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439
datasets available to search
ShareScore release 0.9.0
Dataset results
439 results for “early diagnosis”
Acute Lung Injury After Allogeneic Transplantation - Diagnosis and Early Treatment
ClinicalTrials.gov study NCT00852605. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Individualized Early Diagnosis and Treatment System of Gestational Diabetes Mellitus (GDM) Based on New Continuous Glucose Monitoring (CGM) Technology
ClinicalTrials.gov study NCT07276945. IPD Sharing: NO. Countries: 0. Publications: 0.
Evaluation of a Proactive Clinical Management and Early Diagnosis of Arrhythmias in Patients With Heart Failure and Non Severely Reduced Left Ventricular Function Through a Telemonitoring System
ClinicalTrials.gov study NCT05974306. IPD Sharing: NO. Countries: 0. Publications: 0.
Use of BART Coupled With EEG in the Early Diagnosis of Behavioral Disorders in Parkinson's Disease
ClinicalTrials.gov study NCT05640986. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Screening and Validation of Serum Protein Biomarkers for Early Diagnosis of Gastric Cancer
ClinicalTrials.gov study NCT07096752. IPD Sharing: NO. Countries: 0. Publications: 0.
A Biological Signature for the Early Differential Diagnosis of Psychosis
ClinicalTrials.gov study NCT06515522. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Reflective Testing for Early Diagnosis of Pituitary Dysfunction
ClinicalTrials.gov study NCT02406417. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Evaluation of Von Willebrand Factor as a Marker For Early Diagnosis of Acute Respiratory Distress Syndrome (A.R.D.S) in Comparison to Interleukin 6 [IL-6]
ClinicalTrials.gov study NCT04317469. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Role of CBC Parameters in Early Diagnosis of Pediatric Pneumonia
ClinicalTrials.gov study NCT06146400. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Health-Economic Evaluation of Early Diagnosis of Epithalial Ovarian Cancer Recurrence Using the ROMA Score: a Prospective Multicenter Randomized Trial
ClinicalTrials.gov study NCT05991752. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Neuropsychological Evaluation for Early Diagnosis of PSP
ClinicalTrials.gov study NCT03478124. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Genome-Wide DNA Methylation Profiles of Low- and High-Grade Adenoma Reveals Potential Biomarkers for Early Diagnosis of Colorectal Carcinoma
GEO Series GSE139404. Homo sapiens. 60 samples. Type: Methylation profiling by array.
Advancing diagnosis and early risk assessment of preeclampsia through non-invasive cell-free DNA methylation profiling
GEO Series GSE282512. Homo sapiens. 369 samples. Type: Methylation profiling by high throughput sequencing.
A multi biomarker panel of miRNA-lncRNA interaction; a novel approach for early diagnosis of Acute coronary syndrome
GEO Series GSE202937. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Establishment of a human tongue cancer organoid biobank enables early diagnosis, prognosis, and identification of therapeutic targets
GEO Series GSE145057. Homo sapiens. 25 samples. Type: Expression profiling by high throughput sequencing.
The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples
GEO Series GSE117063. Homo sapiens. 31 samples. Type: Expression profiling by RT-PCR.
Dataset related to article "Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer "
<p>This record contains raw data related to article “Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer"</p> <p>Abstract</p> <p><em>KRAS</em> mutations characterize pancreatic cell transformation from the earliest stages of carcinogenesis, and are present in &gt;95% of pancreatic ductal adenocarcinoma (PDAC) cases. In search of novel biomarkers for the early diagnosis of PDAC, we identified the proteins secreted by the normal human pancreatic cell line (HPDE) recently transformed by inducing the overexpression of the <em>KRAS<sup>G12V</sup></em> oncogene. We report a proteomic signature of <em>KRAS</em>-induced secreted proteins, which was confirmed in surgical tumor samples from resected PDAC patients. The putative diagnostic performance of three candidates, Laminin-C2 (LAMC2), Tenascin-C (TNC) and Pentraxin-3 (PTX3), was investigated by ELISA quantification in two cohorts of PDAC patients (<em>n</em> = 200) eligible for surgery. Circulating levels of LAMC2, TNC and PTX3 were significantly higher in PDAC patients compared to the healthy individuals (<em>p</em> &lt; 0.0001). The Receiver Operating Characteristics (ROC) curve showed good sensitivity (1) and specificity (0.63 and 0.85) for LAMC2 and PTX3, respectively, but not for TNC, and patients with high levels of LAMC2 had significantly shorter overall survival (<em>p</em> = 0.0007). High levels of LAMC2 and PTX3 were detected at early stages (I-IIB) and in CA19-9-low PDAC patients. In conclusion, pancreatic tumors release LAMC2 and PTX3, which can be quantified in the systemic circulation, and may be useful in selecting patients for further diagnostic imaging.</p>
Dataset related to article "Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer"
<p>This record contains data related to the article "Genomic instability analysis in DNA from Papanicolaou test provides proof of principle early diagnosis of high-grade serous ovarian cancer".</p><p>Abstract</p><p>Late diagnosis and the lack of screening methods for early detection define high-grade serous ovarian cancer (HGSOC) as the gynecological malignancy with the highest mortality rate. In the work presented here, we investigated a retrospective and multicentric cohort of 250 archival Papanicolaou (Pap) test smears collected during routine gynecological screening. Samples were taken at different time points (from 1 month to 13.5 years before diagnosis) from 113 presymptomatic women who were subsequently diagnosed with HGSOC (pre-HGSOC) and from 77 healthy women. Genome instability was detected through low-pass whole-genome sequencing of DNA derived from Pap test samples in terms of copy number profile abnormality (CPA). CPA values of DNA extracted from Pap test samples from pre-HGSOC women were substantially higher than those in samples from healthy women. Consistently with the longitudinal analysis of clonal pathogenic <i>TP53</i> mutations, this assay could detect HGSOC presence up to 9 years before diagnosis. This finding confirms the continual shedding of tumor cells from fimbriae toward the endocervical canal, suggesting a new path for the early diagnosis of HGSOC. We integrated the CPA score into the EVA (early ovarian cancer) test, the sensitivity of which was 75% (95% CI, 64.97 to 85.79), the specificity 96% (95% CI, 88.35 to 100.00), and the accuracy 81%. This proof-of-principle study indicates that the early diagnosis of HGSOC is feasible through the analysis of genomic alterations in DNA from endocervical smears.</p>
"Dataset related to article "Long-term sequential digital dermoscopy of low-risk patients may not improve early diagnosis of melanoma compared to pe-riodical handheld dermoscopy"
<p>This record contains data related to article "Long-term sequential digital dermoscopy of low-risk patients may not improve early diagnosis of melanoma compared to pe-riodical handheld dermoscopy" </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.