ClinicalTrials.gov study NCT06537037. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
ClinicalTrials.gov study NCT05600933. IPD Sharing: YES. Countries: 1. Publications: 0.
The Gene Expression Studies of the Role of Tumor Microenvironments in Tumor Progression
ClinicalTrials.gov study NCT00638040. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy
ClinicalTrials.gov study NCT04225390. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sleep Disorders and Tumor Immune Microenvironment
ClinicalTrials.gov study NCT06941948. IPD Sharing: NO. Countries: 1. Publications: 0.
Decoding the Association of Imaging and Tumor Microenvironment in Lung Cancer Using Radiogenomic Approach（Radiogenomics-Lung）
ClinicalTrials.gov study NCT06500312. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3)
ClinicalTrials.gov study NCT04592653. IPD Sharing: UNDECIDED. Countries: 2. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.