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5,826 results for “Randomized trial”
Dataset for "Informed Consent to Study Purpose in Randomized Clinical Trials of Antibiotics, 1991 Through 2011"
<p>This dataset includes all of the underlying data for our study, published in JAMA Internal Medicine (<em>JAMA Intern Med.</em> 2017;177(10):1452-1459. doi:10.1001/jamainternmed.2017.3820), along with our extraction sheets and work files.</p>
Variations of HRV and skin conductance reveal the influence of CV4 and Rib Raising techniques on autonomic balance: A randomized controlled clinical trial
<p>Variations of HRV and skin conductance reveal the influence of CV4 and Rib Raising techniques on autonomic balance: A randomized controlled clinical trial</p> <p> </p> <p>Introduction: The aim of the present study was to evaluate whether Fourth Ventricle Compression</p> <p>Technique (CV4) and Rib Raising (RR) osteopathic techniques influence Autonomic Nervous System (ANS) activity, as measured by Heart Rate Variability (HRV) and Skin Conductance (SC).</p> <p>Method: A randomized-controlled clinical trial has been performed from June 2010 to January 2011. 32 healthy adults (33.9 ± 14 years, and 72% female) were selected. Subjects were randomized in three groups: CV4 group, RR group and Placebo group. Each subject of each group underwent respective technique only once. HRV and SC were continuously recorded during the session. All data analysis was performed using SPSS statistical software (version 21.0) and the significance level was considered at p 0.05.</p> <p>Results: RR technique intra-group subject analysis showed a significant decrease in LF/HF ratio (F ¼ 25.18; p < 0.001), a statistically significant decrease of LF (F ¼ 27.09; p < 0.001), and increase of HF, both at the end of treatment (F ¼ 27.09; p < 0.001). CV4 technique intra-group subject analysis showed a significant reduction of the LF/HF ratio (F ¼ 81.15; p < 0.001), a significant decrease in LF (F ¼ 38.29; p < 0.001) and a significant increase of HF, at the end of treatment (F ¼ 38.28; p < 0.001). Between-group analysis showed only a significant difference in LF/HF ratio between CV4 and PL groups (F ¼ 3.44; p ¼ 0.042).</p> <p>Discussion: Our results suggest that the application of CV4 and RR techniques favors a shift in the autonomic balance towards a parasympathetic predominant state. Thus, their use within OMT protocol, as holistic approach, might improve the outcome of the treatment of clinical neuro-vegetative conditions.</p>
Dataset related to article "The Role of Pathological Method and Clearance Definition for the Evaluation of Margin Status after Pancreatoduodenectomy for Periampullary Cancer. Results of a Multicenter Prospective Randomized Trial."
<p>This record contains data related to article "The Role of Pathological Method and Clearance Definition for the Evaluation of Margin Status after Pancreatoduodenectomy for Periampullary Cancer. Results of a Multicenter Prospective Randomized Trial."</p> <p>Background: There is extreme heterogeneity in the available literature on the determination of R1 resection rate after pancreatoduodenectomy (PD); consequently, its prognostic role is still debated. The aims of this multicenter randomized study were: to evaluate the effect of sampling and clearance definition in determining R1 rate after PD for periampullary cancer; to assess the prognostic role of R1 resection.</p> <p>Methods: PD specimens were randomized to Leeds Pathology Protocol (LEEPP) (group A) or conventional method adopted before the study (group B). R1 rate was determined adopting 0 and 1 mm clearance; the association between R1, local recurrence (LR) and overall survival (OS) was also evaluated.</p> <p>Results. One-hundred-sixty-eight PD specimens were included. With 0 mm clearance, R1 rate was 26.2% and 20.2% for groups A and B, respectively; with 1 mm, R1 rate was 60.7% and 57.1%, respectively (p > 0.05). Only in group A, R1 was found to be a significant prognostic factor: at 0 mm, median OS was 36 and 20 months for R0 and R1, respectively, while at 1 mm. median OS was not reached and 30 months. At multivariate analysis, R1 resection was found as a significant prognostic factor independent of clearance definition only in case of adoption of LEEPP.</p> <p>Conclusions. The 1 mm clearance is the most effective factor in determining R1 rate after PD. However, the pathological method is crucial to accurately evaluate its prognostic role: only R1 resections obtained with the adoption of LEEPP seem to significantly affect prognosis.</p>
