Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
13,113
datasets available to search
ShareScore release 0.9.0
Dataset results
13,113 results for “Resistivity”
Antimicrobial resistance monitoring results complementing the EU Overview Summary Report on AMR in zoonotic and indicator bacteria from humans, animals and food in 2017/2018 - Iceland
<p>This dataset contains AMR monitoring results in animals and food at the isolate level pursuant to Article 9 of Directive 2003/99/EC and to Annex, part B, of Commission implementing Decision 2013/652/EU. In addition, the dataset includes any other results from isolates than the ones mentioned in the Commission implementing Decision 2013/652/EU. The quantitative minimum inhibitory concentration (MIC) data from dilution methods are included. REPORTING AUTHORITIES CONTRIBUTING TO EACH DATA COLLECTION: AMR_2018_IS_20200204: >> Icelandic Food and Veterinary Authority</p>
Identification of candidate SNPs in the encoding region of two sugarcane cultivars as to resistance to water stress
<p>Identification of candidate SNPs in the encoding region of two sugarcane cultivars as to resistance to water stress</p>
Data from: Resistance to gapeworm parasite has both additive and dominant genetic components in house sparrows, with evolutionary consequences for ability to respond to parasite challenge
<p>Host parasite relationships are likely to change over the coming decades in response to climate change and increased anthropogenic stressors. Understanding the genetic architecture of parasite resistance will aid prediction of species' responses to intensified parasite challenge. The gapeworm "Syngamus trachea" is prevalent in natural bird populations and causes symptomatic infections ranging from mild to severe. The parasite may affect ecological processes by curtailing bird populations and is important due to its propensity to spread to commercially farmed birds. Our large scale dataset on an insular house sparrow metapopulation in northern Norway includes information on gapeworm prevalence and infection intensity, allowing assessment of the genetics of parasite resistance in a natural system. To determine whether parasite resistance has a heritable genetic component, we performed variance component analyses using animal models. Resistance to gapeworm had substantial additive genetic and dominance variance, and genome wide association studies to identify SNPs associated with gapeworm resistance yielded multiple loci linked to immune function. Together with genome partitioning results, this indicates that resistance to gapeworm is under polygenic control in the house sparrow, and likely in other bird species. Hence, our results provide the foundation needed to study any eco-evolutionary processes related to gapeworm infection, and show that it is necessary to use methods suitable for polygenic and non-additive genetic effects on the phenotype.</p>
Interspecific variation and elevated CO2 influence the relationship between plant chemical resistance and regrowth tolerance
<p>To understand how comprehensive plant defense phenotypes will respond to global change, we investigated the legacy effects of elevated CO<sub>2</sub> on the relationships between chemical resistance (constitutive and induced via mechanical damage) and regrowth tolerance in four milkweed species (<i>Asclepias</i>). We quantified potential resistance and tolerance tradeoffs at the physiological level following simulated clipping/mowing, which are relevant to milkweed ecology and conservation. We examined the legacy effects of elevated CO<sub>2 </sub>on four hypothesized tradeoffs between: 1) plant growth rate and constitutive chemical resistance (foliar cardenolide concentrations), 2) plant growth rate and mechanically induced chemical resistance, 3) constitutive resistance and regrowth tolerance, and 4) regrowth tolerance and mechanically induced resistance. We observed support for one tradeoff between plant regrowth tolerance and mechanically induced resistance traits that was, surprisingly, independent of CO<sub>2</sub> exposure. Across milkweed species, mechanically induced resistance increased by 28% in those plants previously exposed to elevated CO<sub>2. </sub> In contrast, constitutive resistance, and the diversity of mechanically induced chemical resistance traits declined in response to elevated CO<sub>2 </sub>in two out of four milkweed species. Finally, previous exposure to elevated CO<sub>2 </sub>uncoupled the positive relationship between plant growth rate and regrowth tolerance following damage. Our data highlight the complex and dynamic nature of plant defense phenotypes under environmental change and question the generality of physiologically-based defense tradeoffs.</p>
Data from: Chromosome-level genome of the melon thrips yields insights into evolution of a sap-sucking lifestyle and pesticide resistance
