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660 results for “Biomechanics”
FIGURE 3. 3.1 von Mises stresses, 3.2 von Mises strains, 3.3 Displacements, 3.4 von Mises stress relationship with reference value, 3.5 von Mises strain relationship with reference value and 3.6 in Insights into the controversy over materials data for the comparison of biomechanical performance in vertebrate
FIGURE 3. 3.1 von Mises stresses, 3.2 von Mises strains, 3.3 Displacements, 3.4 von Mises stress relationship with reference value, 3.5 von Mises strain relationship with reference value and 3.6 Displacement relationship with reference value in front of variation in the elastic modulus (E) in points P and Q.
FIGURE 2 in Insights into the controversy over materials data for the comparison of biomechanical performance in vertebrate
FIGURE 2. von Mises Stress Distribution, von mises strain distribution and Displacement field distribution for Connochaetes taurinus and Alcelaphus buselaphus when elastic modulus is E=10000 MPa, E=25000 MPa and E=50000 MPa for a homogeneous material (case A).
FIGURE 5. 5.1 von Mises stresses, 5.2 von Mises strains, 5.3 Displacements, 5.4 von Mises stress relationship with reference value, 5.5 von Mises strain relationship with reference value and 5.6 in Insights into the controversy over materials data for the comparison of biomechanical performance in vertebrate
FIGURE 5. 5.1 von Mises stresses, 5.2 von Mises strains, 5.3 Displacements, 5.4 von Mises stress relationship with reference value, 5.5 von Mises strain relationship with reference value and 5.6 Displacement relationship with reference value in front of variation in the elastic modulus (E) in points P and Q.
FIGURE 1 in Insights into the controversy over materials data for the comparison of biomechanical performance in vertebrate
FIGURE 1. Boundary conditions, forces applied in the studied jaws, location of points P and Q and separated regions where the Non-homogeneous properties are applied for the Connochaetes taurinus and Alcelaphus buselaphus.
FIGURE 4 in Insights into the controversy over materials data for the comparison of biomechanical performance in vertebrate
FIGURE 4. von Mises Stress Distribution, von Mises strain distribution and displacement field distribution for Connochaetes taurinus and Alcelaphus buselaphus when elastic modulus is E=10000 MPa, E=25000 MPa and E=50000 MPa for a non-homogeneous material (case B).
Biomechanical filtering supports efficient tactile encoding in the human hand
<p>This repository contains the data and code used to produce the results in the publication "Biomechanical filtering supports efficient tactile encoding in the human hand." If you use these data or code, please cite our publication.</p> <p>Full citation: N. Tummala, G. Reardon, B. Dandu, Y. Shao, H. P. Saal, and Y. Visell, "Biomechanical filtering supports efficient tactile encoding in the human hand". bioRxiv, 2024. doi: 10.1101/2023.11.10.565040</p> <p> </p> <p><strong>Abstract From Manuscript</strong></p> <p>Touching an object elicits skin oscillations that are biomechanically transmitted throughout the hand, driving responses in thousands of tactile receptors, including numerous exquisitely sensitive Pacinian corpuscles (PCs). Accepted descriptions of PC functionality characterize their response properties as highly stereotyped, based on experimental data gathered when stimuli are applied near the receptor. However, during natural touch, spiking activity in the majority of PCs is evoked by transmitted skin oscillations that are modified by biomechanical filtering. This filtering mechanism, stemming from dispersive wave dynamics in the skin, bears some similarity to the pre-neuronal filtering of auditory signals by the basilar membrane, a mechanical process that is instrumental to perception. Thus, we sought to clarify how skin biomechanics might influence tactile information encoding in the periphery. We used vibrometry imaging and computational neural experiments to examine the influence of biomechanical filtering on neural activity in whole-hand PC populations. We observed complex, location- and frequency-dependent patterns of filtering that were shaped by tissue mechanics and hand morphology. This source of biomechanical modulation diversified PC population spiking activity and enhanced tactile information encoding efficiency. These findings indicate that biomechanics furnishes a pre-neuronal mechanism that facilitates efficient tactile encoding and processing.</p> <p> </p>
Evaluation of design parameters on the outcome of intrastromal ring surgery using biomechanical simulations
<p><strong><a title="Evaluation of design parameters on the outcome of intrastromal ring surgery using biomechanical simulations" href="../records/13377029?preview=1&token=eyJhbGciOiJIUzUxMiJ9.eyJpZCI6IjUzYjY5ZWY4LTgzZTctNDUyMi05MDkxLTJjZjBlMWMxMzYxOCIsImRhdGEiOnt9LCJyYW5kb20iOiI4MmRhMThhNjlkZGE4NTg5OWQ1MDRlZWYxNjIwZmU3MCJ9.DuFue1sYgSBRo9k0tqSJKkh3gKyZaIbvn0i4MupXLei0aBMYdhYX05ZPjMhDdn6ufu0M4tgxRkmNbxdQkwzI4A">10.5281/zenodo.13377029 </a>Background</strong>: The cornea plays a role in the refractive power of the eye, and when its natural curvature and thickness are compromised by diseases such as keratoconus or high myopia, this results in loss of visual acuity. Intracorneal rings (ICRs) were developed as a treatment option to restore the natural corneal curvature by implanting rings into tunnels cut within the corneal stroma. However, selecting and placing the appropriate ring can be difficult, and predicting refractive outcomes is challenging.</p> <p><strong>Objective</strong>: The purpose of this study was to better understand the design parameters of the rings that determine postoperative refractive and mechanical outcomes.</p> <p><strong>Methods</strong>: We developed an automated finite element simulation pipeline for ICR implantation and tested 300 variations of 20 ICRs.</p> <p><strong>Results</strong>: The outcome of ICR was dominated by the vertical size of the ring; 84% of the change in corneal curvature can be attributed to the vertical size of the ring, while only 13% were attributed to the detailed cross-sectional shape of the ring. However, the cross-sectional shape of the ring is limited to the change in axial length and contact pressure between the ring and the cornea. The horizontal dimension of the ring plays only a minor role in the postoperative outcome.</p> <p><strong>Conclusion</strong>: These results support Keraring's approach to ring scaling, in which only the vertical dimension of the ring is changed, while the horizontal dimension remains constant. Numerical models help to understand ICR outcomes, design implants, and personalize empirical nomograms to achieve more successful postoperative outcomes.</p>
Figure 16 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 16. Distal epiphysis of left ulnae of Simocyon batalleri from batallones-1 (A), Gulo gulo (B) and Potos flavus (C); arrows indicate the distal end of the attachment surface for the pronator quadratus muscle. The bones are illustrated at the same size.
