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1,123 results for “Cis”
Fig. 11. Hemibrycon inambari, ANSP 143290 in A review of the Cis-Andean species of Hemibrycon Günther (Teleostei: Characiformes: Characidae: Stevardiinae), with description of two new species
Fig. 11. Hemibrycon inambari, ANSP 143290, paratype, female, 39.2 mm SL. Scanning electron micrograph of right side upper and lower jaws. Scale bar = 1 mm.
Fig. 23. Hemibrycon taeniurus, AMNH 215239 in A review of the Cis-Andean species of Hemibrycon Günther (Teleostei: Characiformes: Characidae: Stevardiinae), with description of two new species
Fig. 23. Hemibrycon taeniurus, AMNH 215239, male, 68.5 mm SL, Island of Trinidad, Trinidad and Tobago.
Fig. 7 in A review of the Cis-Andean species of Hemibrycon Günther (Teleostei: Characiformes: Characidae: Stevardiinae), with description of two new species
Fig. 7. First gill arch showing gill gland. Lateral view of the left side of (a) Hemibrycon helleri, ANSP 180775, (b) Hemibrycon metae, USNM 228563; (c) Hemibrycon huambonicus, USNM 086794; (d) Hemibrycon jelskii, MCP 35022. Scale bars = 1 mm.
Fig. 15. Hemibrycon metae, MCNG 17030 in A review of the Cis-Andean species of Hemibrycon Günther (Teleostei: Characiformes: Characidae: Stevardiinae), with description of two new species
Fig. 15. Hemibrycon metae, MCNG 17030, female, 39.8 mm SL. Scanning electron micrograph of right side upper and lower jaws. Scale bar = 1 mm.
Fig. 7 in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 7. Megalonema orixanthum, holotype, Colombia, Meta State, río Metica, ca. 3 km SE of Hacienda Mozambique. ANSP 187449, 100 mm SL, in a, lateral, b, dorsal and c, ventral view; distal ends of barbels clipped from image c.
Fig. 6. Megalonema amaxanthum, a in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 6. Megalonema amaxanthum, a, lateral view of holotype, CBF 11896, 98 mm SL, b, lateral view of juvenile paratype, ANSP 187452, 39 mm SL, c, dorsal and d, ventral view of holotype; distal ends of barbels clipped from images c and d.
Fig. 5 in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 5. Scatter plots illustrating: a, anal-fin base length relative to standard length, and b, width between posterior nostrils relative to head length, in Megalonema xanthum (squares, n=23), M. amaxanthum (triangles, anal-fin base n=71, width between posterior nostrils n=70), and M. orixanthum (circles, n=41). In t-tests of the residuals from regression, M. amaxanthum proved to have a significantly longer anal-fin base length than M. orixanthum and M. xanthum (p-values <0.0001 for pairwise comparisons), and all three species are significantly different from each other in width between posterior nostrils with increasing relative widths from M. xanthum, M. amaxanthum to M. orixanthum (p-values for pairwise comparisons <0.0001).
Fig. 3 in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 3. Details of supraoccipital processes of a, Megalonema cf. platycephalum ANSP 178450, b, M. xanthum CAS 63674, c, M. amaxanthum, holotype, CBF 11896 (ex FMNH 106769), and d, M. orixanthum ANSP 148180, paratype. Paired lines on each image show the gap between the tip of supraoccipital process and supraneural anteromedial point in or just below skin.
Fig. 2 in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 2. Pelvic fins and basipterygia in Megalonema orixanthum, ANSP 187450, a, ventral view, b, dorsal view, and M. platycephalum, ANSP 189040, c, ventral view, d, dorsal view. alp = anterolateral process; amp = anteromedial process; bp = basal plate; dc = dorsal crest; pp = posterior process; r1-3 = pelvic-fin rays; vc = ventral crest.