<p>Thrips are tiny insects from the order Thysanoptera (Hexapoda: Condylognatha), including many sap-sucking pests that are causing increasing damage to crops worldwide. In contrast to their closest relatives of Hemiptera (Hexapoda: Condylognatha) including numerous sap-sucking species, there are few genomic resources available for thrips. In this study, we assembled the first thrips genome at the chromosome level from the melon thrips, <i>Thrips palmi</i>, a notorious pest in agriculture, using PacBio long-read and Illumina short-read sequences. The assembled genome was 270.43 Mb in size with 4,120 contigs and a contig N50 of 426 kb. All contigs were assembled into 16 linkage groups assisted by the Hi-C technique. In total, 16,333 protein-coding genes were predicted, of which 88.13% were functionally annotated. Among sap-sucking insects, polyphagous species usually possess more detoxification genes than oligophagous species. The polyphagous thrips genomes characterized so far have relatively more detoxification genes in the GST and CCE families than polyphagous aphids, but they have fewer UGTs. HSP genes, especially from the Hsp70s group, have expanded in thrips compared to other hemipteran insects. These differences point to different genetic mechanisms associated with detoxification and stress responses in these two groups of sap-sucking insects. The expansion of these gene families may contribute to the rapid development of pesticide resistance in thrips, as supported by a transcriptome comparison of resistant and sensitive populations of <i>T. palmi</i>. The high-quality genome developed here provides an invaluable resource for understanding the ecology, genetics and evolution of thrips as well as their relatives more generally.</p>
Data from: The size, symmetry, and color saturation of a male guppy's ornaments forecast his resistance to parasites
Sexually selected ornaments range from highly dynamic traits to those that are fixed during development and relatively static throughout sexual maturity. Ornaments along this continuum differ in the information they provide about the qualities of potential mates, such as their parasite resistance. Dynamic ornaments enable real-time assessment of the bearer's condition: they can reflect an individual's current infection status, or resistance to recent infections. Static ornaments, however, are not affected by recent infection but may instead indicate an individual's genetically-determined resistance, even in the absence of infection. Given the typically aggregated distribution of parasites among hosts, infection is unlikely to affect the ornaments of the vast majority of individuals in a population: static ornaments may therefore be the more reliable indicators of parasite resistance. To test this hypothesis, we quantified the ornaments of male guppies, Poecilia reticulata, before experimentally infecting them with Gyrodactylus turnbulli. Males with more left-right symmetrical black coloration and those with larger areas of orange coloration, both static ornaments, were more resistant. However, males with more saturated orange coloration, a dynamic ornament, were less resistant. Female guppies often prefer symmetrical males with larger orange ornaments, suggesting parasite-mediated natural and sexual selection act in concert on these traits.
Outcomes and adverse events of pre- and extensively drug-resistant tuberculosis patients in Kinshasa, Democratique Republic of the Congo: retrospective cohort study
<p><strong>Abstract</strong></p> <p><strong>Background</strong>: Extensively drug-resistant tuberculosis (XDR TB) is a very serious form of tuberculosis that is burdened with a heavy mortality toll, especially before the advent of new TB drugs. The Democratic Republic of the Congo (DRC) is among the countries most affected by this new epidemic.</p> <p><strong>Methods:</strong> A retrospective analysis was performed of the records of all patients with pre- and extensively drug-resistant tuberculosis hospitalized from January 1, 2015 to December 31, 2017 and monitored for at least 6 months to one year after the end of their treatment in Kinshasa; an individualized therapeutic regimen with bedaquiline for 20 months was built for each patient. The adverse effects were systematically monitored.</p> <p><strong>Results:</strong> Of the 40 laboratory-confirmed patients, 32 (80%) patients started treatment, including 29 preXRB and 3 XDR TB patients. In the eligible group, 3 patients (9.4%) had HIV-TB coinfections. The therapeutic success rate was 53.2%, and the mortality rate was 46.8% (15/32); there were no relapses, failures or losses to follow-up. All coinfected HIV–TB patients died during treatment. The cumulative patient survival rate was 62.5% at 3 months, 53.1% at 6 months and 53.1% at 20 months. The most common adverse events were vomiting, Skin rash, anemia and peripheral neuropathy.</p> <p><strong>Conclusion: </strong>Bedaquiline based treatment improves patient survival in the DRC despite the still high mortality rate. The new anti-tuberculosis<br> drugs are a real hope for the management of Drug Resistant tuberculosis patient and other new therapeutic combinations may improve favorable outcomes.</p>