Figure 15 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 15. Cranial view of the distal epiphysis of a humerus of Simocyon batalleri from Batallones-1, showing the attachment areas of the main flexor muscles of the forearm: p.t., pronator teres; f.c.r., flexor carpi radialis; f.d.s. + f.d.p.cu, common area of flexor digitorum superficialis and condilo-ulnaris branch of the flexor digitorum profundus; f.d.p.c, centralis branch of the flexor digitorum profundus; f.d.p.cr, condilo-radialis branch of the flexor digitorum profundus p.l., palmaris longus; and f.c.u., flexor carpi ulnaris.
Figure 8 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 8. Lateral (top row) and medial (bottom row) views of selected right metacarpals of Simocyon batalleri from Batallones-1: A and F, B-2248, Mc V; B and G, B/S-218, Mc IV; C and H, B-2526(3), Mc III; D and I, B-1956, Mc II; and E and J, B-3684, Mc I.
Figure 7 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 7. Articulated metapodials of Simocyon batalleri from Batallones-1 in dorsal view: A, right metacarpals; B, left metatarsals.
Figure 5 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 5. Long bones of Simocyon batalleri from Batallones-1: A–D, B-2390, right humerus in lateral (A), caudal (B), medial (C) and cranial (D) views; E–F, B-438, left ulna in lateral (E) and medial (F) views; and G–H, B-3680, right radius in medial (G) and lateral (H) views.
Figure 19 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 19. Skeletal reconstruction of Simocyon batalleri. The pelvis, femora, tibiae, fibulae, sacrum and caudal vertebrae are not known in the Batallones-1 sample, and have been reconstructed on the basis of Ailurus fulgens (artwork by M. Antón).
Figure 6 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 6. Carpals of Simocyon batalleri from Batallones-1: A–B, B-5449, left unciform in dorsal (A) and medial (B) views; C–D, B-1767(2), right magnum in medial (C) and lateral (D) views; E–F, B-5441, left radial sesamoid in dorsal (E) and lateral (F) views; G–H, B-1575, right trapezoid in distal (G) and proximal (H) views; I–J, B-250, right pyramidal in medial (I) and lateral (J) views; K–L, right scapholunar in proximal (K) and distal (L.) views; M–N, B-2264, pisiform in proximal (M) and dorsal (N) views.
Figure 11 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 11. Tarsals of Simocyon batalleri from Batallones-1: A–B, B-608, right ectocuneiform in proximal (A) and lateral (B) views; C–D, B/S-405, right cuboid in dorsal (C) and medial (D) views; E–F, B-2497, left calcaneus in medial (E) and plantar (F) views; G–H, B-2496, left navicular in distal (G) and proximal (H) views; I–J, B-2526(8), left mesocuneiform in lateral (I) and medial (J) views; and K–L, B-1061, left astragalus in plantar (K) and dorsal (L.) views.
Figure 1 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 1. Skull (top) and life appearance (bottom) of Simocyon batalleri, based on the fossils from Batallones-1 (artwork by M. Antón).
Figure 2 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 2. Cervical vertebrae of Simocyon batalleri from Batallones-1. A–C, B-7038, third cervical vertebra in cranial (A), lateral (B) and dorsal (C) views; D–E, B-2188, fourth cervical vertebra in dorsal (D) and cranial (E) views; F–G, B-1767(1), sixth cervical vertebra in lateral (F) and cranial (G) views; and H–I, B-1676(3), seventh cervical vertebra in cranial (H) and lateral (I) views.
Figure 3. B-429 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 3. B-429, articulated third to sixth lumbar vertebrae of Simocyon batalleri from Batallones-1: A, lateral, B, dorsal views.
Figure 18 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 18. Dorsal views of articulated left calcaneus and astragalus of Ailuropoda melanoleuca (A), Ailurus fulgens (B), Simocyon batalleri from Batallones-1 (C), Gulo gulo (D) and Potos flavus (E).
Figure 17 in Functional anatomy and biomechanics of the postcranial skeleton of Simocyon batalleri (Viret, 1929) (Carnivora, Ailuridae) from the Late Miocene of Spain
Figure 17. Medial view of the right radius of Simocyon batalleri from batallones-1 (A), Gulo gulo (B) and Potos flavus (C) showing the proximal torsion observed in S. batalleri and P. flavus. The bones are illustrated at the same size.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.