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10,694 results for “carcinoma,”
Systematic analysis identifies CDKN2A as a prognostic biomarker for hepatocellular carcinoma
Open the record for dataset details and reuse information.
data - ERα Inhibits the Progression of Hepatocellular Carcinoma by Regulating the CircRNA/miRNA/SMADs Network
Open the record for dataset details and reuse information.
Raw IMC files for Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data.
<p>Raw MCD files for the Stanford cohort of oral squamous cell carcinoma patients in this publication:</p> <p>Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data (DOI:<span> <a href="https://doi.org/10.1016/j.isci.2023.108486" target="_blank" rel="noopener">10.1016/j.isci.2023.108486</a>).</span></p>
Ovarian carcinoma (OV)
<p>Ovarian carcinoma data from TCGA.</p>
Clinical and histopathological features of 81 cases of canine apocrine gland carcinoma of the anal sac
<p>Canine apocrine gland anal sac adenocarcinoma (AGASAC) is a malignant tumour with variable clinical progression. The objective of this study was to use robust multivariate models, based on models employed in human medical oncology, to establish clinical and histopathological risk factors of poor survival. Clinical data and imaging of 81 cases with AGASAC were reviewed. Tissue was available for histological review and immunohistochemistry in 49 cases. Tumour and lymph node size were determined using the response evaluation criteria in solid tumours system (RECIST). Modelling revealed tumour size over 2 cm, lymph node size grouped in three tiers by the two thresholds 1.6 cm and 5 cm, surgical management, and radiotherapy were independent clinical variables associated with survival, irrespective of tumour stage. Tumour size over 1.3 cm and presence of distant metastasis were independent clinical variables associated with first progression free interval. The presence of the histopathological variables of tumour necrosis, a solid histological pattern, and vascular invasion in the primary tumour were independent risk factors of poor survival. Based upon these independent risk factors, scoring algorithms to predict survival in AGASAC patients are presented.</p>
Raw data of manuscript "Downregulated dual-specificity protein phosphatase 1 in ovarian carcinoma: a comprehensive study with multiple methods" submitted to PeerJ
<p>Some raw data and original calculating results of this manuscript.</p>
Downregulation of ST6GAL1 promotes liver inflammation and predicts adverse prognosis in hepatocellular carcinoma
<p>Original file of <em>Downregulation of ST6GAL1 promotes liver inflammation and predicts adverse prognosis in hepatocellular carcinoma.</em></p>
CTLA-4 and PD-1 expressed in EMT6 mouse mammary carcinoma cell line acquired radio-resistance to gamma-ray irradiation.
<p>Supplementary File of manuscript entitled CTLA-4 and PD-1 expressed in EMT6 mouse mammary carcinoma cell line acquired radio-resistance to gamma-ray irradiation.</p>
Radiomics metrics combined with clinical data in the surgical management of early-stage (cT1-T2 N0) of tongue squamous cell carcinomas: a preliminary study
<p>We uploaded the clinical and the hematological parameters of enrolled patients in the study "Radiomics metrics combined with clinical data in the surgical management of early-stage (cT1-T2 N0) of tongue squamous cell carcinomas: a preliminary study" accepted on Biology journal.</p> <p>Clinical and hematological parameters include: age; gender; DOI, NLR; PLR; LMR; SIRI; SII; T stage; grading; metastatic lymph nodes; perineural infiltration; vascular infiltration.</p> <p> </p>
Network Pharmacology-based Approach combined with Bioinformatic Analytics to Elucidate the Potential of Curcumol Against Hepatocellular Carcinoma
<p>File S1: Expression distribution of common targets; File S2: GSEA result of common targets, File S3: Rare data for top 10 most enriched GO terms in biological process, cellular component, and molecular function of common targets, File S4: Rare data for KEGG enrichment result of common targets, File S5: Rare data for cluster classification performed by MCODE, File S6: Rare data for GO terms and KEGG pathways enrichment analyses of cluster 1 and cluster 2, File S7: Prognosis-related genes, Table S1: Putative targets of curcumol.</p>
Downregulation of ST6GAL1 promotes liver inflammation and predicts adverse prognosis in hepatocellular carcinoma
<p>Original file of <em>Downregulation of ST6GAL1 promotes liver inflammation and predicts adverse prognosis in hepatocellular carcinoma.</em></p>
CLIC1 plasma concentration is associated with lymph node metastases in oral squamous cell carcinoma - Supplementary Material (Statistical Analysis)
<p>Supplementary file containing detailed statistical analysis of results of the article <em>CLIC1 plasma concentration is associated with lymph node metastases in oral squamous cell carcinoma.</em></p>
A Riskscore Model for Predicting Survival, Tumor Microenvironment, Immunotherapy and drug sensitivity of Lung Squamous Cell Carcinoma Based on PI3K/AKT/MTOR Pathway-Related Genes
