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460
datasets available to search
ShareScore release 0.9.0
Dataset results
460 results for “underlying mechanism”
Mechanisms Underlying Abnormal Ambulatory BP Patterns
ClinicalTrials.gov study NCT00005346. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Transcriptome sequencing to unravel the molecular mechanisms underlying the cuticle liquefaction of Antheraea pernyi following Antheraea pernyi nucleopolyhedrovirus challenge
GEO Series GSE125821. Antheraea pernyi. 6 samples. Type: Expression profiling by high throughput sequencing.
Hepatic transcriptomes reveal molecular mechanisms underlying weight divergence and growth regulation in Korean Ogye and Cornish Chickens
GEO Series GSE307722. Gallus gallus. 20 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The underlying mechanism by which SRSF1 exerted carcinogenesis and its potential targets in CRC
GEO Series GSE234580. Homo sapiens. 4 samples. Type: Other.
Comparative transcriptomic analysis reveal the regulation mechanism underlying MeJA-induced accumulation of alkaloids in Dendrobium officinale
GEO Series GSE124762. Dendrobium officinale. 6 samples. Type: Expression profiling by high throughput sequencing.
An Integrated Transcriptomic and Metabolomic Analysis of Black Spot Disease in Jinggang Honey Pomelo Reveals Underlying Resistance Mechanisms
GEO Series GSE295040. Citrus maxima. 12 samples. Type: Expression profiling by high throughput sequencing.
Elucidation of the mechanisms underlying the therapeutic effects of cell therapy using hiPSC-NPCs
GEO Series GSE276956. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Investigation of the molecular mechanisms underlying of herb pair Daji and Gancao with different combination designs acting on hepatocellular carcinoma ascites mice
GEO Series GSE76818. Mus musculus. 15 samples. Type: Expression profiling by array.
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions [H3K4me3]
GEO Series GSE261637. Homo sapiens. 49 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Single-cell RNA sequencing explores the mechanisms underlying the protective effects of myeloid cell-specific Pkm gene knockout in ALF-modeling mice
GEO Series GSE254497. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
The role of Serpinb2 and underlying mechanisms in regulating vascular inflammation during wAMD
GEO Series GSE277800. Mus musculus; Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
The underlying mechanism by which NAT10 exerted carcinogenesis and its potential targets in MM
GEO Series GSE199524. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model
GEO Series GSE197618. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Molecular mechanisms underlying heat stress effects on Mytilus edulis and galloprovincialis hybrids at early larval stages
GEO Series GSE128849. Mytilus californianus; Mytilus edulis x Mytilus galloprovincialis; Magallana gigas; Mytilus edulis; Mytilus galloprovincialis. 12 samples. Type: Expression profiling by array.
Transcriptome sequencing unveils a novel mechanism underlying breed distinctions between thin- and fat-tailed sheep
GEO Series GSE290403. Ovis aries. 18 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Neural and molecular mechanisms underlying paraventricular hypothalamus as a visceral and somatic pain sorting center
GEO Series GSE254504. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Imprinting of the Y chromosome depending on parent of origin provides insight into chromatin-modulating mechanisms underlying the Y chromosome's ability to affect gene expression diversity
GEO Series GSE42157. Drosophila melanogaster. 12 samples. Type: Expression profiling by array.
Elucidating the mechanisms underlying left ventricular function recovery in patients with ischemic heart failure undergoing surgical remodeling: A 3-dimensional ultrasound analysis.
<p>Dataset from Castelvecchio S, Frigelli M, Sturla F, Milani V, Pappalardo OA, Citarella M, Menicanti L, Votta E. Elucidating the mechanisms underlying left ventricular function recovery in patients with ischemic heart failure undergoing surgical remodeling: A 3-dimensional ultrasound analysis. J Thorac Cardiovasc Surg. 2021 Feb 26:S0022-5223(21)00381-0. doi: 10.1016/j.jtcvs.2021.02.067. Epub ahead of print. PMID: 33781593.</p> <p>Abstract </p> <p><strong>Objective: </strong>The study objective was to elucidate the mechanisms of left ventricle functional recovery in terms of endocardial contractility and synchronicity after surgical ventricular reconstruction.</p> <p><strong>Methods: </strong>Real-time 3-dimensional transthoracic echocardiography was performed on 20 patients with anterior left ventricle remodeling and ischemic heart failure before surgical ventricular reconstruction and at 6-month follow-up, and on 15 healthy controls matched by age and body surface area. Real-time 3-dimensional transthoracic echocardiography datasets were analyzed through TomTec software (4D LV-Analysis; TomTec Imaging Systems GmbH, Unterschleissheim, Germany): Left ventricle volumes, ejection fraction, and global longitudinal strain were computed; the time-dependent endocardial surface yielded by 3-dimensional speckle-tracking echocardiography was postprocessed through in-house software to quantify local systolic minimum principal strain as a measure of fiber shortening and mechanical dispersion as a measure of fiber synchronicity.</p> <p><strong>Results: </strong>Compared with controls, patients with heart failure before surgical ventricular reconstruction showed lower ejection fraction (P < .0001) and significantly impaired mechanical dispersion (P < .0001) and minimum principal strain (P < .0001); the latter worsened progressively from left ventricle base to apex. After surgical ventricular reconstruction, global longitudinal strain improved from -6.7% to -11.3% (P < .0001); mechanical dispersion decreased in every left ventricle region (P ≤ .017) and mostly in the basal region, where computed mechanical dispersion values were comparable to physiologic values (P ≥ .046); minimum principal strain improved mostly in the basal region, changing from -16.6% to -22.3% (P = .0027).</p> <p><strong>Conclusions: </strong>At 6-month follow-up, surgical ventricular reconstruction was associated with significant recovery in global left ventricle function, improved mechanical dispersion indicating a more synchronous left ventricle contraction, and improved left ventricle fiber shortening mostly in the basal region, suggesting the major role of the remote myocardium in enhancing left ventricle functional recovery.</p>
Genomic and Biological Analysis of the Mechanism Underlying Dibifree Dietary Supplement
GEO Series GSE245369. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Unraveling the underlying regulatory mechanism of the efficacy of uterine-derived decellularized extracellular matrix for endometrial regeneration and fertility enhancement
GEO Series GSE213906. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.