Data from: Antibacterial activity of graphene oxide nanosheet against multi drug resistant superbugs isolated from infected patients
Graphene oxide (GO) is a derivative of graphene nanosheet which is the most promising material of the decade in biomedical research. In particular, it has been known as an antimicrobial nanomaterial with good biocompatibility. In this study, we have synthesized and characterize GO and checked its antimicrobial property against different Gram-negative and Gram-positive multi drug resistant (MDR) hospital superbugs grown in solid agar-based nutrient plates with and without human serum through the utilization of agar well diffusion method, live/dead fluorescent staining and genotoxicity analysis. The main focus of the antimicrobial activity analysis is to distinguish the killing performance of GO in artificial and blood containing media because after injection into the bloodstream the activity of GO may be modified by adsorption of blood proteins or other biomolecules. No significant changes in antibacterial activity were found in these two different conditions. We also compare the bactericidal capability of GO with some commonly administrated antibiotics and in all cases the degree of inhibition is found to be higher. The data presented here are novel and show that GO is an effective bactericidal agents against different superbugs and can be used as a future antibacterial agent.
Data from: Evolutionary trade-offs of insecticide resistance – the fitness costs associated with target-site mutations in the nAChR of Drosophila melanogaster
<p>The evolution of resistance to drugs and pesticides poses a major threat to human health and food security. Neonicotinoids are highly effective insecticides used to control agricultural pests. They target the insect nicotinic acetylcholine receptor and mutations of the receptor that confer resistance have been slow to develop, with only one field-evolved mutation being reported to date. This is an arginine to threonine substitution at position 81 of the nAChR_β1 subunit in neonicotinoid resistant aphids. To validate the role of R81T in neonicotinoid resistance and to test whether it may confer any significant fitness costs to insects, CRISPR/Cas9 was used to introduce an analogous mutation in the genome of <i>Drosophila melanogaster</i>. Flies carrying R81T showed an increased tolerance (resistance) to neonicotinoid insecticides, accompanied by a significant reduction in fitness. In comparison, flies carrying a deletion of the whole nAChR_α<em>6</em> subunit, the target-site of spinosyns, showed an increased tolerance to this class of insecticides but presented almost no fitness deficits.</p>
Data from: Vascular epiphytes show low physiological resistance and high recovery capacity to episodic, short-term drought in Monteverde, Costa Rica
<ol> <li>Tropical montane cloud forests support abundant epiphytic vascular plant communities that serve important ecosystem functions, but their reliance on atmospheric inputs of water may make them susceptible to the drying effects of rising cloud bases and more frequent droughts.</li> <li>We conducted a common garden experiment to explore the combined effects of decreasing cloud influence—lower humidity, warmer temperature, brighter light—and meteorological drought (i.e., absence of rain) on the physiology and morphology of vascular epiphytes native to primary forests of Monteverde, Costa Rica. The epiphytes, which exhibited C<sub>3</sub> photosynthesis, were sourced from a lower montane cloud forest (CF) or a rainforest below the current cloud base (RF) and transplanted into nearby shadehouses (CF or RF shadehouse, respectively). Vapor pressure deficit (VPD) and light availability, measured as photosynthetically active radiation, were 2.5 and 3.1 times higher in the RF than the CF shadehouse. Half of the plants were subjected to a severe four-week drought followed by a recovery period, and the other half were watered controls.</li> <li>Plants subjected to low VPD/light conditions of the CF shadehouse were physiologically and morphologically resistant to the drought treatment. However, compared to control plants, both sources of plants subjected to high VPD/light conditions of the RF shadehouse experienced declines in maximum net photosynthesis (A<sub>max</sub>), stomatal conductance (g<sub>s</sub>), and the proportion of healthy leaves (those not exhibiting chlorosis, desiccation, or necrosis). At peak drought, leaves from the RF were 19% thinner than controls. Within 7-14 days after rewatering, A<sub>max</sub>, g<sub>s</sub>, and leaf health recovered to nearly the levels of controls. Growth rate, mortality, and phenology were unaffected by the treatments.</li> <li>The divergent responses to drought in the CF versus RF shadehouses, combined with the recovery in the RF shadehouse, indicate that these epiphytes possess adaptive properties that confer low resistance, but high recovery capacity, to episodes of short-term drought over a range of cloud influence. In addition, the reduction in A<sub>max</sub> suggests stomatal regulation that favors water conservation over carbon acquisition, a strategy that may inform epiphyte responses to rising clouds and increasing drought frequency expected in the long term.</li> </ol>