Fig. 4. Megalonema xanthum, CAS 63674 in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 4. Megalonema xanthum, CAS 63674, paratype, 118 mm SL, in a, lateral, b, dorsal and c, ventral view.
Fig. 1. a in Two new cis-Andean species of the South American catfish genus Megalonema allied to trans-Andean Megalonema xanthum, with description of a new subgenus (Siluriformes: Pimelodidae)
Fig. 1. a, Weberian complex, post-Weberian vertebrae, basioccipital region and upper bones of shoulder girdle of Megalonema cf. platycephalum, ANSP 178515. b, Weberian complex and gas bladder of M. orixanthum, ANSP 187450. aoc = bony aortic canal; bocc = basioccipital; ccfl = ventral flange of compound centrum; tcom = position of gas bladder tubular commissure posterior to ventral flange; clr = cleithral ring; cpcv = position of bony canal for passage of posterior cardinal vein; gbld = lateral distention of gas bladder; gbtc = transverse commissure of gas bladder; ij5-6 = typical intervertebral joint between c5 and c6; tp4 = ventrally incomplete bony capsules surrounding lateral lobes of gas bladder formed by deeply down-curved 4th transverse processes of Weberian complex; c1, c5, c6, c7 = vertebrae designated by their ordinal numbers.
Mammalian Evolution of Human cis-regulatory Elements and Transcription Factor Binding Sites
<p>Code and data associated with the manuscript entitled "Mammalian Evolution of Human cis-regulatory Elements and Transcription Factor Binding Sites "</p>
Summary statistics of cell-type specific cis-eQTLs in eight brain cell-types
<p>This dataset contains eQTL summary statistics for all SNPs-gene pairs in 8 major brain cell types (within 1MB window surrounding the TSS of each expressed gene). For each cell type, there is one file per chromosome.</p> <p>Column description:</p> <p>1. Gene_id</p> <p>2. SNP_id</p> <p>3. Distance to TSS</p> <p>4. Nominal p-value</p> <p>5. Beta</p> <p>In addition, a file contains the SNP positions (snp_pos.txt) and tested allele.</p> <p>Update February 2023: The summary statistics from our 'tissue-like' analysis were added (pb[1-22].gz). These file contain eQTL summary statistics after aggregating all reads from all nuclei for each individual (instead of per cell type).</p>
Data for: Induction of C4 genes during de-etiolation of Gynandropsis gynandra evolved through changes in cis allowing integration into ancestral C3 gene regulatory networks
<p>C4 photosynthesis has evolved repeatedly and in doing so repurposed existing enzymes to drive a carbon pump that limits the oxygenation reaction of RuBisCO. C4 proteins accumulate to levels matching those of the photosynthetic apparatus, and to allow this gene expression must be modified over evolutionary time. To better understand this rewiring of gene expression we undertook RNA-SEQ and <span>DNaseI</span>-SEQ on de-etiolating seedlings of C4 <em>Gynandropsis gynandra</em> which is evolutionarily proximate to C3 <em>A. thaliana</em>. Changes in chloroplast ultrastructure and C4 gene expression in <em>G. gynandra</em> were coordinated and rapid. C3 and C4 photosynthesis genes showed similar induction patterns, but C4 genes from <em>G. gynandra</em> were more strongly induced than orthologs from <em>A. thaliana</em>. The cistrome of <em>G. gynandra</em> was enriched in TGA, TCP and homeodomain binding sites. Furthermore,<em> in vivo</em> binding data in <em>G. gynandra</em> highlighted TGA and homeodomain as well as light responsive elements such as G- and I-box motifs as being associated with the rapid increase in transcripts derived from C4 genes. Although promoters of <em>PPDK</em> and <em>ASP1</em> from <em>G. gynandra</em> contained distinct light responsive elements, promoters from both <em>A. thaliana</em> and <em>G. gynandra</em> allowed high expression. Deletion analysis of the <em>Ppa6</em> gene from <em>G. gynandra</em> showed that regions containing G- and I-boxes were necessary for high expression. The data support a model in which accumulation of transcripts derived from C4 genes in leaves of <em>G. gynandra</em> is enhanced compared with homologs in <em>A. thaliana</em> because a variety of modifications in <em>cis</em> allowed integration into ancestral transcriptional networks.</p>
Summary statistics of cis-pQTLs for plasma proteins measured using Olink Explore I and II technology in the KARMA cohort.
