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1,242 results for “Cell proliferation”
Data_supplemental figure 7_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 7 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S7). Corresponding raw data obtained from xCELLigence provided as six files in CSV format (31003A-179400_date_examiner_17BHSD12_9_3-4_1-3). All further experiment related information and subsequent data analysis provided as a) two meta-data-file 31003A-179400_ date_examiner_17BHSD12_9_3-4_M_1) as TXT format.</p>
Data_supplemental figure 3_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 3 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S3). Corresponding raw data from a) western blot and densitometry provided as 11 files in CSV format (31003A-179400_date_examiner_17BHSD12_2_18-20_1-3) b) cellomics HTC array scan analysis provided as four files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_13_1-4). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/8_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 6_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 6 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S6). Corresponding raw data from a-c) cellomics HTC array scan analysis provided as 19 files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_14-17_1-5), d) western blot and densitometry provided as five files in CSV format (31003A-179400_date_examiner_17BHSD12_2_21_1-5). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/8_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_Figure 1_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of figure 1 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1007_s00018-019-03227-w_CMLS_Fig1). Corresponding raw data obtained from a) cellomics HTC array scan analysis provided as seven files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_1_1-7), b) raw data obtained from proliferation investigation on xCELLigence provided as one (31003A-179400_date_examiner_17BHSD12_9_1_1) file in CSV format. All further experiment related information and subsequent data analysis provided as two meta-data-files as TXT format (31003A-179400_date_examiner_17BHSD12_8/9_1_M_1).</p>
Data_supplemental figure 10_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 10 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S10). Corresponding raw data obtained from a/b) western blot and densitometry provided as 20 files in CSV format (31003A-179400_date_examiner_17BHSD12_2_27-30_1-5), c) mRNA content analyzed by RT-PCR provided as 10 files in CSV format (31003A-179400_date_examiner_17BHSD12_1_11-12_1-6). d) RT-PCR provided as 10 files in CSV format (31003A-179400_date_examiner_17BHSD12_1_13_1-4). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_1/2_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 9_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 9 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S9). Corresponding raw data obtained from a) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_23_1-5); b) Cellomics HTC array scan analysis provided as eight files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_19-20_1-5); c) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_26_1-3), d) mRNA content analyzed by RT-PCR provided as 10 files in CSV format (31003A-179400_date_examiner_17BHSD12_1_9-10_1-6), e) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_25_1-3), f) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_24_1-3) All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_1/2/8_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 8_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 8 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S8). Corresponding raw data obtained from a) cellomics HTC array scan analysis provided as five files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_18_1-5); b) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_22_1-4), investigation of migration on xCELLigence provided as four (31003A-179400_date_examiner_17BHSD12_9_5_1) files in CSV format. All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/8/9_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 5_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 5 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S5). Corresponding raw data from immunofluorescence measurements provided as three files (31003A-179400_20190528_MT, PST, ADU_17BHSD12_13_2_1-3) in png format. All further experiment related information protocols and subsequent data analysis provided as meta-data-file (31003A-179400_date_examiner_17BHSD12_13_2_M_1) as TXT format.</p>
Data_supplemental figure 1_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 1 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S1). (31003A-179400_date_examiner_17BHSD12_2_14-17) PNG format. All further experiment related information protocols as meta-data-files (31003A-179400_date_examiner_17BHSD12_2_dataset_M_1) as TXT format.</p>
Data_Figure 8_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of figure 8 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. 8). Corresponding raw data obtained from a1/2) Western blot and densitometry provided as three files in CSV format (31003A-179400_date_examiner_17BHSD12_2_9_1-3), mRNA content analyzed by RT-PCR provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_1_7_1-4); b) Western blot and densitometry provided as three files in CSV format (31003A-179400_date_examiner_17BHSD12_2_10-11_1-3); c1/2) mRNA content analyzed by RT-PCR provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_1_8_1-4), d1/2) Western blot and densitometry provided as seven files in CSV format (31003A-179400_date_examiner_17BHSD12_2_12-13_1-4). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/1_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 4_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 4 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S4). Corresponding raw data from immunofluorescence measurements provided as three files (31003A-179400_date_examiner_17BHSD12_13_1_1-3) in png format. All further experiment related information protocols and subsequent data analysis provided as meta-data-file (31003A-179400_date_examiner_17BHSD12_13_1_M_1) as TXT format.</p>
