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Dataset results
921 results for “corticosteroid”
Corticosteroid-binding globulin (SERPINA6) consolidates sexual dimorphism of adult rat liver
GEO Series GSE245348. Rattus norvegicus. 32 samples. Type: Expression profiling by high throughput sequencing.
Data from: Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne
Urine is increasingly being considered as a source of biomarker development in Duchenne Muscular Dystrophy (DMD), a severe, life-limiting disorder that affects approximately 1 in 4500 boys. In this study, we considered the mdx mice—a murine model of DMD—to discover biomarkers of disease, as well as pharmacodynamic biomarkers responsive to prednisolone, a corticosteroid commonly used to treat DMD. Longitudinal urine samples were analyzed from male age-matched mdx and wild-type mice randomized to prednisolone or vehicle control via liquid chromatography tandem mass spectrometry. A large number of metabolites (869 out of 6,334) were found to be significantly different between mdx and wild-type mice at baseline (Bonferroni-adjusted p-value < 0.05), thus being associated with disease status. These included a metabolite with m/z = 357 and creatine, which were also reported in a previous human study looking at serum. Novel observations in this study included peaks identified as biliverdin and hypusine. These four metabolites were significantly higher at baseline in the urine of mdx mice compared to wild-type, and significantly changed their levels over time after baseline. Creatine and biliverdin levels were also different between treated and control groups, but for creatine this may have been driven by an imbalance at baseline. In conclusion, our study reports a number of biomarkers, both known and novel, which may be related to either the mechanisms of muscle injury in DMD or prednisolone treatment.
A Study of Lebrikizumab (RO5490255) in Participants With Severe Oral Corticosteroids (OCS) Dependent Asthma
ClinicalTrials.gov study NCT01987492. IPD Sharing: Not stated. Countries: 16. Publications: 0.
Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth
ClinicalTrials.gov study NCT05739682. IPD Sharing: YES. Countries: 1. Publications: 0.
CORTERAS STUDY: The Effect of Corticosteroids on Early Recovery After Major Surgery in Elderly Patients
ClinicalTrials.gov study NCT05220319. IPD Sharing: NO. Countries: 1. Publications: 0.
Assessing the Effects of a Nasal Corticosteroid on PMI-150 (Intranasal Ketamine)
ClinicalTrials.gov study NCT00662883. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ultrasound Guided Needling Versus Ultrasound Guided Corticosteroid Injection Alone, a Randomized Controlled Trial.
ClinicalTrials.gov study NCT01538758. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Rituximab Plus Corticosteroids in Non-infectious Active Mixed Cryoglobulinemia Vasculitis
ClinicalTrials.gov study NCT02556866. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids
ClinicalTrials.gov study NCT01388764. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Nomacopan Therapy in Adult Patients With Bullous Pemphigoid Receiving Adjunct Oral Corticosteroid Therapy (ARREST-BP)
ClinicalTrials.gov study NCT05061771. IPD Sharing: NO. Countries: 4. Publications: 0.
A Single-dose, Randomised, Crossover, Placebo-controlled Study Assessing Two Fixed-dose Combinations of Inhaled Long-acting Beta-agonist and Corticosteroid
ClinicalTrials.gov study NCT02094274. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty
ClinicalTrials.gov study NCT03445611. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Low Dose Antenatal Corticosteroids for Late Preterm Delivery
ClinicalTrials.gov study NCT05698966. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Study Comparing Viscosupplementation and Corticosteroid Injections for Knee Osteoarthritis
ClinicalTrials.gov study NCT01132677. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficacy of Ultrasound-Guided PRP Versus Corticosteroid Injection in Patients With Ulnar Neuropathy at Elbow
ClinicalTrials.gov study NCT05567081. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
The Influence of Corticosteroid Treatment on Heart Function
ClinicalTrials.gov study NCT02232048. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Inhaled Corticosteroid Replacement Study - Efficacy and Safety of Ro 27-2441 (Test Drug) in Moderate Persistent Asthma
ClinicalTrials.gov study NCT00048022. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Comparison of Two Different Methods of Delivering Local Analgesia During Intra-articular Corticosteroid Injections in Children With Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT00465504. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Oral Zinc Supplementation as an Adjuvant to Topical Corticosteroid in Oral Lichen Planus Patients
ClinicalTrials.gov study NCT04278599. IPD Sharing: Not stated. Countries: 1. Publications: 0.
To Assess the Pharmacokinetics, Safety and Tolerability of Abediterol Administered Once Daily for 9 Days, in Patients With Asthma on Inhaled Corticosteroids
ClinicalTrials.gov study NCT03273127. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.