Species identity and diversity effects on invasion resistance of tropical freshwater plant communities
<p>Biotic resistance mediated by native plant diversity has long been hypothesized to reduce the success of invading plant species in terrestrial systems in temperate regions. However, still little is known about the mechanisms driving invasion patterns in other biomes or latitudes. We help to fill this gap by investigating how native plant community presence and diversity, and the presence of native phylogenetically closely related species to an invader, would affect invader <i>Hydrilla verticillata</i> establishment success in tropical freshwater submerged plant communities. The presence of a native community suppressed the growth of <i>H. verticillata</i>, but did not prevent its colonisation. Invader growth was negatively affected by native plant productivity, but independent of native species richness and phylogenetic relatedness to the invader. Native plant production was not related to native species richness in our study. We show that resistance in these tropical aquatic submerged plant communities is mainly driven by the presence and biomass of a native community independent of native species diversity. Our study illustrates that resistance provided by these tropical freshwater submerged plant communities to invasive species contrasts to resistance described for other ecosystems. This emphasizes the need to include understudied systems when predicting patterns of species invasiveness and ecosystem invasibility across biomes. </p>
Electrical Resistivity Tomography measurements of a limestone wall during fires
<p>The dataset comprises median reisistivity from resistivities acquiered during fires taking place in an underground limestone quarry. It comprises 24 lines, corresponding to each of the time an ERT image was acquired (the time = 0 is the time the fire was ignited); and 9 columns corresponding to each depth (median calculated on a 2-cm thick interval).</p>
Demographic analysis of invasible habitat fraction identifies context-dependent roles of resource availability and biotic resistance in determining invasion success
<p>Theories of plant invasions predict that plant communities should be more easily invaded when resources increase and/or competition decreases. We tested this with an experimentally introduced plant population by manipulating precipitation and resident community biomass. We used a spatially-explicit demographic approach to develop a new population-level metric of invasibility that quantifies the invasible habitat fraction (IHF) across the landscape.</p> <p>The existing community was essentially uninvasible (median IHF ≈ 0%), but experimental manipulations greatly increased the range of outcomes, with maximum observed IHF values over 50%. However, changes in invasibility were often context-dependent, resulting in some outcomes that aligned with existing theory, and others that were not readily predicted. Moreover, variation in invasibility was often driven by specific sets of invader demographic vital rates.</p> <p>Removing competitors revealed the capacity for strong biotic resistance, but this interacted with precipitation such that little biotic resistance was detected under drought conditions. Adding precipitation typically had little positive effect on invasibility, and moderate drought relief led to relatively high invasibility. However, the latter was driven to a large extent by interactions with mammal herbivory that otherwise inhibited invasion in one year.</p> <p><i>Synthesis</i>. Our findings show that interactions between abiotic and biotic factors, as well as legacy effects, can strongly mediate invasibility. This study also highlights the importance of incorporating spatial heterogeneity into population-level assessments of invasion, as initial population declines do not necessarily indicate resistance to invasion.</p>
Nano MOFs as targeted drug delivery agents to combat antibiotic resistant bacterial infections
