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237 results for “Antifungals”
Fig. 5 in Identification, characterization, and antifungal activity of cysteine peptidases from Calotropis procera latex
Fig. 5. Atomic force microscopic images of Fusarium oxysporum spores treated with the three cysteine peptidases from Calotropis procera (CpCP1, CpCP2 and CpCP3). The changes in the cell morphology (gray arrows) and the leakage of cellular (white arrows) content in the vicinity of the spores treated with peptidases can be observed. Peptidases (50 μg/ mL) were incubated with spore suspensions for 30 min at 27 ̊C. Control: 50 mM sodium phosphate buffer (pH 7.0).
Data from: Phase-dependent differential in vitro and ex vivo susceptibility of Aspergillus flavus and Fusarium keratoplasticum to azole antifungals
<p>Fungal keratitis (FK) is an invasive infection of the cornea primarily associated with <em>Aspergillus</em> and <em>Fusarium</em> species. FK is treated empirically with a limited selection of topical antifungals with varying levels of success. Though clinical infections are typically characterized by a dense network of mature mycelium, traditional models used to test antifungal susceptibility of FK isolates exclusively evaluate susceptibility in fungal cultures derived from asexual spores known as conidia. The purpose of this study was to characterize differences in fungal response when topical antifungal treatment is initiated at progressive phases of fungal development. We compared efficacy of voriconazole and luliconazole against <em>in vitro</em> cultures of <em>A. flavus</em> and <em>F. keratoplasticum</em> at 0, 24, and 48 h of fungal development. Data from this assay is included here, reported as end-point absorbance values. A porcine cadaver corneal model was used to compare antifungal efficacy of voriconazole and luliconazole in <em>ex vivo</em> tissue cultures of <em>A. flavus</em> and <em>F. keratoplasticum</em> at 0, 24, and 48 h of fungal development. Data from this assay may be found here, reported as pixel counts of the determined area.</p>
Uptake of the Antifungal Miconazole and Effect on Estrogen Metabolizing Enzymes in Humans
ClinicalTrials.gov study NCT00668538. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Empirical Antifungal Treatment in ICUS
ClinicalTrials.gov study NCT01773876. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A B-D-Glucan Driven Antifungal Stewardship Approach for Invasive Candidiasis
ClinicalTrials.gov study NCT03090334. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Diagnosing Invasive Aspergillosis by Polymerase Chain Reaction (PCR) Based Investigation of Bronchoalveolar Lavage Samples During Antifungal Therapy
ClinicalTrials.gov study NCT01448226. IPD Sharing: Not stated. Countries: 2. Publications: 4.
Serial Therapeutic and Antifungal Monitoring Protocol
ClinicalTrials.gov study NCT02163889. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fungal Biomarkers to Reduce Duration of Empirical Antifungal Therapy: a Randomized Comparative Study (STAFE)
ClinicalTrials.gov study NCT02154178. IPD Sharing: NO. Countries: 1. Publications: 1.
Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapy
ClinicalTrials.gov study NCT00413439. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Disease
ClinicalTrials.gov study NCT01950507. IPD Sharing: Not stated. Countries: 1. Publications: 3.
PET/CT Guided Antifungal Stewardship in Invasive Pulmonary Aspergillosis
ClinicalTrials.gov study NCT02955966. IPD Sharing: NO. Countries: 1. Publications: 11.
Comparison of 2 Antifungal Treatment (Empirical Versus Pre-Empirical) Strategies in Prolonged Neutropenia
ClinicalTrials.gov study NCT00190463. IPD Sharing: Not stated. Countries: 1. Publications: 1.
PEACE: Pediatric Antifungal Comparative Effectiveness
ClinicalTrials.gov study NCT01869829. IPD Sharing: Not stated. Countries: 8. Publications: 1.
A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults
ClinicalTrials.gov study NCT00250432. IPD Sharing: YES. Countries: 0. Publications: 1.
Antifungal Use in Oncohematological Neutropenic Patients
ClinicalTrials.gov study NCT00386802. IPD Sharing: Not stated. Countries: 1. Publications: 37.
Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients
ClinicalTrials.gov study NCT01495039. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Revision of Antifungal Strategies Definitions for Invasive Fungal Infections in Hematological Malignancies
ClinicalTrials.gov study NCT04024995. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Glucosamine Sulphate and Ginkgo Biloba as Antifungal Activity for Treating Tinea Pedis
ClinicalTrials.gov study NCT02882438. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Seifem Surveillance of Antifungal Combination Therapy In Hematologic Italian Centers
ClinicalTrials.gov study NCT00906633. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Empirical Versus Preemptive Antifungal Therapy
ClinicalTrials.gov study NCT01288378. IPD Sharing: Not stated. Countries: 6. Publications: 1.
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