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Dataset results
637 results for “Population analysis”
Dissection of human fibroblast populations by lung regions: genomic differences and functional pathway analysis
GEO Series GSE19362. Homo sapiens. 6 samples. Type: Expression profiling by array.
Data from: Genome-wide meta-analysis of sciatica in Finnish population
Sciatica or the sciatic syndrome is a common and often disabling low back disorder in the working-age population. It has a relatively high heritability but poorly understood molecular mechanisms. The Finnish population is a genetic isolate where small founder population and bottleneck events have led to enrichment of certain rare and low frequency variants. We performed here the first genome-wide association (GWAS) and meta-analysis of sciatica. The meta-analysis was conducted across two GWAS covering 291 Finnish sciatica cases and 3671 controls genotyped and imputed at 7.7 million autosomal variants. The most promising loci (p<1x10-6) were replicated in 776 Finnish sciatica patients and 18,489 controls. We identified five intragenic variants, with relatively low frequencies, at two novel loci associated with sciatica at genome-wide significance. These included chr9:14344410:I (rs71321981) at 9p22.3 (NFIB gene; p=1.30x10-8, MAF=0.08) and four variants at 15q21.2: rs145901849, rs80035109, rs190200374 and rs117458827 (MYO5A; p=1.34x10-8, MAF=0.06; p=2.32x10-8, MAF=0.07; p=3.85x10-8, MAF=0.06; p=4.78x10-8, MAF=0.07, respectively). The most significant association in the meta-analysis, a single base insertion rs71321981 within the regulatory region of the transcription factor NFIB, replicated in an independent Finnish population sample (p=0.04). Despite identifying 15q21.2 as a promising locus, we were not able to replicate it. It was differentiated; the lead variants within 15q21.2 were more frequent in Finland (6-7%) than in other European populations (1-2%). Imputation accuracies of the three significantly associated variants (chr9:14344410:I, rs190200374, and rs80035109) were validated by genotyping. In summary, our results suggest a novel locus, 9p22.3 (NFIB), which may be involved in susceptibility to sciatica. In addition, another locus, 15q21.2, emerged as a promising one, but failed to replicate.
Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis_Spatial H&E images
<p>High-resolution H&E images of spatial transcriptome data</p>
Figure 1 in Trapping Records of Fruit Fly Pest Species (Diptera: Tephritidae) on Oahu (Hawaiian Islands): Analysis of Spatial Population Trends
Figure 1. Map of trapping sites on Oahu (2006–2008), with habitat at each site.
Figure 3 in Otolith shape analysis of three gobiid species of the Northwestern Black Sea and characterization of local populations of Neogobius melanostomus
Figure 3. – Age structure of males and females for the three species.
Figure 2 in Otolith shape analysis of three gobiid species of the Northwestern Black Sea and characterization of local populations of Neogobius melanostomus
Figure 2. – Map of the sampling stations in the Northwestern Black Sea along the Romanian coast.
Figure 5 in Otolith shape analysis of three gobiid species of the Northwestern Black Sea and characterization of local populations of Neogobius melanostomus
Figure 5. – Inter-area discrimination for Neogobius melanostomus.
A Mediation Analysis Investigating Dry Needling Treatment Mechanisms in a Chronic Low Back Pain Population
ClinicalTrials.gov study NCT06940492. IPD Sharing: NO. Countries: 1. Publications: 0.
Retrospective Analysis to Describe Patient Profiles, Current Treatment Patterns and Economic Burden for Asthma Patients in UAE. A Descriptive Analysis of the Asthma Patient Population in the Emirate o
ClinicalTrials.gov study NCT03963141. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Exploratory Analysis of Enhanced Liver Function (ELF) Test to Detect Early Fatty Liver in High Risk Population
ClinicalTrials.gov study NCT06225193. IPD Sharing: NO. Countries: 1. Publications: 0.
Genetic Analysis of Uncommon Disease Presentations in Non-US Populations
ClinicalTrials.gov study NCT06595940. IPD Sharing: NO. Countries: 1. Publications: 0.
Disease Burden Transition of Mucormycosis in Hematologic Malignancies Population Across Covid 19 Era: a Single-center Comparative Analysis From China
ClinicalTrials.gov study NCT06900114. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Survival Outcomes in Metastatic Prostate Cancer in the Brazilian Population - Analysis of Individual Characteristics and Treatment Modalities in Different National Health Institutions.
ClinicalTrials.gov study NCT04962919. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Analysis of the Pachychoroid Phenotype in an Asian Population
ClinicalTrials.gov study NCT04498000. IPD Sharing: NO. Countries: 1. Publications: 0.
Genome Analysis Across Populations in Inflammatory Bowel Disease
ClinicalTrials.gov study NCT06042387. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Analysis of the Efficiency of a Chronic Disease Self-Management Programme in a Vulnerable Population in Five European Countries
ClinicalTrials.gov study NCT03840447. IPD Sharing: NO. Countries: 1. Publications: 0.
Analysis of a Population in Extreme Age of Life With a Hip Fracture
ClinicalTrials.gov study NCT03959657. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sexual Dimorphism Analysis in Egyptian Population by Locating the Mandibular Canal Using CBCT
ClinicalTrials.gov study NCT03175445. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population
ClinicalTrials.gov study NCT00341068. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Analysis of Correlation About the Spot Urine Sodium and the Blood Pressure in General Population According to the Income Level
ClinicalTrials.gov study NCT01960608. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.