<p>The drug resistance of bacteria is a significant threat to human civilization while the action of antibiotics against drug-resistant bacteria is severely limited due to the hydrophobic nature of drug molecules, which unquestionably inhibit its permanency for clinical applications. The antibacterial action of nanomaterials offers major modalities to combat drug resistance of bacteria. The current work reports, the use of nano MOFs encapsulating drug molecules to enhance its antibacterial activity against model drug-resistant free living bacteria and biofilm of the bacteria. We have attached rifampicin (RF), a well-documented antituberculosis drug with tremendous pharmacological significance, into the pore surface of zeolitic imidazolate framework 8 (ZIF8) by a <span><span>simple synthetic procedure</span></span><span>.</span> The synthesized ZIF8 has been characterized using X-ray diffraction (XRD) method before and after drug encapsulation. The electron microscopic strategies such as scanning electron microscope (SEM) and transmission electron microscope (TEM) methods was performed to characterize the binding between ZIF8 and RF. We have also performed picosecond resolved fluorescence spectroscopy to validate the formation of the ZIF8-RF nanohybrids (NHs). The drug release profile experiment demonstrates that ZIF8-RF depicts pH-responsive drug delivery and ideal for targeting bacterial disease corresponding to its inherent acidic nature. Most remarkably, ZIF8-RF gives enhanced antibacterial activity against methicillin-resistant <i>S. aureus</i> (MRSA) bacteria and also prompts entire damage of structurally robust bacterial biofilms. Overall, the present study depicts a detailed physical insight for manufactured antibiotic-encapsulated NHs presenting tremendous antimicrobial activity that can be beneficial for manifold practical applications.</p>
Diagram of apparent resistivity phase curves of magnetotelluric in Songliao Basin, Northeast China
<p>The research area is located at an expanse of 120,000 square kilometers in northeastern China, including Heilongjiang Province, Jilin Province, and Liaoning Province (about 123°-127° east longitude and about 45°-49° north latitude). The basin is divided into five primary structural units according to the distribution and development characteristics of the fault depressions, namely; the central depression zone , the southeast uplift zone , the northeast uplift zone ,the northern plunge zone , and the west slope zone . Multiple secondary fault depressions and fault uplifts lie inside. This work used a total of 157 broadband magnetotelluric sounding data points. MTU-5 magnetotelluric instruments produced by Phoenix Geophysics of Canada were used for field collection of magnetotelluric sounds and the effective frequency band was 320~0.0005 Hz. The poles were arranged according to the tensor measurement method. Each measuring point measures 5 components, 3 of them being magnetic field components while the other 2 are mutually orthogonal horizontal electric field components. The signal acquisition time was about 20 hours and the average point distance was 10 km. This is a diagram of apparent resistivity phase curves including every broadband magnetotelluric sounding data points.</p>
Adaptation by copy number variation increases insecticide resistance in the fall armyworm (vcf files)
<p>Here, I deposite vcf files used for a paper, entitled 'Adaptation by copy number variation increases insecticide resistance in the fall armyworm'.</p> <p>genotype.vcf and SNP.filtered.vcf.gz have the information of CNVs and SNPs, respectively. </p>
Evolution of morphological but not aggressiveness‐related traits following a major resistance breakdown in the poplar rust fungus, Melampsora larici‐populina
<p>Crop varieties carrying qualitative resistance to targeted pathogens lead to strong selection pressure on parasites, often resulting in resistance breakdown. It is well known that qualitative resistance breakdowns modify pathogen population structure but few studies have analysed the consequences on their quantitative aggressiveness-related traits. The aim of this study was to characterize the evolution of these traits following a resistance breakdown in the poplar rust fungus, <i>Melampsora larici-populina</i>. We based our experiment on three temporal populations sampled just before the breakdown event, immediately after and four years later. First, we quantified phenotypic differences among populations for a set of aggressiveness traits on a universally susceptible cultivar (infection efficiency, latent period, lesion size, mycelium quantity, and sporulation rate) and one morphological trait (mean spore volume). Then we estimated heritability to establish which traits could be subjected to adaptive evolution, and tested for evidence of selection. Our results revealed significant changes in the morphological trait but no variation in aggressiveness traits. By contrast, recent works have demonstrated that quantitative resistance (initially assumed more durable) could be eroded and lead to increased aggressiveness. Hence, this study is one example suggesting that the use of qualitative resistance may be revealed to be less detrimental to long term sustainable crop production.</p>
