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5,805
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5,805 results for “Data model”
Study of Huntington disease by analyzing RNA-Seq data using fly and mouse models
GEO Series GSE32192. Mus musculus; Drosophila melanogaster. 7 samples. Type: Expression profiling by high throughput sequencing.
Expression data for mouse skin-in atopy DNCB model
GEO Series GSE195596. Mus musculus. 8 samples. Type: Expression profiling by array.
Expression data for cultured NCI-H1299 parental and spheroid cells as well as their derived xenograft models
GEO Series GSE21612. Homo sapiens. 12 samples. Type: Expression profiling by array.
Expression data from sorafenib-resistant HCC cells, xenograft model and the corresponding counterparts.
GEO Series GSE121153. Homo sapiens. 10 samples. Type: Expression profiling by array.
Expression data of murine model of cardiac hypertrophy
GEO Series GSE26671. Mus musculus. 12 samples. Type: Expression profiling by array.
In vitro to in vivo extrapolation modeling to facilitate the integration of transcriptomics data into genotoxicity assessment
GEO Series GSE281641. Homo sapiens. 161 samples. Type: Expression profiling by high throughput sequencing; Other.
Gene expression data from the syngeneic mouse endometriosis model
GEO Series GSE190209. Mus musculus. 15 samples. Type: Expression profiling by array.
mRNA Expression data from murine hearts subjected to ligation of the left anterior descending coronary artery (myocardial infarction, MI model) or sham surgery (SH)
GEO Series GSE71906. Mus musculus. 12 samples. Type: Expression profiling by array.
Expression data from HoxA9wt/Meis1 vs. HoxA9AA/Meis1 mouse models
GEO Series GSE288783. Mus musculus. 6 samples. Type: Expression profiling by array.
Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma
DNA and RNA were isolated from snap frozen primary tumor tissue (human and mouse), and DNA was isolated from matched normal tissue (region matched non-tumor tissue for human, tail section for mouse). A mouse leg was also injected with cardiotoxin to induce tissue damage was taken following sacrifice and was snap frozen, then processed for RNA isolation to serve as a mouse tissue-normal for RNA sequencing. All sequencing was performed at the OHSU MPSSR core.
Balmorel input data for comparative modelling of CSP + TES and PVS
<p><strong>Description of the dataset</strong></p> <p>This dataset holds all Balmorel model input data as well as the Balmorel code used for the scenarios of the paper 'Making the sun shine at night: Comparing Concentrating Solar Power and Photovoltaics with battery storage' submitted to 'Energy Sources, Part B: Economics, Planning, and Policy.'</p> <p><strong>Data format</strong></p> <p>We provide the data in form of the data folders holding the .inc files for all scenarios as well as the Balmorel model folder containing the GAMS code.</p> <p>The original Balmorel source code is available under https://github.com/balmorelcommunity/Balmorel under the ISC license. It was adapted in order to include a new technology generating electricity from heat (GETOH). The inputs for this development were kindly supported by DTU and Ea Energy Analyses with previously done works</p> <p> </p>
Input data for a spatial urban sprawl model
<p>Input data for projecting global urban extent under future shared socioeconomic pathways (2010-2100)</p>
Matlab Codes for the data-driven model
<p>Main function: f_data_driven_model</p> <p>For detail of the methodology, please see the paper entitled "A machine-learning-based modeling for water quality in coastal waters- taking dissolved oxygen and hypoxia in Chesapeake Bay as an example" by Yu et al. </p> <p>This is the first version. </p>
Supporting data case study, ensemble climate-impact modelling
<p>Data supporting the case study in 'Ensemble climate-impact modelling: extreme impacts from moderate meteorological conditions', publication under review.</p>
data set from Mollica G, Senesi P, Codella R, Vacante F, Montesano A, Luzi L, Terruzzi I. L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. Dig Liver Dis. 2020 Mar;52(3):314-323. doi: 10.1016/j.dld.2019.09.002. Epub 2019 Oct 10. PMID: 31607566.