Analysis of inflammatory predictors and differences in gene expression in patients with Cognitive Impairment Mild responders and non-responders to Neurostimulation: a randomized, double-blind clinical trial
<p>https://docs.google.com/spreadsheets/d/1jUrBFxUs57HBCj-y0NkID1kzdnsLPpr9/edit#gid=788062431</p> <p>Mild cognitive impairment (MCI) refers to the transition state between the cognitive changes of normal aging and early dementia, but it does not notably interfere with activities of daily living. MCI is believed to be a prodromal stage of dementia that causes severe cognitive dysfunction, so its identification for early intervention is considered an important therapeutic strategy.<br> In this context, non-pharmacological interventions, such as Transcranial Direct Current Stimulation (tDCS), which uses direct electrical currents to stimulate specific parts of the brain, have been used to clinically improve these patients. Biochemical processes have been linked to the pathogenesis of MCI and dementia, including chronic inflammation, dysregulation of membrane lipids, disruption of neurotransmitter pathways, and mutations in specific genes. Therefore, the general objective of this study is to evaluate the inflammatory and gene expression profile of patients with MCI, responders and non-responders to tDCS. This is a randomized, double-blind, sham-controlled clinical trial (ClinicalTrials.org: NCT04934423).<br> Neuropsychological tests and a sociodemographic and clinical questionnaire will be used to assess and characterize the subjects. Participants captured by the Laboratory of Studies in Aging and Neurosciences of the Federal University of Paraíba will be divided into 02 groups, each with 25 patients, totaling 50 volunteers: Active – participants who will receive real anodic current; Sham – participants who will receive simulated stimulation. Participants enrolled by eligibility criteria will be randomly allocated in a simple 1:1 ratio. The equipment parameters will be customized by Computational Modeling with the help of the Non-Invasive Brain Stimulation Simulation Program and the measurement of the head circumference. The electroencephalogram and the evaluation of polymorphisms of the genes Alpha synuclein and Neuroregulin, as well as the inflammatory mediators IL-6, Il-10 and TNF-α, will be considered as possible predictors of response. The project was evaluated by the Research Ethics Committee of the Federal University of Paraíba, obtaining the following CAAE registration: 40675220.0.0000.5188. It is expected to find improvements in the scores of general cognition and memory tests after the intervention protocol of neurostimulation with an individual dose in the group that will receive the active current, compared to the simulated neurostimulation group. As well as finding differences in the Inflammatory and Genetic profiles of those responders and non-responders to Neurostimulation.</p>
Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled trial
<p>This dataset includes raw data from the article “Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled trial”.</p> <p>In this study, we enrolled 20 patients with chronic migraine (CM) and medication overuse headache (MOH). They were hospitalized for a 7-day detoxification treatment and were randomly assigned to anodal tDCS or sham stimulation delivered over the primary motor cortex contralateral to the prevalent migraine pain side every day for 5 days. Clinical data were recorded at baseline (T0), after 1 month (T2) and 6 months (T3). EEG recording was performed at T0, at the end of the tDCS/Sham treatment, and at T2.</p> <p>At T2 and T3, we found a significant reduction in monthly migraine days (p = 0.001), which were more pronounced in the tDCS group when compared to the sham group (p = 0.016). At T2, we found a significant increase of alpha rhythm in occipital leads, which was significantly higher in tDCS group when compared to sham group. In conclusion, tDCS showed adjuvant effects to detoxification in the management of patients with CM and MOH. The EEG recording showed a significant potentiation of alpha rhythm, which may represent a correlate of the underlying changes in cortico-thalamic connections.</p>
