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649
datasets available to search
ShareScore release 0.9.0
Dataset results
649 results for “brain gene expression”
Genome-wide temporal expression profiling of the DEGs (differentially expressed genes) in mouse stroke brain
GEO Series GSE147060. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Gene expression data from striatal regions of MPTP-intoxicated mouse brain by acupuncture
GEO Series GSE24829. Mus musculus. 8 samples. Type: Expression profiling by array.
Gene Expression data from Glioblastoma Multiforme patient tumor samples, healthy brain tissue (partly from GBM patients) and NHA cell line and Human fetal astrocyte cell line
GEO Series GSE90598. Homo sapiens. 25 samples. Type: Expression profiling by array.
Bulk tissue direct gene expression in the postmortem brains of severe acute COVID19 patients and matched controls II
GEO Series GSE274266. Homo sapiens. 12 samples. Type: Other.
Spatial transcriptomics reveals unique gene expression changes in different brain regions after sleep deprivation
GEO Series GSE222410. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Gene expression in rat brain 6 weeks after blast exposure
GEO Series GSE209992. Rattus norvegicus. 36 samples. Type: Expression profiling by high throughput sequencing.
The impact of experience-dependent and independent factors on gene expression in songbird brain [e03]
GEO Series GSE36707. Taeniopygia guttata; Haemorhous mexicanus; Loxia curvirostra. 24 samples. Type: Expression profiling by array.
Brain Gene Expression Pattern of Individuals with Dual Diagnosis who died by suicide
GEO Series GSE125681. Homo sapiens. 38 samples. Type: Expression profiling by array.
Gene expression profile of Fcrls+/CD11b+/Ly6C- microglia from the brain I
GEO Series GSE234383. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional regulation of brain gene expression in response to a territorial intrusion
GEO Series GSE32961. Gasterosteus aculeatus. 19 samples. Type: Expression profiling by array.
The impact of experience-dependent and independent factors on gene expression in songbird brain [e01]
GEO Series GSE36705. Zonotrichia leucophrys gambelii; Taeniopygia guttata. 71 samples. Type: Expression profiling by array.
Detection of differences in gene expression in the noradrenergic nuclei in the brain
GEO Series GSE138471. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling for spaceflight induced-neuroinflammation in the mouse brain
GEO Series GSE186278. Mus musculus. 12 samples. Type: Expression profiling by array.
Gene expression profiles after traumatic brain injury
GEO Series GSE24047. Rattus norvegicus. 16 samples. Type: Expression profiling by array.
Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle
GEO Series GSE11291. Mus musculus. 60 samples. Type: Expression profiling by array.
Oxytocin and Vasopressin Gene Expression in the Brain as Potential Biomarkers for Cannabidiol Exposure and Anti-inflammatory Efficacy
GEO Series GSE262437. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Expression profile of genes in normal and Down syndrome mouse brains MGU74A
GEO Series GSE1281. Mus musculus. 12 samples. Type: Expression profiling by array.
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cerebral Cortex
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight affects transcription spatially in the brain, a greater understanding of this process has the potential to aid strategies that mitigate the effects of spaceflight on the brain. Therefore, we performed GeoMx Digital Spatial Profiling of mouse brains subjected to either spaceflight or grounded controls. Four brain regions were selected: Cortex, Frontal Cortex, Corunu Ammonis I, and Dentate Gyrus. Antioxidants have emerged as a potential means of attenuating the effects of spaceflight, so we treated a subset of the mice with a superoxide dismutase mimic, MnTnBuOE-2-PyP 5+ (BuOE). Our analysis revealed hundreds of differentially expressed genes due to spaceflight in each of the four brain regions. Both common and region-specific transcriptomic responses were observed. Metabolic pathways and pathways sensitive to oxidative stress were enriched in the four brain regions due to spaceflight. These findings enhance our understanding of brain regional variation in susceptibility to spaceflight conditions. BuOE reduced the transcriptomic effects of spaceflight at a large number of genes, suggesting that this compound may attenuate oxidative stress-induced brain damage caused by the spaceflight environment. This study contains data of cerebral cortex region. The data of other brain regions are deposited in OSD-682 (cornu ammonis 1), OSD-685 (dentate gyrus), and OSD-698 (frontal cortex).
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Frontal Cortex
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight affects transcription spatially in the brain, a greater understanding of this process has the potential to aid strategies that mitigate the effects of spaceflight on the brain. Therefore, we performed GeoMx Digital Spatial Profiling of mouse brains subjected to either spaceflight or grounded controls. Four brain regions were selected: Cortex, Frontal Cortex, Corunu Ammonis I, and Dentate Gyrus. Antioxidants have emerged as a potential means of attenuating the effects of spaceflight, so we treated a subset of the mice with a superoxide dismutase mimic, MnTnBuOE-2-PyP 5+ (BuOE). Our analysis revealed hundreds of differentially expressed genes due to spaceflight in each of the four brain regions. Both common and region-specific transcriptomic responses were observed. Metabolic pathways and pathways sensitive to oxidative stress were enriched in the four brain regions due to spaceflight. These findings enhance our understanding of brain regional variation in susceptibility to spaceflight conditions. BuOE reduced the transcriptomic effects of spaceflight at a large number of genes, suggesting that this compound may attenuate oxidative stress-induced brain damage caused by the spaceflight environment. This study contains data of frontal cortex region. The data of other brain regions are deposited in OSD-682 (cornu ammonis 1), OSD-685 (dentate gyrus), and OSD-699 (cerebral cortex).
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cornu Ammonis 1
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight affects transcription spatially in the brain, a greater understanding of this process has the potential to aid strategies that mitigate the effects of spaceflight on the brain. Therefore, we performed GeoMx Digital Spatial Profiling of mouse brains subjected to either spaceflight or grounded controls. Four brain regions were selected: Cortex, Frontal Cortex, Corunu Ammonis I, and Dentate Gyrus. Antioxidants have emerged as a potential means of attenuating the effects of spaceflight, so we treated a subset of the mice with a superoxide dismutase mimic, MnTnBuOE-2-PyP 5+ (BuOE). Our analysis revealed hundreds of differentially expressed genes due to spaceflight in each of the four brain regions. Both common and region-specific transcriptomic responses were observed. Metabolic pathways and pathways sensitive to oxidative stress were enriched in the four brain regions due to spaceflight. These findings enhance our understanding of brain regional variation in susceptibility to spaceflight conditions. BuOE reduced the transcriptomic effects of spaceflight at a large number of genes, suggesting that this compound may attenuate oxidative stress-induced brain damage caused by the spaceflight environment. This study contains data of cornu ammonis 1 region. The data of other brain regions are deposited in OSD-685 (dentate gyrus), OSD-698 (frontal cortex), and OSD-699 (cerebral cortex).
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.