<p>This data set contains summary statistics for cis regions (+/- 1 Mb around the protein coding gene) for proteins measured by the Olink Explore I and II technology in pre-diagnostic plasma samples from 299 Breast Cancer cases and 299 Breast Cancer free controls from the KARMA cohort. Only proteins detected in at least 25% of individuals are included in this data set. Data set from <a href="https://www.researchsquare.com/article/rs-2749047/v1">Evaluation of Circulating Plasma Proteins in Breast Cancer: A Mendelian Randomization Analysis | Research Square</a></p>
Data from: Subgenome-informed statistical modeling of transcriptomes in 25 common wheat accessions reveals cis- and trans- regulation architectures
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Data for: Induction of C4 genes during de-etiolation of Gynandropsis gynandra evolved through changes in cis allowing integration into ancestral C3 gene regulatory networks
Open the record for dataset details and reuse information.
Data from: Deep mutational scanning of HBV reveals a mechanism for cis preferential reverse transcription
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Data from: Cis-regulatory differences in isoform expression associate with life history strategy variation in Atlantic salmon
<p><span><span><span><span><span><span><span><span><span><span><span><b>A major goal in biology is to understand how evolution shapes variation in individual life histories. Genome-wide association studies have been successful in uncovering genome regions linked with traits underlying life history variation in a range of species. However, lack of functional studies of the discovered genotype-phenotype associations severely restrains our understanding how alternative life history traits evolved and are mediated at the molecular level. Here, we report a <i>cis</i>-regulatory mechanism whereby expression of alternative isoforms of the transcription co-factor <i>vestigial-like 3</i> (<i>vgll3</i>) associate with variation in a key life history trait, age at maturity, in Atlantic salmon (<i>Salmo salar</i>). Using a common-garden experiment, we first show that <i>vgll3 </i>genotype associates with puberty timing in one-year-old salmon males. By way of temporal sampling of <i>vgll3 </i>expression in ten tissues across the first year of salmon development, we identify a pubertal transition in <i>vgll3</i> expression where maturation coincided with a 66% reduction in testicular <i>vgll3</i> expression. The <i>late </i>maturation allele was not only associated with a tendency to delay puberty, but also with expression of a rare transcript isoform of <i>vgll3</i> pre-puberty. By comparing absolute <i>vgll3 </i>mRNA copies in heterozygotes we show that the expression difference between the <i>early</i>and <i>late</i> maturity alleles is largely <i>cis</i>-regulatory. We propose a model whereby expression of a rare isoform from the <i>late </i>allele shifts the liability of its carriers towards delaying puberty. These results exemplify the potential importance of regulatory differences as a mechanism for the evolution of life history traits.</b></span></span></span></span></span></span></span></span></span></span></span></p>
Improved multi-ancestry fine-mapping identifies cis-regulatory variants underlying molecular traits and disease risk
<p>sushie.molqtl.weights.tar.gz contains ancestry-specific eQTL and pQTL weights trained on mRNA and protein levels measured in American European, American African, and American Hispanic ancestries from TOPMed-MESA and GENOA studies. Column “a1” is the counting allele.</p> <p>mesa.*.fusion.tar.gz contains the weights in FUSION format.</p> <p>sushie_real_data_results.tar.gz contains all the real data analyzed in the sushie project.</p> <p>sushie_sim_data_results.tar.gz contains all the sim data analyzed in the sushie project.</p> <p>sushie_analysis_codes.tar.gz contains all the codes and scripts to generate and analyze these data.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.