Dataset related to article "Head down tilt 15° in experimental intracerebral hemorrhage: a randomized noninferiority safety trial"
<p>The database contains animal models MRI in DICOM and NIfTI file format</p>
Preliminary Results from The ACTyourCHANGE in Teens Protocol: A Randomized Controlled Trial Evaluating Acceptance and Commitment Therapy for Adolescents with Obesity
<p>The study shows preliminary results of “The ACTyourCHANGE in Teens” project, a Randomized Controlled Trial aimed at evaluating the efficacy of an Acceptance and Commitment Therapy-based intervention combined with treatment as usual (ACT+TAU) compared to TAU only, for improving psychological well-being, psychological distress, experiential avoidance and fusion, emotion dysregulation, and emotional eating in a sample of 34 in-patient adolescents with obesity (Body Mass Index > 97th centile). Mixed between-within 2 × 2 repeated-measures analyses of variances (ANOVAs) were carried out to examine the changes in psychological conditions of participants over time. Moderation analyses were also conducted to test whether pre-test anxiety, depression, stress, and experiential avoidance and fusion predicted emotional eating at post-test with groups (ACT+TAU vs. TAU only) as moderators. Only a significant interaction effect (time × group) from pre- to post-test (<em>p </em>= 0.031) and a significant main effect of time on anxiety (<em>p </em>< 0.001) and emotional eating (<em>p</em> = 0.010) were found. Only in the TAU only group were higher levels of depression (<em>p</em> = 0.0011), stress (<em>p</em> = 0.0012), and experiential avoidance and fusion (<em>p</em> = 0.0282) at pre-test significantly associated with higher emotional eating at post-test. Although future replication and improvements of the study may allow us to obtain more consistent results, this preliminary evidence is actually promising.</p>
Effect of Alpha Soundwave Auditory Stimulation on anxiety level on patients undergoing endodontic treatment: A Randomized Controlled Trial.
Open the record for dataset details and reuse information.
Dataset concerning A double-blind randomized controlled trial combining cognitive training (CoRe) and neurostimulation (tDCS) in the early stages of cognitive impairment
<p>This is the processed data for the manuscript " Rodella C, Bernini S, Panzarasa S, Sinforiani E, Picascia M, Quaglini S, Cavallini E, Vecchi T, Tassorelli C, Bottiroli S. A double-blind randomized controlled trial combining cognitive training (CoRe) and neurostimulation (tDCS) in the early stages of cognitive impairment. Aging Clin Exp Res. 2021 Jun 22. Epub ahead of print".</p> <p>Dataset refers to a Randomized Controlled Trial aimed to evaluate the effectiveness of a combined treatment protocol associating a computerized cognitive training (CoRe) with anodal transcranial direct current stimulation (tDCS) in early phases of cognitive impairment. The dataset contains cognitive performances in neuropsychological tests (raw scores) at baseline (T0), post-intervention (T1) and 6-months later (T2). Data highlights the efficacy of combining cognitive training and neurostimulation.</p>
Dataset related to article "Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1-2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial "
<p>This record contains raw data related to article “Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1-2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial"</p> <p>Abstract</p> <p><strong>Background: </strong> The SINODAR-ONE trial is a prospective noninferiority multicenter randomized study aimed at assessing the role of axillary lymph node dissection (ALND) in patients undergoing either breast-conserving surgery or mastectomy for T1-2 breast cancer (BC) and presenting one or two macrometastatic sentinel lymph nodes (SLNs). The endpoints were to evaluate whether SLN biopsy (SLNB) only was associated with worsening of the prognosis compared with ALND in terms of overall survival (OS) and relapse.</p> <p><strong>Methods: </strong> Patients were randomly assigned (1:1 ratio) to either removal of ≥ 10 axillary level I/II non-SLNs followed by adjuvant therapy (standard arm) or no further axillary treatment (experimental arm).