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ShareScore release 0.9.0
Dataset results
60 results for “Aortic valve disease”
TAVR for Aortic Valve Disease
ClinicalTrials.gov study NCT05439863. IPD Sharing: NO. Countries: 1. Publications: 0.
Identification of Genetic Causes of Calcific Aortic Valve Disease
ClinicalTrials.gov study NCT04149600. IPD Sharing: NO. Countries: 1. Publications: 0.
Severe Aortic Valve Stenosis and Concomitant Coronary Artery Disease in Patients Undergoing TAVI
ClinicalTrials.gov study NCT04385459. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Fate at Long-term of Mild to Moderate Bicuspid Aortic Valve Disease Left Untreated at the Time of Supracoronary Ascending Aorta Replacement
ClinicalTrials.gov study NCT05836363. IPD Sharing: NO. Countries: 1. Publications: 0.
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
ClinicalTrials.gov study NCT04634240. IPD Sharing: NO. Countries: 2. Publications: 0.
Identification of Genetic Causes of Bicuspid Aortic Valve Disease
ClinicalTrials.gov study NCT01026571. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Raloxifene Attenuates Gas6 and Apoptosis in Experimental Aortic Valve Disease in Renal Failure
GEO Series GSE21771. Rattus norvegicus. 4 samples. Type: Expression profiling by array.
Inhibitory Role of Notch1 in Calcific Aortic Valve Disease
GEO Series GSE31668. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
Partial dataset related to the article "Sport PRactice and its Effects on aortic size and valve function in bicuspid Aortic valve Disease: a cross-sectional report from the SPREAD study".
<p>This record contains raw data related to the article "<span>Sport PRactice and its Effects on aortic size and valve function in bicuspid Aortic valve Disease: a cross-sectional report from the SPREAD study"</span></p> <p><span>The bicuspid aortic valve (BAV) is the most common congenital heart defect among adults, often leading to severe valve dysfunction and aortic complications. Despite its clinical significance, uncertainties persist regarding the impact of sports participation on the natural course of BAV disease. The SPREAD (Sport PRactice and its Effects on Bicuspid Aortic valve Disease) study is a multicenter and multinational project designed to investigate this relationship. This paper outlines the study's design, and objectives. The study is divided into two phases; phase one involves a cross-sectional analysis comparing aortic dimensions and valve function among competitive athletes with BAV, athletes with tricuspid aortic valves (TAV), and sedentary individuals with BAV. The second phase is a prospective, longitudinal follow-up aiming to evaluate the impact of regular sports training on disease progression. The SPREAD study seeks to provide evidence-based insights into the effects of sports participation on BAV disease progression, guiding clinical decision-making regarding sports eligibility and risk stratification for individuals with BAV.</span></p>
Clinical Trial Evaluating the Safety and Efficacy of Artificial Polymer Heart Valve for the Treatment of Aortic Valve Disease
ClinicalTrials.gov study NCT06737757. IPD Sharing: Not stated. Countries: 0. Publications: 0.
A Multicenter, Prospective, Randomized Controlled Trial to Evaluate the Efficacy of PCSK-9 Inhibitors in Delaying the Progression of Calcified Aortic Valve Disease
ClinicalTrials.gov study NCT06996223. IPD Sharing: YES. Countries: 0. Publications: 0.
Comparative Analysis of Stented Biological Prosthesis Versus Aortic Allograft in Patients With Degenerative Aortic Valve Disease
ClinicalTrials.gov study NCT07210541. IPD Sharing: NO. Countries: 0. Publications: 0.
Ablation of the Sost gene prevents hallmarks of calcific aortic valve disease in a high-cholesterol mouse model
GEO Series GSE190295. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A novel long noncoding RNA SNHG3 promotes osteoblast differentiation through BMP2 upregulation in calcific aortic valve disease
GEO Series GSE199718. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
Toll-like receptor 3 mediates calcific aortic valve disease via a conserved mechanism of calcification
GEO Series GSE138360. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
piRNAs dysregulated in calcific aortic valve disease
GEO Series GSE214630. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The alterations of gene expression in aortic valve from calcific aortic valve disease patients
GEO Series GSE77287. Homo sapiens. 6 samples. Type: Expression profiling by array.
Circulating monocytes from patients promote calcific aortic valve disease development
GEO Series GSE290104. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Dysregulated microRNAs in calcific aortic valve disease
GEO Series GSE87885. Homo sapiens. 5 samples. Type: Non-coding RNA profiling by array.
Aortic Valve Sclerosis in High-Risk Coronary Artery Disease Patients
<p>This record contains raw data related to the article “Aortic Valve Sclerosis in High-Risk Coronary Artery Disease Patients”<strong>Background:</strong> Current knowledge regarding the relationship between aortic valve sclerosis (AVSc), cardiovascular risk factors, and mortality in patients with known coronary artery disease (CAD) is still unclear. The present study aimed at investigating the prevalence of AVSc as well as its association with long-term all-cause mortality in high-risk CAD patients that has never been explored in large cohorts thus far. <strong>Methods and Results:</strong> In this retrospective and observational cohort study we enrolled high-risk CAD patients, hospitalized at Centro Cardiologico Monzino (CCM), Milan, Italy, between January 2006 and December 2016. The morphology and function of the aortic valve were assessed from the recorded echocardiographic images to evaluate the presence of AVSc, defined as a non-uniform thickening of the aortic leaflets with no consequences on hemodynamics. Data on 5-year all-cause mortality was retrieved from a Regional database. Of the 5,489 patients initially screened, 4,938 (mean age 67 ± 11 years, 3,954 [80%] men) were enrolled in the study. In the overall population, AVSc was detected in 2,138 (43%) patients. Multivariable LASSO regression revealed that age, female gender, diabetes mellitus, previous MI, and left ventricular ejection fraction were independently associated with AVSc. All-cause mortality (adjusted hazard ratio: 1.29, 95%CI: 1.05-1.58) was significantly higher in AVSc than in non-AVSc patients. <strong>Conclusions:</strong> AVSc is frequently detected in high-risk CAD patients and is associated with long-term mortality. Our findings corroborate the hypothesis that AVSc is an underestimated marker of systemic cardiovascular risk. Thus, AVSc detection may be used to improve long-term risk stratification of high-risk CAD patients.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.