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ShareScore release 0.7.1
Dataset results
871 results for “escherichia coli”
The DNA damage response of Escherichia coli: differential gene expression after replication inhibition by azidothymidine
GEO Series GSE263906. Escherichia coli K-12. 16 samples. Type: Expression profiling by high throughput sequencing.
Redesign of an Escherichia coli Nissle treatment for phenylketonuria using insulated genomic landing pads and genetic circuits to reduce burden
GEO Series GSE228761. Escherichia coli Nissle 1917. 96 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analysis of Escherichia coli under various stress conditions
GEO Series GSE49296. Escherichia coli. 30 samples. Type: Expression profiling by genome tiling array.
Enterohemorrhagic Escherichia coli effector EspF triggers oxidative DNA lesions in intestinal epithelial cells
GEO Series GSE255129. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
RpoS acts as a global repressor of virulence gene expression in Escherichia coli O104:H4 and enteroaggregative E. coli
GEO Series GSE243699. Escherichia coli. 12 samples. Type: Expression profiling by high throughput sequencing.
A comparison between two Escherichia coli K-12 MG1655 substrains possessing different swimming motility
GEO Series GSE165438. Escherichia coli str. K-12 substr. MG1655. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional responses of Escherichia coli during recovery from inorganic or organic mercury exposure
GEO Series GSE95575. Escherichia coli str. K-12 substr. MG1655. 30 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional response induced by enteropathogenic Escherichia coli (EPEC) in mouse intestinal epithelial cells in vivo
GEO Series GSE71685. Mus musculus. 14 samples. Type: Expression profiling by array.
Cytosolic crowding drives the dynamics of both genome and cytosol in Escherichia coli challenged with sublethal antibiotic treatments
<p>Datasets used in the publication:<br> "Cytosolic crowding drives the dynamics of both genome and cytosol in Escherichia coli challenged with sublethal antibiotic treatments". <br> The archives are named according to the treatment administered and contain microscopy images of the chromosomal locus ORI2.<br> 21 fields of view were imaged for 45s at a 9.6 frame rate per second (producing 442 images) every 20 minutes for up to two hours. <br> The number after "Scan" indicates the 20 minutes intervals (1 to 6 meaning 20 to 120 minutes). The number after "Position" indicates the field of view (1 to 21). Each of these folders contains 442 images. <br> <br> Every archive also contains phase contrast images, which are in the folders containing PhC (for Phase Contrast) in the name. Each of these folders contains 21 folders (one for each position) which in turn contain 6 images, taken at the beginning of the aforementioned 45s intervals.</p> <p>Due to space limitations, we could only upload one experiment (out of 3 replicates) from only one of the 3 markers (Ori, Ter and cytoplasmic). The remaining data is available upon reasonable request from the corresponding author of the publication.<br> <br> The Excel files contain data points values and raw measurements for the plots given in Fig. 2, 6A, 6B, 6D and SI11B&C and SI12.</p> <p>The codes used to analyse the data are given at: <a href="https://github.com/ver228/bacteria-loci-tracker">https://github.com/ver228/bacteria-loci-tracker</a> </p>
Figure 1 from: Al-Rafyai HM, Alwash MS, Al-Khafaji NS (2021) Quinolone resistance (qnrA) gene in isolates of Escherichia coli collected from the Al-Hillah River in Babylon Province, Iraq. Pharmacia 68(1): 1-7. https://doi.org/10.3897/pharmacia.68.e57819
Figure 1 Geographic locations of the three sampling sites (S1–S3) along the Al Hillah River.
Data from: Modification of Escherichia coli–bacteriophage interactions by surfactants and antibiotics in vitro
Although experiments indicate that the abiotic environment plays an important role in bacterial interactions with their parasitic viruses (bacteriophages or phages), it is not yet clear how exposure to compounds present in nature alters the impact of phages on bacterial growth and evolution. To address this question, we exposed Escherichia coli K12 MG1655, in combination with three lytic phages, to various substances that natural and clinical microbial populations are likely to encounter: bile salts (present in mammalian gastrointestinal tracts), sodium dodecyl sulfate (SDS, a common surfactant in cleaning and hygiene products) and four antibiotics (present at variable concentrations in natural and clinical environments). Our results show that bile salts and SDS can reduce the detrimental effect of phages on bacterial growth. In some cases these compounds completely mitigated any negative effects of phages on bacterial growth and consequently bacteria did not evolve resistance to phages in these conditions. The proportional effects of phages were unaffected by antibiotics in most combinations, excepting three cases of phage-drug synergy. These results suggest that accounting for interactions between phages and environmental factors such as surfactants and antibiotics will improve understanding of both bacterial growth and resistance evolution to phages in vivo and in nature.
Data from: Filamentation and restoration of normal growth in Escherichia coli using a combined CRISPRi sgRNA/antisense RNA approach
CRISPR interference (CRISPRi) using dCas9-sgRNA is a powerful tool for the exploration and manipulation of gene functions. Here we quantify the reversible switching of a central process of the bacterial cell cycle by CRISPRi and an antisense RNA mechanism. Reversible induction of filamentous growth in E. coli has been recently demonstrated by controlling the expression levels of the bacterial cell division proteins FtsZ/FtsA via CRISPRi. If FtsZ falls below a critical level, cells cannot divide. However, the cells remain metabolically active and continue with DNA replication. We surmised that this makes them amenable to an inducible antisense RNA strategy to counteract FtsZ inhibition. We show that both static and inducible thresholds can adjust the characteristics of the switching process. Combining bulk data with single cell measurements, we characterize the efficiency of the switching process. Successful restoration of division is found to occur faster in the presence of antisense sgRNAs than upon simple termination of CRISPRi induction.
Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase
<p>Single-molecule data files, surface plasmon resonance data files and raw images of ensemble assays presented in "Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase". </p>
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine)
ClinicalTrials.gov study NCT02584543. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Quinolone Resistance in Bloodstream Isolates of Escherichia Coli
ClinicalTrials.gov study NCT00449735. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli
ClinicalTrials.gov study NCT02474706. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial)
ClinicalTrials.gov study NCT03365921. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Multi-Drug Resistant Organism (MDRO): Study of Highly Resistant Escherichia Coli
ClinicalTrials.gov study NCT04574596. IPD Sharing: NO. Countries: 1. Publications: 0.
Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care
ClinicalTrials.gov study NCT07236944. IPD Sharing: NO. Countries: 2. Publications: 0.
Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli
ClinicalTrials.gov study NCT02537847. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.