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665
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ShareScore release 0.9.0
Dataset results
665 results for “whole blood”
Protein-coding and non-coding RNA expression in whole blood leukocytes during experimental human endotoxemia.
GEO Series GSE134356. Homo sapiens. 36 samples. Type: Expression profiling by array.
Expression data from peripheral whole blood of non-IBD controls, CD and UC patients
GEO Series GSE94648. Homo sapiens. 97 samples. Type: Expression profiling by array.
Whole blood transcriptomic profiling in men and women with heart failure
GEO Series GSE181114. Homo sapiens. 944 samples. Type: Expression profiling by array.
Whole blood transcriptome profile identifies motor neurone disease (MND) RNA biomarker signatures
GEO Series GSE277709. Homo sapiens. 84 samples. Type: Expression profiling by high throughput sequencing.
Whole blood transcriptomics characterize molecular phenotypes of pulmonary Mycobacterium avium complex disease
GEO Series GSE288604. Homo sapiens. 200 samples. Type: Expression profiling by high throughput sequencing.
Gene expression data from whole blood of a Phase II randomized clinical trial of the treatment of methamphetamine dependence with topiramate
GEO Series GSE107015. Homo sapiens. 209 samples. Type: Expression profiling by array.
Whole blood gene expression of rheumatoid arthritis
GEO Series GSE93272. Homo sapiens. 275 samples. Type: Expression profiling by array.
Global gene expression profiles in whole blood total RNA from patients with lupus nephritis, before and after initiation of therapy
GEO Series GSE72747. Homo sapiens. 30 samples. Type: Expression profiling by array.
Expression data from whole blood sample of eight kinds of TCM syndromes of rheumatoid arthritis patients.
GEO Series GSE205962. Homo sapiens. 20 samples. Type: Expression profiling by array.
Transcriptional analysis of whole blood, primary fibroblasts, and PBMCs upon TNF-alpha or IL-1beta stimulation from HOIL-1-deficient patients
GEO Series GSE40752. Homo sapiens. 150 samples. Type: Expression profiling by array.
Dataset related to the article "Whole-blood transcriptome unveils altered immune response in acute myocardial infarction patients with aortic valve sclerosis"
<p>This record contains raw data related to the article "Whole-blood transcriptome unveils altered immune response in acute myocardial infarction patients with aortic valve sclerosis"</p><p><strong>Abstract</strong></p><p><strong>Background: </strong>Aortic valve sclerosis (AVSc) presents similar pathogenetic mechanisms to coronary artery disease (CAD) and is associated with short- and long-term mortality in CAD patients. Evidence of AVSc-specific pathophysiological traits in acute myocardial infarction (AMI) is currently lacking. Thus, we aimed to identify a blood-based transcriptional signature that could differentiate AVSc from non-AVSc patients during AMI.</p><p><strong>Methods: </strong>Whole-blood transcriptome of AVSc (n = 44) and no-AVSc (n = 66) patients with AMI was assessed by RNA-sequencing on hospital admission. Feature selection, differential expression, and enrichment analyses were performed to identify gene expression patterns discriminating AVSc from no-AVSc and infer functional associations. Multivariable Cox regression analysis was used to estimate the hazard ratios of cardiovascular events in AVSc versus no-AVSc patients.</p><p><strong>Results:</strong> This cross-sectional study identified a panel of 100 informative genes capable of distinguishing AVSc from no-AVSc patients with 94% accuracy. Further analysis revealed significant mean differences in 143 genes, of which 30 genes withstood correction for age and previous AMI or coronary interventions. Functional inference unveiled a significant association between AVSc and key biological processes, including acute inflammatory responses, type I interferons (IFN) response, platelet activation, and hemostasis. Notably, AMI patients with AVSc exhibited a significantly higher incidence of adverse cardiovascular events during a 10-year follow-up period, with a full adjusted hazard ratio of 2.4 (95% CI 1.3–4.5).</p><p><strong>Conclusions:</strong> Our findings shed light on the molecular mechanisms underlying AVSc and provide potential prognostic insights for AMI patients with AVSc. During AMI, AVSc patients showed increased type I IFN response and earlier adverse cardiovascular outcomes. Novel pharmacological therapies aiming at limiting type I IFN response during or immediately after AMI might improve poor cardiovascular outcomes of AMI patients with AVSc.</p><p><strong>Keywords:</strong></p><p> Aortic valve sclerosis; acute myocardial infarction; immune response; inflammation; cardiovascular adverse events; risk stratification.</p>
INTERCEPT Safety Evaluation on Whole Blood
ClinicalTrials.gov study NCT04020224. IPD Sharing: NO. Countries: 0. Publications: 0.
Collection of Human Liver Biopsy and Whole Blood Samples From T1DM, TP or PP Patients for Potential Use for Insulin Producing Cells in Future Clinical Studies
ClinicalTrials.gov study NCT04038931. IPD Sharing: Not stated. Countries: 0. Publications: 0.
An Exploratory Clinical Trial to Generate Whole Blood Samples for Analysing Genetic Polymorphisms
ClinicalTrials.gov study NCT02057497. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Variability of Whole Blood Clotting Time Measurements in Ex Vivo Human Blood Samples Spiked With Anticoagulants
ClinicalTrials.gov study NCT03296982. IPD Sharing: Not stated. Countries: 0. Publications: 0.
The Association Between the Intraoperative Blood Pressure Changes and Whole Exome Genome
ClinicalTrials.gov study NCT05730140. IPD Sharing: NO. Countries: 0. Publications: 0.
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for CABG Surgery
ClinicalTrials.gov study NCT02757027. IPD Sharing: NO. Countries: 0. Publications: 0.
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for Colon Surgery
ClinicalTrials.gov study NCT02770027. IPD Sharing: NO. Countries: 0. Publications: 0.
Evaluation of Viatar™ Oncopheresis System in Removing CTC From Whole Blood
ClinicalTrials.gov study NCT03058809. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for Cardiac Surgery
ClinicalTrials.gov study NCT02757118. IPD Sharing: NO. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.