Supplementary PyMOL sessions for "Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells"
<p>PyMOL sessions with summary of NEF variants docking to IL-6R. Supplementary to "Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells".</p>
Data Analysis for: Coupling Cell Size Regulation and Proliferation Dynamics for C. glutamicum Reveals Cell Division Based on Surface Area
<div>Data and methods of Data Analysis of: Coupling Cell Size Regulation and Proliferation Dynamics of</div> <div>C. glutamicum Reveals Cell Division Based on Surface Area</div> <div> </div> <div>Authors: Cesar Nieto and Zahra Vahdat at University of Delaware (2023)</div> <div>Correspondence: cnieto@udel.edu.</div> <div> </div> <div> </div>
Data for Mechanically-driven Stem Cell Separation in Tissues caused by Proliferating Daughter Cells
<p>Contains animations, data, and source code used for the paper "Mechanically-driven Stem Cell Separation in Tissues caused by Proliferating Daughter Cells" by the same authors. </p> <p><br>This repository contains all the data and analysis scripts to support the manuscript<br>The file structure is as follows:<br>- "analysis" contains all the analysis scripts<br>- "gfx" and "animations" the figures and supporting animations<br>- "1-SCpair", "2-SCtissue", "3-BDsimulation", "4-tissue-stochdiv", "6-inertia-effects" all the source code and data for the respective models.</p>
F I G U R E 4 in Characterisation of stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus
F I G U R E 4 Double Immunofluorescence of brdu plus ki67 in the retina of Misgurnus anguillicaudatus (): (a), (b) brdu labelled cells at 7 months and (c), (d) ki67 labelled cells at 7 months; (e), (f) brdu labelled cells at 1 year and (g), (h) ki67 labelled cells at 1 year. The pigment epithelium showed positive reaction at both ages as well as a few positively reacted cells at the ganglion cell layer at the age of 7 months only. PE, Pigment epithelium layer; g, ganglion cell layer; vl, photoreceptor layer. The total number of fish used was n = 10
F I G U R E 3 in Characterisation of stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus
F I G U R E 3 Double immunofluorescence of brdu plus ki67 in the retina of Misgurnus anguillicaudatus at age of 3 months (). The pigment epithelium layer and the ganglion cell layer showed some proliferative cells. PE, Pigment epithelium layer; vl, photoreceptor layer; IN, inner nuclear layer; ip, inner plexiform layer; ON, outer nuclear layer; OP, outer plexiform layer; g, ganglion cell layer. The total number of fish used was n = 5
F I G U R E 5 in Characterisation of stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus
F I G U R E 5 Immunofluorescence for glial fibrillary acidic protein (GFAP) at the age of 1 month in the eye of Misgurnus anguillicaudatus: (a) glial cells in the periphery of lens (), (b) ganglion cell layer (), (c) inner and outer plexiform layers, photoreceptor layer and pigment epithelium layer (). Immunofluorescence for proliferating cell nuclear antigen (PCNA) in (d) glial cells in the periphery of lens (), (e) ganglion cell layer (), (f) inner and outer plexiform layers, photoreceptor layer and pigment epithelium layer (). L, Lens; PE, pigment epithelium layer; g, ganglion cell layer. The total number of fish used was n = 5
F I G U R E 2 in Characterisation of stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus
F I G U R E 2 The localisation in the retina of Misgurnus anguillicaudatus of (a), (d), (g), (j) bmi1, (b), (e), (h), (k) msi1 and (c), (f), (i), (l) sox2 genes () by using fluorescent in situ hybridisation: (a), (b), (c) 1 month old; (d), (e), (f) age of 7 months; (g), (h), (i) age of 1 year. The visual layer and some few pigment epithelial cells of retina, as well as the lens were the obvious sites for genes expressions. (j), (k), (l) Negative control sense probe. L, Lens; g, ganglion cell layer; vl, visual layer or photoreceptor layer; PE, pigment epithelium. The total number of fish used was n = 15
F I G U R E 1 in Characterisation of stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus
F I G U R E 1 General histological observations of the eye of Misgurnus anguillicaudatus, showing (a) the lens (L) and retina (R) at age 1 month stained with haematoxylin and eosin (H&E); (b) the seven layers of retina at age 1 month stained with H&E (1, ganglion cell layer; 2, inner plexiform layer; 3, inner nuclear layer; 4, outer plexiform layer; 5, outer nuclear layer; 6, photoreceptor layer or visual laye; 7, pigment epithelium); (c) retina at age 1 month stained with Holzer's crystal violet stain (, glial cells); (d) at age 1 year stained with Holzer's crystal violet stain
F I G U R E 6 in Characterisation of stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus
F I G U R E 6 The immunohistochemistry of (a), (b) peroxisome proliferator-activated receptor (PPAR)α and (c), (d) PPARγ in the eye () of Misgurnus anguillicaudatus. The main sites for PPARα expression were ganglion cell layer, inner plexiform, outer plexiform and visual layers. R, Retina; C, cornea; L, lens (L); GCL, ganglion cell layer; IP, inner plexiform IN, inner nuclear; OP, outer plexiform; ON, outer nuclear; vl, photoreceptor layer; PE, pigment epithelium layer (PE). The total number of fish used was n = 5
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