<p>Firstly, the data we provide is the raw data downloaded from the TCGA database. Secondly, we provide the following explanations for the raw data, taking Figure 1 as an example:</p> <p>First, we selected a LUSC dataset from the TCGA database that includes RNA-seq data (FPKM values) and clear clinical information, consisting of 51 normal samples and 501 LUSC samples. The raw data <span>can be found in</span> the "mRNA" document in the "Fig.1" file<span>, and t</span>he data includes TCGA <span>id</span> information.</p> <p>Next, the data was imported into "mRNA_edgeR" to analyze whether the RNA-seq data from these 552 samples meet the criteria of |logFC| > 0.585 and FDR < 0.05, <span>and the results are shown in</span> the "diffSig" table. Subsequently, the genes in the "diffSig" table were intersected with 105 PAGs, <span>and</span> 44 key PAGs <span>were identified, </span>as shown in Figure 1.</p> <p>The <span>other</span> figures can <span>also </span>be reproduced sequentially based on the methods described <span>above</span>.</p> <p>Furthermore, due to the limited number of LUSC patients, the clinical information in the database is relatively incomplete. Hence, the clinical information that we provide constitutes the entire content available in the database.</p>
Validation and Test Datasets for "High-resolution AI image dataset for diagnosing oral submucous fibrosis and squamous cell carcinoma"
<p>This deposition contains the validation and test dataset for our study "High-resolution AI image dataset for diagnosing oral submucous fibrosis and squamous cell carcinoma".</p> <p>The training dataset for this study can be found at the following DOI: [<strong>10.5281/zenodo.12636426</strong>].<br><br></p>
Genetic alterations and expression programs of oral squamous cell carcinoma associated with betel quid chewing
<p><span>Betel quid (BQ) chewing is a profound risk for</span><span> oral squamous cell carcinoma (OSCC) <span>in Southeast Asia.</span> To decipher contributory genomic abnormalities and transcriptional reprogramming in these malignancies, we conducted a multi-omics survey, including exome sequencing of tumor-normal pairs from <span>261 male </span>patients with OSCC (129 habitual BQ chewers and 132 non-BQ users), alone with integrated single-cell and spatial transcriptomics of a set of tumors. Comparative analyses of the mutational catalog identified enrichment of significantly altered genes (e.g mutations of <em>TP53</em> and <em>CHUK</em>, copy gains of <em>MAP3K13</em> and <em>FADD</em>, copy losses of <em>CDKN2A</em>) and mutational signatures associated with BQ chewing. Assessment of oncogenic and co-occurring actionable alterations demonstrated frequently altered oncogenic pathways (Hippo and p53 signaling) and potential combination therapy opportunities linked to BQ use. In addition, evaluation of epithelial, immune, stromal expression programs in the corresponding tissue compartments revealed a shift of tumor microenvironment in BQ-related OSCC, characterized by induced hypoxia of tumor epithelium, altered immunosuppression of dendritic cells, and raised sprouting angiogenesis of tumor endothelium. Quantitative predictions of intercellular communications inferred a more heterogeneous cell-cell crosstalk among BQ-related OSCC, highlighted by extensive interactions of fibroblasts and dendritic cells with other non-epithelial cell types via mostly extracellular matrix-receptor signaling pathways. Collectively, these differences in genomic landscape and tumor niche suggest that OSCC caused by BQ chewing could be an etiological subtype different from their BQ-negative counterparts.</span></p>
The supplementary materials of "Molecular Analysis of High-grade Serous Ovarian Carcinoma Exhibiting Low-grade Serous Carcinoma and Serous Borderline Tumor"
<p>This is supplementary materials of an article named </p> <p><span>Molecular Analysis of High-grade Serous Ovarian Carcinoma Exhibiting Low-grade Serous Carcinoma and Serous Borderline Tumor.</span></p>
Supplemental Material from: Immune Profiling of Thyroid Carcinomas Suggests the Existence of Two Major Phenotypes with Different Treatment Needs
<p>Supplemental data from: <strong>Immune Profiling of Thyroid Carcinomas Suggests the Existence of Two Major Phenotypes with Different Treatment Needs</strong></p>
Immune Profiling of Thyroid Carcinomas Suggests the Existence of Two Major Phenotypes with Different Treatment Needs: Supplemental Material
<p>Supplemental Material from: Immune Profiling of Thyroid Carcinomas Suggests the Existence of Two Major Phenotypes with Different Treatment Needs</p>
Supplemental Material from: Immune Profiling of Thyroid Carcinomas Suggests the Existence of Two Major Phenotypes with Different Treatment Needs
<p>Supplemental Data from "Immune Profiling of Thyroid Carcinomas Suggests the Existence of Two Major Phenotypes with Different Treatment Needs"</p>
dataset for paper: Sodium Levels and Outcomes in Patients With Metastatic Renal Cell Carcinoma Receiving Nivolumab
<p>dataset for paper: Sodium Levels and Outcomes in Patients With Metastatic Renal Cell Carcinoma Receiving Nivolumab</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.