</p> <p><strong>Results: </strong> The trial started in April 2015 and ceased in April 2020, involving 889 patients. Median follow-up was 34.0 months. There were eight deaths (ALND, 4; SNLB only, 4), with 5-year cumulative mortality of 5.8% and 2.1% in the standard and experimental arm, respectively (p = 0.984). There were 26 recurrences (ALND 11; SNLB only, 15), with 5-year cumulative incidence of recurrence of 6.9% and 3.3% in the standard and experimental arm, respectively (p = 0.444). Only one axillary lymph node recurrence was observed in each arm. The 5-year OS rates were 98.9% and 98.8%, in the ALND and SNLB-only arm, respectively (p = 0.936).</p> <p><strong>Conclusions: </strong> The 3-year survival and relapse rates of T1-2 BC patients with one or two macrometastatic SLNs treated with SLNB only, and adjuvant therapy, were not inferior to those of patients treated with ALND. These results do not support the use of routine ALND.</p>
Dataset related to article "Endoscopic ultrasound-guided fine-needle biopsy with or without macroscopic on-site evaluation: a randomized controlled noninferiority trial "
<p>This record contains raw data related to article “Endoscopic ultrasound-guided fine-needle biopsy with or without macroscopic on-site evaluation: a randomized controlled noninferiority trial"</p> <p>Abstract</p> <p>BACKGROUND : The advantage of using the macroscopic on-site evaluation (MOSE) technique during endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed with 22G Franseen needles has not been investigated. We aimed to compare EUS-FNB with MOSE vs. EUS-FNB performed with three needle passes. METHODS : This randomized trial involved 10 Italian referral centers. Consecutive patients referred for EUS-FNB of pancreatic or nonpancreatic solid lesions were included in the study and randomized to the two groups. MOSE was performed by gross visualization of the collected material by the endoscopists and considered adequate when a white/yellowish aggregate core longer than 10 mm was retrieved. The primary outcome was diagnostic accuracy. Secondary outcomes were specimen adequacy, number of needle passes, and safety. RESULTS : 370 patients with 234 pancreatic lesions (63.2 %) and 136 nonpancreatic lesions (36.8 %) were randomized (190 EUS-FNB with MOSE and 180 with standard EUS-FNB). No statistically significant differences were found between EUS-FNB with MOSE and conventional EUS-FNB in terms of diagnostic accuracy (90.0 % [95 %CI 84.8 %-93.9 %] vs. 87.8 % [95 %CI 82.1 %-92.2 %]; <em>P</em> = 0.49), sample adequacy (93.1 % [95 %CI 88.6 %-96.3 %] vs. 95.5 % [95 %CI 91.4 %-98 %]; <em>P</em> = 0.31), and rate of adverse events (2.6 % vs. 1.1 %; <em>P</em> = 0.28). The median number of passes was significantly lower in the EUS-FNB with MOSE group (1 vs. 3; <em>P</em> < 0.001). CONCLUSIONS : The accuracy of EUS-FNB with MOSE is noninferior to that of EUS-FNB with three needle passes. MOSE reliably assesses sample adequacy and reduces the number of needle passes required to obtain the diagnosis with a 22G Franseen needle.</p>
dataset Is positive communication sufficient to modulate procedural pain and anxiety in the emergency room? A randomized controlled trial.
<p>Our study aimed to modulate contents and delivery vector of a message regarding peripheral intravenous catheter (PIC) placement in the emergency room (ER), to test if therapeutic communication could enhance patients' comfort during minor medical procedures. This study was a 2+2 randomized controlled trial. A positive versus standard message was delivered through audio tape (double blind) in the first phase (N= 131) and through the nurse in charge of the catheter placement (single blind) in the second phase (N= 120).</p>
Dataset related to the publication by Pan et al.: A randomized clinical trial of two-staged tourniquet strategy for total knee arthroplasty
<p>Dataset related to the publication by Pan et al. 2023.</p> <p>A randomized clinical trial of two-staged tourniquet strategy for total knee arthroplasty</p>
Data related to article EFFICACY OF MINDFULNESS ADDED TO TREATMENT AS USUAL IN PATIENTS WITH CHRONIC MIGRAINE AND MEDICATION OVERUSE HEADACHE: A PHASE-III SINGLE-BLIND RANDOMIZED-CONTROLLED TRIAL (THE MIND-CM STUDY) - submitted
