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126
datasets available to search
ShareScore release 0.9.0
Dataset results
126 results for “BDNF”
Sex-based differences in cardiac gene expression and function in BDNF Val66Met mice
GEO Series GSE178685. Mus musculus. 31 samples. Type: Expression profiling by high throughput sequencing.
PRPF40B regulates NTRK2 pre-mRNA splicing to control its dominant-negative receptor, preventing BDNF signaling inhibition in neurons
GEO Series GSE293518. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
A BDNF-TrkB autocrine loop enhances senescent cell viability [scRNA-seq]
GEO Series GSE202950. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
A BDNF-TrkB autocrine loop enhances senescent cell viability
GEO Series GSE202951. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.
The Intermittent Fasting Mimetic, 2-deoxyglucose, Reprograms Brain Derived Neurotrophic Factor (BDNF) transcription via an Adaptive ER Stress-ATF4 Pathway and Improves Outcomes in Alzheimer’s and Stro
GEO Series GSE217284. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Neuronal activity induced by BDNF prompts chromatin remodeling at regulatory elements associated with neuropsychiatric traits [mouse]
GEO Series GSE166959. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A BDNF-TrkB autocrine loop enhances senescent cell viability [RNA-seq]
GEO Series GSE190998. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Long non-coding RNA in neurons: new players in early response to BDNF stimulation
GEO Series GSE78055. Homo sapiens. 6 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Epigenetic intersection of BDNF Val66Met genotype with premenstrual dysphoric disorder transcriptome in a cross-species model of estradiol add-back
GEO Series GSE121412. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
BDNF secreted by mesenchymal stem cells improves the quality and development potential of aged oocytes by activating the ERK1/2 signaling pathway
GEO Series GSE263864. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
The Intermittent Fasting Mimetic, 2-deoxyglucose, Reprograms Brain Derived Neurotrophic Factor (BDNF) transcription via an Adaptive ER Stress-ATF4 Pathway and Improves Outcomes in Alzheimer’s and Stro
GEO Series GSE217282. Mus musculus. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Analysis of human neurotrophins and receptors in bone marrow stromal cells (BMSC) treated with NGF or BDNF
GEO Series GSE18537. Homo sapiens. 3 samples. Type: Expression profiling by array.
Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis
GEO Series GSE250436. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing; Other.
Glioma synapses recruit mechanisms of adaptive plasticity: Gene expression changes induced by BDNF treatment in SU-DIPGVI in vitro
GEO Series GSE222481. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1
GEO Series GSE122176. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels.
GEO Series GSE136253. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Stat3-Bdnf-TrkB axis promotes alveolar regeneration [scRNA-seq]
GEO Series GSE132533. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Gel-electrophoresis of subjects' BDNF genotyping PCR
<p>Supplementary Figure of BDNF genotyping</p>
Mild behavioral impairment in early Alzheimer's disease and its association with APOE and BDNF risk genetic polymorphisms
<p>Mild behavioral impairment (MBI) has been commonly reported in early Alzheimer’s disease (AD) but rarely using biomarker-defined samples. It is also unclear whether genetic polymorphisms influence MBI in such individuals. We thus aimed to examine the association between the cognitive status of participants (amnestic mild cognitive impairment (aMCI-AD) vs cognitively normal (CN) older adults) and MBI severity. Within aMCI-AD, we further examined the association between APOE and BDNF risk genetic polymorphisms and MBI severity.</p> <p>We included 62 aMCI-AD participants and 50 CN older adults from the Czech Brain Aging Study. The participants underwent neurological, comprehensive neuropsychological examination, APOE and BDNF genotyping, and magnetic resonance imaging. MBI was diagnosed with the Mild Behavioral Impairment Checklist (MBI-C), and the diagnosis was based on the MBI-C total score ≥ 7. Additionally, self-report instruments for anxiety (the Beck Anxiety Inventory) and depressive symptoms (the Geriatric Depression Scale-15) were administered. The participants were stratified based on the presence of at least one risk allele in genes for APOE (i.e., e4 carriers and non-carriers) and BDNF (i.e., Met carriers and non-carriers). We used linear regressions to examine the associations.</p> <p>MBI was present in 48.4% of the aMCI-AD individuals. Compared to the CN, aMCI-AD was associated with more affective, apathy, and impulse dyscontrol but not social inappropriateness or psychotic symptoms. Furthermore, aMCI-AD was related to more depressive but not anxiety symptoms on self-report measures. Within the aMCI-AD, there were no associations between <em>APOE</em> e4 and <em>BDNF</em> Met and MBI-C severity. However, a positive association between Met carriership and self-reported anxiety appeared.</p> <p>MBI is frequent in aMCI-AD and related to more severe affective, apathy, and impulse dyscontrol symptoms. <em>APOE</em> and <em>BDNF</em> polymorphisms were not associated with MBI severity separately; however, their combined effect warrants further investigation.</p>
Epigenetic Regulation of BDNF in Schizophrenia
ClinicalTrials.gov study NCT01021449. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.