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897 results for “Therapeutic targets”

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geo20/100

Genomic and expression profiling identifies Syk as a possible therapeutic target in mantle cell lymphoma

GEO Series GSE4176. Homo sapiens. 36 samples. Type: Expression profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array.

openGEO-OpenFeb 2006View details →
geo20/100

Identification of a Therapeutically Targetable JAK-STAT Enriched Androgen Receptor (AR) and AR Splice Variant Positive Triple Negative Breast Cancer Subtype

GEO Series GSE244283. Homo sapiens. 58 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo20/100

Targeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma [ChIPseq_IMR5_RNAseqH1]

GEO Series GSE152477. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2020View details →
geo20/100

Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signalling identifies therapeutic targets for Colorectal Cancer (ChIP-seq)

GEO Series GSE156081. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2021View details →
geo20/100

Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer

GEO Series GSE191106. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo20/100

Identification of Unique Therapeutic Targets in Esophageal Squamous Cell Carcinoma

GEO Series GSE29001. Homo sapiens. 45 samples. Type: Expression profiling by array.

openGEO-OpenMay 2011View details →
geo20/100

PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination [exvivo]

GEO Series GSE280578. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo20/100

Identification of fibroblast-derived sFRP2 as a new therapeutic target and engineering of siRNA therapies for uterine scarring

GEO Series GSE293910. Mus musculus; Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo20/100

RNA aptamers specific for transmembrane p24 trafficking protein 6 and Clusterin for the targeted delivery of imaging reagents and RNA therapeutic to human β cells

GEO Series GSE162273. Homo sapiens. 4 samples. Type: Protein profiling by protein array.

openGEO-OpenFeb 2022View details →
geo20/100

Cell Cycle-Targeting MicroRNAs as Therapeutic Tools Against Refractory Cancers [SW900 cells]

GEO Series GSE77229. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2017View details →
geo20/100

Targeting IRAK1 as a therapeutic approach for Myelodysplastic Syndrome

GEO Series GSE46346. Homo sapiens. 8 samples. Type: Expression profiling by array.

openGEO-OpenApr 2013View details →
geo20/100

Phase separation of RXRγ drives tumor chemoresistance and represents a therapeutic target for small cell lung cancer [ChIP-Seq]

GEO Series GSE268220. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2024View details →
geo20/100

The histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target in BRAF/MEK inhibitor-resistant melanoma

GEO Series GSE109678. Homo sapiens. 13 samples. Type: Expression profiling by array.

openGEO-OpenDec 2019View details →
geo20/100

The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age [methylatio

GEO Series GSE280472. Mus musculus; Rattus; Macaca mulatta; Homo sapiens. 36 samples. Type: Methylation profiling by genome tiling array.

openGEO-OpenMar 2025View details →
geo20/100

Mitochondrial SHMT2 is a crucial therapeutic target in dedifferentiated thyroid cancer (2nd study)

GEO Series GSE223765. Homo sapiens. 65 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2024View details →
geo20/100

PAK1 is a Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome

GEO Series GSE70791. Homo sapiens. 8 samples. Type: Expression profiling by array.

openGEO-OpenJul 2015View details →
geo20/100

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets (mRNA)

GEO Series GSE59701. Homo sapiens. 24 samples. Type: Expression profiling by array.

openGEO-OpenMar 2015View details →
geo20/100

14-kDa Phosphohistidine Phosphatase is a Potential Therapeutic Target for Liver Fibrosis

GEO Series GSE157814. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2021View details →
geo20/100

DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma [ChIP-seq]

GEO Series GSE209811. Mus musculus. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo20/100

Targeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma [ChIPseq_IMR5]

GEO Series GSE152476. Homo sapiens. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2020View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record