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514
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ShareScore release 0.9.0
Dataset results
514 results for “tumor progression”
Single-cell analysis of tumor progression reveals the function, structure, and evolution of cancer archetypes
GEO Series GSE115140. Danio rerio. 14 samples. Type: Expression profiling by high throughput sequencing.
Data set related to article "PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm"
<p>This record contains raw data related to article "PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm"</p> <p>PBX1 regulates the balance between self-renewal and differentiation of hematopoietic stem cells and maintains proto-oncogenic transcriptional pathways in early progenitors. Its increased expression was found in myeloproliferative neoplasm (MPN) patients bearing the JAK2V617F mutation. To investigate if PBX1 contributes to MPN, and to explore its potential as therapeutic target, we generated the JP mouse strain, in which the human JAK2 mutation is induced in the absence of PBX1. Typical MPN features, such as thrombocythemia and granulocytosis, did not develop without PBX1, while erythrocytosis, initially displayed by JP mice, gradually resolved over time; splenic myeloid metaplasia and in vitro cytokine independent growth were absent upon PBX1 inactivation. The aberrant transcriptome in stem/progenitor cells from the MPN model was reverted by the absence of PBX1, demonstrating that PBX1 controls part of the molecular pathways deregulated by the JAK2V617F mutation. Modulation of the PBX1-driven transcriptional program might represent a novel therapeutic approach.</p>
Vatalanib and Octreotide in Treating Patients With Progressive Neuroendocrine Tumors
ClinicalTrials.gov study NCT00227773. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Regorafenib in Subjects With Gastrointestinal Stromal Tumors (GIST) Who Have Progressed After Standard Therapy (Managed Access Program)
ClinicalTrials.gov study NCT01689376. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Regorafenib in Subjects With Gastrointestinal Stromal Tumors (GIST) Who Have Progressed After Standard Therapy
ClinicalTrials.gov study NCT01646593. IPD Sharing: Not stated. Countries: 0. Publications: 0.
DRAIC mediates hnRNPA2B1 stability and m6A-modified IGF1R instability to inhibit tumor progression [RNA-seq]
GEO Series GSE244891. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner
GEO Series GSE53778. Homo sapiens. 9 samples. Type: Expression profiling by array.
Tumor cell-specific Gpx4 deficiency reshaps tumor microenvironment and promotes NSCLC progression.
GEO Series GSE281159. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Senescence of tumor-specific Non-Classic Monocytes Facilitates Immune Suppression and Prostate Cancer Progression through Tumor and Host Immune Interactions
GEO Series GSE288749. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Nuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation [RNA-seq]
GEO Series GSE271109. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumor progression
GEO Series GSE117240. Homo sapiens. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Tumor cell-derived CTSZ mediates macrophage recruitment and M2 polarization to promote castration-resistant prostate cancer progression through the TRA2A/IL-32/ITGA5 axis
GEO Series GSE246971. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Progression of liver tumor was promoted by tris(1,3-dichloro-2-propyl)phosphate through the induction of inflammatory responses in krasV12 transgenic zebrafish
GEO Series GSE133076. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
Efficient control of tumor progression by CD4 T cell epitope-based prime-boost therapeutic vaccination
GEO Series GSE175690. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing; Other.
Stiffness-related mitochondria transfer promotes tumor progression through metabolic reprogramming
GEO Series GSE311895. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
mtROS-driven Sp1-dependent retrograde signaling promotes colorectal tumor progression via SIRT3-PAGM5 axis-governed mitochondrial homeostasis
GEO Series GSE305053. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [I]
GEO Series GSE254146. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
VGF-derived TLQP21 peptide ameliorates tumor progression, pain and depression-like behaviors in an orthotopic mouse model of pancreatic ductal adenocarcinoma
GEO Series GSE277090. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Endothelial CXCL12 regulates neovascularization during tissue repair and tumor progression
GEO Series GSE146529. Mus musculus. 192 samples. Type: Expression profiling by RT-PCR.
Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis
GEO Series GSE129106. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.