Short-term resistance that persists: Rapidly induced silicon anti-herbivore defence affects carbon-based plant defences
<p><b>1. </b>Silicon (Si) is known to alleviate diverse biotic and abiotic stresses including insect herbivory.<b> </b>Si accumulation in plants, notably the Poaceae, can be induced through stimulation of the jasmonic acid (JA) pathway (associated with chewing herbivores). Nevertheless, the temporal dynamics of Si accumulation as a defence response and its consequential effects on carbon-based defences (e.g. phenolics), particularly in the short-term, remain unclear.</p> <p><b>2. </b>The model grass <i>Brachypodium distachyon</i> was grown in a hydroponic solution where half the plants were supplemented with 2 mM potassium silicate and half had no Si supplied. Plants were treated with methyl jasmonate (MeJA) as a form of standardised simulated herbivory. We measured Si accumulation, the phytohormones JA and salicylic acid (SA), and carbon-based defences over 24 hours to determine the temporal dynamics of Si accumulation and the interplay between Si, simulated herbivory and plant defence machinery.</p> <p><b>3. </b>MeJA-induced Si accumulation occurred as early as 6 hours after treatment via increased JA concentrations. Si supplementation decreased SA concentrations, which could have implications on additional downstream defences. We show a trade-off between Si and phenolics in untreated plants, but this relationship was weakened upon MeJA treatment. Further, this trade-off did not apply to phenolic precursor compounds such as phenylalanine.</p> <p><span><b>4. </b>We provide evidence for rapidly induced Si accumulation associated with herbivory, and that increased Si accumulation impacts on phytohormones and carbon-based defences over a 24-hour period. Additionally, herbivory modifies the relationship between Si- and carbon-based defences. Thus, in addition to its well-documented role as a long-term defence against herbivores, we demonstrate that, over short-term temporal scales, Si accumulation responds to herbivore signals and impacts on plant defence machinery. </span></p>
Genomics of resistance in Norway spruce to Heterobasidion annosum s.s.and Heterobasidion parviporum
<p>Filtered variants and resistance traits to Heterobasidion annosum s.s. and Heterobasidion parviporum datasets for GWAS in Norway spruce</p>
Association between susceptibility of Thrips palmi to spinetoram and frequency of G275E mutation provides basis for molecular diagnostics of field-evolved resistance
<p><b><span>Background</span></b><span>: Spinosyn resistance is an increasing problem in field control of targeted pests. While putative mechanisms underlying spinosyn resistance have been identified in controlled studies on many species, mechanisms underlying field-evolved resistance and the development of a molecular diagnostic method for monitoring field resistance have lagged behind. Here, we examined levels of resistance of melon thrips, <i>Thrips palmi,</i> to spinetoram as well as target site mutations in field populations across China to identify potential mechanisms and useful molecular markers for diagnostic purposes.</span></p> <p><b><span>Results</span></b><span>: LC<sub>50</sub> </span><span>of 16 field-collected populations to the spinetoram varied from 0.12 to 759.34 </span>mg L<sup>-1</sup><span>. In resistant populations, we identified the G275E mutation, which has previously been linked to spinosyns resistance, as well as another nonsynonymous mutation, F314V, both located in the <i>α</i>6 subunit of the nicotinic acetylcholine receptor. There was a strong correlation between levels of spinetoram resistance and allele frequency of G275E mutation in field-collected populations (<i>r<sup>2</sup></i> = 0.84) and those reared under laboratory conditions for two to five generations (<i>r<sup>2</sup></i> = 0.91). LC<sub>50</sub> ranged from 0.12 to 0.66 </span>mg L<sup>-1</sup><span> in populations without </span><span>G275E mutation, while it ranged from </span>33.12<span> to 39.91</span> mg L<sup>-1</sup><span> in most populations with a </span><span>G275E mutation frequency > 90%, with the exception of one field-collected population which had an G275E frequency of 92% and a very high LC<sub>50</sub> value of 759.34</span> mg L<sup>-1</sup><span>, suggesting additional mechanisms.</span></p> <p><b><span>Conclusions: </span></b><span>Our results indicate that field-evolved resistance of <i>T. palmi</i> to spinetoram in China is mainly conferred by the G275E mutation, with other mechanisms contributing to a higher level of resistance. The frequency of the G275E mutation provides a useful diagnostic for quantifying resistance levels in field populations of <i>T. palmi</i>.</span></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.