<p>DATA ON PATIENTS INCLUDED IN THE MIND-CM STUDY. TWO ARMS (TAU AND TAU+MIND), AND FOUR EVALUATIONS: BASELINE, 3-MONTHS, 6-MONTHS AND 12-MONTS FOLLOW-UP.</p>
Comparing Effects of Ultra Low Dose (Ethinyl Estradiol 20µg or 15µg) with Low Dose (Ethinyl Estradiol 30µg) Hormonal Pills on Lipid Discordance in Non-Obese PCOS Women: A Randomized Control Trial
<p>Ultra-low dose hormonal pills have become the favoured treatment option over low dose pills in PCOS. Existing literature shows marked heterogeneity in metabolic effects of pills with different compositions. This might have been due to improper choice of outcome variable for comparison. Total cholesterol - high density lipoprotein ratio (TC/HDL) discordance with Low Density Lipoprotein cholesterol (LDL-C) was a better marker of future risk of atherosclerotic cardio-vascular disease and stable to variations. Present study was a randomised controlled trial conducted to compare prevalence of TC/HDL and LDL discordance among non-obese PCOS women treated with hormonal pills of different compositions. Role of baseline participant features and pill composition on discordance after treatment was determined. Women were randomised into three arms, two arms receiving ultra-low dose pills (either Ethinyl Estradiol 20µg with drosperinone 3mg or Ethinyl Estradiol 15µg with gestodene 60µg) and one arm receiving low dose pill (Ethinyl Estradiol 30µg with desogestrel 150 µg). Discordance was observed in more than 1/4<sup>th</sup> participants prior to intervention. After one year of treatment less than 1/5<sup>th</sup> of participants were discordant. Ultra-low dose pill users had lower discordance, LDL and TC compared to low dose pill users after one year of treatment. Random Forest a non-linear classifier showed the highest accuracy in predicting discordance. Baseline Parameters having maximal impact on occurrence of discordance were triglyceride (TG), HOMA-IR, BMI and HDL.Ultra-low dose hormonal pills have become the favoured treatment option over low dose pills in PCOS. Existing literature shows marked heterogeneity in metabolic effects of pills with different compositions. This might have been due to improper choice of outcome variable for comparison. Total cholesterol - high density lipoprotein ratio (TC/HDL) discordance with Low Density Lipoprotein cholesterol (LDL-C) was a better marker of future risk of atherosclerotic cardio-vascular disease and stable to variations. Present study was a randomised controlled trial conducted to compare prevalence of TC/HDL and LDL discordance among non-obese PCOS women treated with hormonal pills of different compositions. Role of baseline participant features and pill composition on discordance after treatment was determined. Women were randomised into three arms, two arms receiving ultra-low dose pills (either Ethinyl Estradiol 20µg with drosperinone 3mg or Ethinyl Estradiol 15µg with gestodene 60µg) and one arm receiving low dose pill (Ethinyl Estradiol 30µg with desogestrel 150 µg). Discordance was observed in more than 1/4<sup>th</sup> participants prior to intervention. After one year of treatment less than 1/5<sup>th</sup> of participants were discordant. Ultra-low dose pill users had lower discordance, LDL and TC compared to low dose pill users after one year of treatment. Random Forest a non-linear classifier showed the highest accuracy in predicting discordance. Baseline Parameters having maximal impact on occurrence of discordance were triglyceride (TG), HOMA-IR, BMI and HDL.</p>
Dataset related to article "Stereotactic Body Radiation Therapy for Lung and Liver Oligometastases from Breast Cancer: Toxicity Data of a Prospective Non-Randomized Phase II Trial"
