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90 results for “Balancing selection”
Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.
ClinicalTrials.gov study NCT06401941. IPD Sharing: NO. Countries: 1. Publications: 1.
Effect of PNF on Selective Motor Control and Balance in CP
ClinicalTrials.gov study NCT05649501. IPD Sharing: NO. Countries: 1. Publications: 6.
Data from: A tight balance between natural selection and gene flow in a southern African arid-zone endemic bird
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Data from: Low major histocompatibility complex class II variation in the endangered Indo-Pacific humpback dolphin (Sousa chinensis): inferences about the role of balancing selection
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Data from: Balancing selection and introgression of newt immune-response genes
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Data from: Major histocompatibility complex class II variation in bottlenose dolphin from Adriatic Sea: inferences about the extent of balancing selection
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Balancing selection in Pattern Recognition Receptor signalling pathways is associated with gene function and pleiotropy in a wild rodent
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Data from: Extensive variation at MHC DRB in the New Zealand sea lion (Phocarctos hookeri) provides evidence for balancing selection
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Data from: A treefrog with reproductive mode plasticity reveals a changing balance of selection for non-aquatic egg-laying
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Data from: Genetics and evidence for balancing selection of a sex-linked colour polymorphism in a songbird
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Data from: “Balancing” balancing selection? Assortative mating at the major histocompatibility complex despite molecular signatures of balancing selection
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Data from: Lack of spatial immunogenetic structure among wolverine (Gulo gulo) populations suggestive of broad scale balancing selection
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Data from: Cast adrift on an island: introduced populations experience an altered balance between selection and drift
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Data from: Long-term balancing selection on chromosomal variants associated with crypsis in a stick insect
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Data from: Multilocus patterns of genetic variation across Cryptosporidium species suggest balancing selection at the gp60 locus
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Data from: Natural selection on MHC IIβ in parapatric lake and stream stickleback: balancing, divergent, both or neither?
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Balancing selection and drift in a polymorphic salamander metapopulation
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Data from: Beyond balancing selection: frequent mitochondrial recombination contributes to high female frequencies in gynodioecious Lobelia siphilitica L. (Campanulaceae)
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Data for: Immigration counter-acts local micro-evolution of a major fitness component: migration-selection balance in free-living song sparrows
<p>Ongoing adaptive evolution, and resulting 'evolutionary rescue' of declining populations, requires additive genetic variation in fitness. Such variation can be increased by gene flow resulting from immigration, potentially facilitating evolution. But, gene flow could in fact constrain rather than facilitate local adaptive evolution if immigrants have low additive genetic values for local fitness. Local migration-selection balance and micro-evolutionary stasis could then result. However, key quantitative genetic effects of natural immigration, comprising the degrees to which gene flow increases the total local additive genetic variance yet counter-acts local adaptive evolutionary change, have not been explicitly quantified in wild populations. Key implications of gene flow for population and evolutionary dynamics consequently remain unclear. Our quantitative genetic analyses of long-term data from free-living song sparrows (<i>Melospiza melodia</i>) show that mean breeding value for local juvenile survival to adulthood, a major component of fitness, increased across cohorts more than expected solely due to drift. Such micro-evolutionary change should be expected given non-zero additive genetic variance and consistent directional selection. However, this evolutionary increase was counter-acted by negative additive genetic effects of recent immigrants, which increased total additive genetic variance but prevented a net directional evolutionary increase in total additive genetic value. These analyses imply an approximate quantitative genetic migration-selection balance in a major fitness component, and hence demonstrate a key mechanism by which substantial additive genetic variation can be maintained yet decoupled from local adaptive evolutionary change.</p>
Data from: Evolution of quantitative traits under a migration-selection balance: when does skew matter?
Quantitative-genetic models of differentiation under migration-selection balance often rely on the assumption of normally distributed genotypic and phenotypic values. When a population is subdivided into demes with selection toward different local optima, migration between demes may result in asymmetric, or skewed, local distributions. Using a simplified two-habitat model, we derive formulas without a priori assuming a Gaussian distribution of genotypic values, and we find expressions that naturally incorporate higher moments, such as skew. These formulas yield predictions of the expected divergence under migration-selection balance that are more accurate than models assuming Gaussian distributions, which illustrates the importance of incorporating these higher moments to assess the response to selection in heterogeneous environments. We further show with simulations that traits with loci of large effect display the largest skew in their distribution at migration-selection balance.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.