<p>data set from Mollica G, Senesi P, Codella R, Vacante F, Montesano A, Luzi L, Terruzzi I. L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. Dig Liver Dis. 2020 Mar;52(3):314-323. doi: 10.1016/j.dld.2019.09.002. Epub 2019 Oct 10. PMID: 31607566.</p> <p> </p> <p>This is the abstract:</p> <p>Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disorder. NAFLD, associated lipotoxicity, fibrosis, oxidative stress, and altered mitochondrial metabolism, is responsible for systemic inflammation, which contributes to organ dysfunction in extrahepatic tissues, including the heart. We investigated the ability of L-carnitine (LC) to oppose the pathogenic mechanisms underlying NAFLD progression and associated heart dysfunction, in a mouse model of methionine-choline-deficient diet (MCDD). Mice were divided into three groups: namely, the control group (CONTR) fed with a regular diet and two groups fed with MCDD for 6 weeks. In the last 3 weeks, one of the MCDD groups received LC (200 mg/kg each day) through drinking water (MCDD + LC). The hepatic lipid accumulation and oxidative stress decreased after LC supplementation, which also reduced hepatic fibrosis via modulation of α-smooth muscle actin (αSMA), peroxisome-activated receptor gamma (PPARγ), and nuclear factor kappa B (NfƙB) expression. LC ameliorated systemic inflammation, mitigated cardiac reactive oxygen species (ROS) production, and prevented fibrosis progression by acting on signal transducer and activator of transcription 3 (STAT3), extracellular signal-regulated kinase 1-2 (ERK1-2), and αSMA. This study confirms the existence of a relationship between fatty liver disease and cardiac abnormalities and highlights the role of LC in controlling liver oxidative stress, steatosis, fibrosis, and NAFLD-associated cardiac dysfunction.</p> <p> </p>
Data set and 3d model from Emendi M, Sturla F, Ghosh RP, Bianchi M, Piatti F, Pluchinotta FR, Giese D, Lombardi M, Redaelli A, Bluestein D. Patient-Specific Bicuspid Aortic Valve Biomechanics: A Magnetic Resonance Imaging Integrated Fluid-Structure Interaction Approach. Ann Biomed Eng. 2020 Aug 17. doi: 10.1007/s10439-020-02571-4. Epub ahead of print. PMID: 32804291.
<p>Data set and 3d model from Emendi M, Sturla F, Ghosh RP, Bianchi M, Piatti F, Pluchinotta FR, Giese D, Lombardi M, Redaelli A, Bluestein D. Patient-Specific Bicuspid Aortic Valve Biomechanics: A Magnetic Resonance Imaging Integrated Fluid-Structure Interaction Approach. Ann Biomed Eng. 2020 Aug 17. doi: 10.1007/s10439-020-02571-4. Epub ahead of print. PMID: 32804291.</p> <p> </p> <p>This is the abstract:</p> <p>Congenital bicuspid aortic valve (BAV) consists of two fused cusps and represents a major risk factor for calcific valvular stenosis. Herein, a fully coupled fluid-structure interaction (FSI) BAV model was developed from patient-specific magnetic resonance imaging (MRI) and compared against in vivo 4-dimensional flow MRI (4D Flow). FSI simulation compared well with 4D Flow, confirming direction and magnitude of the flow jet impinging onto the aortic wall as well as location and extension of secondary flows and vortices developing at systole: the systolic flow jet originating from an elliptical 1.6 cm<sup>2</sup> orifice reached a peak velocity of 252.2 cm/s, 0.6% lower than 4D Flow, progressively impinging on the ascending aorta convexity. The FSI model predicted a peak flow rate of 22.4 L/min, 6.7% higher than 4D Flow, and provided BAV leaflets mechanical and flow-induced shear stresses, not directly attainable from MRI. At systole, the ventricular side of the non-fused leaflet revealed the highest wall shear stress (WSS) average magnitude, up to 14.6 Pa along the free margin, with WSS progressively decreasing towards the belly. During diastole, the aortic side of the fused leaflet exhibited the highest diastolic maximum principal stress, up to 322 kPa within the attachment region. Systematic comparison with ground-truth non-invasive MRI can improve the computational model ability to reproduce native BAV hemodynamics and biomechanical response more realistically, and shed light on their role in BAV patients' risk for developing complications; this approach may further contribute to the validation of advanced FSI simulations designed to assess BAV biomechanics.</p> <p> </p>
Model output data for Fujimori et al., Impacts of GHG emissions abatement measures on agricultural market and food security
<p>Model output data for "Fujimori et al., Impacts of GHG emissions abatement measures on agricultural market and food security" submitted to Nature Food</p>
Data of resulting velocity and anisotropic models, and travel-times of the Tanlu fault zone
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Data for Development of a lifetime model for large format nickel-manganese-cobalt oxide-based lithium-ion cell validated using a real-life profile
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Data for "Impact of Relaxation Time on Electrochemical Impedance Spectroscopy Characterization of the Most Common Lithium Battery Technologies—Experimental Study and Chemistry-Neutral Modeling"
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ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.