<p>This record contains raw data related to article "Stereotactic Body Radiation Therapy for Lung and Liver Oligometastases from Breast Cancer: Toxicity Data of a Prospective Non-Randomized Phase II Trial"</p><p>Abstract</p><p><strong>Aims: </strong>We report the mature toxicity data of a phase II non-randomized trial on the use of SBRT for lung and liver oligometastases.</p><p><strong>Methods: </strong>Oligometastatic patients from breast cancer were treated with SBRT for up to five lung and/or liver lesions. Inclusion criteria were: age > 18 years, ECOG 0-2, diagnosis of breast cancer, less than five lung/liver lesions (with a maximum diameter <5 cm), metastatic disease confined to the lungs and liver or extrapulmonary or extrahepatic disease stable or responding to systemic therapy. Various dose-fractionation schedules were used. Then, a 4D-CT scan and FDG-CTPET were acquired for simulation and fused for target definition.</p><p><strong>Results: </strong>From 2015 to 2021, 64 patients and a total of 90 lesions were irradiated. Treatment was well tolerated, with no G 3-4 toxicities. No grade ≥3 toxicities were registered and the coprimary endpoint of the study was met. Median follow-up was 19.4 months (range 2.6-73.1).</p><p><strong>Conclusions: </strong>The co-primary endpoint of this phase II trial was met, showing excellent tolerability of SBRT for lung and liver oligometastatic in breast cancer patients. Until efficacy data will mature with longer follow-up, SBRT should be regarded as an opportunity for oligometastatic breast cancer patients.</p>
Dataset related to article "Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform"
<p>This record contains raw data related to article "Radiosurgery of limited brain metastases from primary solid tumor: results of the randomized phase III trial (NCT02355613) comparing treatments executed with a specialized or a C-arm linac-based platform"</p><p>Abstract</p><p>Background: Comparative prospective data regarding different radiosurgery (SRS) modalities for treating brain metastases (BMs) from solid tumors are not available. To investigate with a single institute phase III randomized trial whether SRS executed with linac (Arm-B) is superior to a dedicated multi-source gamma-ray stereotactic platform (Arm-A).</p><p>Methods: Adults patients with 1-4 BMs from solid tumors up to 30 mm in maximum diameter were randomly assigned to arms A and B. The primary endpoint was cumulative incidence of symptomatic (grade 2-3) radionecrosis (CIRN). Secondary endpoints were local progression cumulative incidence (CILP), distant brain failure, disease-free survival (DFS), and overall survival (OS).</p><p>Results: A total of 251 patients were randomly assigned to Arm-A (121) or Arm-B (130). The 1-year RN cumulative incidence was 6.7% in whole cohort, 3.8% (95% CI 1.9-7.4%) in Arm-B, and 9.3% (95% CI 6.2-13.8%) in the Arm-A (p = 0.43). CIRN was influenced by target volume irradiated only for the Arm-A (p << 0.001; HR 1.36 [95% CI 1.25-1.48]). Symptomatic RN occurred in 56 cases at a median time of 10.3 months (range 1.15-54.8 months), 27 in the Arm-B at a median time of 15.9 months (range 4.9-54.8 months), and 29 in the Arm-A at a median time of 6.9 months (1.2-32.3 months), without statistically significant differences between the two arms. No statistically significant differences were recorded between the two arms in CILP, BDF, DFS or OS. The mean beam-on time to deliver SRS was 49.0 ± 36.2 min in Arm-A, and 3.1 ± 1.6 min in Arm-B.</p><p>Conclusions: Given the technical differences between the treatment platforms investigated in this single-institution study, linac-based SRS (Arm-B) did not lead to significantly lower grade 2-3 RN rates versus the multi-source gamma-ray system (Arm-A) in a population of patients with limited brain metastases of small volume. No significant difference in local control was observed between both arms. For Arm-B, the treatment delivery time was significantly lower than for Arm-A.</p><p> </p><p>Trial registration: ClinicalTrials.gov Identifier NCT02355613.</p><p> </p>
A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of an HIV-1 Pseudovirion Vaccine
ClinicalTrials.gov study NCT00000835. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Implementing whole genome array for clinical use in academic centers: A randomized trial comparing neoadjuvant standard chemotherapy to genomic-driven chemotherapy in operable breast cancer (REMAGUS04
GEO Series GSE63471. Homo sapiens. 142 samples. Type: Expression profiling by array.
Effects of β2-receptor stimulation by indacaterol in chronic heart failure treated with selective or non-selective β-blockers: a randomized trial
<p>Raw data of the paper: <strong>Effects of β<sub>2</sub>-receptor stimulation by indacaterol in chronic heart failure treated with selective or non-selective β-blockers: a randomized trial</strong></p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.