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897
datasets available to search
ShareScore release 0.9.0
Dataset results
897 results for “Therapeutic targets”
Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse [RNA-seq]
GEO Series GSE197417. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.
Oncogenic roles of SWI/SNF chromatin remodeling factors: therapeutic targets in T-cell acute lymphoblastic leukemia
GEO Series GSE230594. Homo sapiens. 88 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Reducing metastases stiffness by targeting fibroblasts improves therapeutic outcome in colorectal cancer [Cells]
GEO Series GSE145428. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ELAVL3 stabilizes MYCN mRNA and provides a therapeutic target in neuroendocrine prostate cancer [LNCaP/AR/shTP53/shRB1]
GEO Series GSE224909. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Integrative single-cell and spatial transcriptomic analyses identify a pathogenic cholangiocyte niche and TNFRSF12A as therapeutic target for biliary atresia
GEO Series GSE176189. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Other.
Choline Kinase Alpha (CHKα) as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma: Expression, Predictive Value, and Sensitivity to Inhibitors
GEO Series GSE112335. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Extracellular microRNA: Novel Biomarker and Potential Therapeutic Target in Trauma
GEO Series GSE223151. Homo sapiens; Mus musculus. 35 samples. Type: Non-coding RNA profiling by high throughput sequencing.
EZH2 is a potential therapeutic target for H3K27M mutant paediatric gliomas
GEO Series GSE85390. Mus musculus; Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
An inhaled therapeutic targeting a conserved RNA structure in SARS-CoV-2
GEO Series GSE174382. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells
GEO Series GSE261915. Mus musculus; Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization
GEO Series GSE298391. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Integrin-α10-dependency defines a novel therapeutic strategy targeting RAC and mTORC2 for metastatic myxofibrosarcoma
GEO Series GSE72545. Homo sapiens. 64 samples. Type: Expression profiling by array.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
GEO Series GSE193627. Mus musculus. 64 samples. Type: Expression profiling by high throughput sequencing.
Multi-Modal Comparison of human Hepatic Stellate Cells identifies novel therapeutic targets for Metabolic Dysfunction-Associated Steatotic Liver Disease
GEO Series GSE244832. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia
GEO Series GSE34941. Homo sapiens. 428 samples. Type: Expression profiling by array; Methylation profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing.
RNA m1A methyltransferase TRMT61A induces MAPK/ERK signaling and is a therapeutic target in colorectal cancer II
GEO Series GSE274028. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis
GEO Series GSE178987. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer [pSer2 Pol II ChIP-seq]
GEO Series GSE236496. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3 [RNA-Seq 2]
GEO Series GSE216053. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Identification of a Therapeutically Targetable JAK-STAT Enriched Androgen Receptor (AR) and AR Splice Variant Positive Triple Negative Breast Cancer Subtype [MDA-MB-453]
GEO Series GSE245554. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.