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157
datasets available to search
ShareScore release 0.9.0
Dataset results
157 results for “Dot1l”
The histone-methyltransferase DOT1L cooperates with LSD1 to control cell division in blast-phase MPN [RNA-seq]
GEO Series GSE300512. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.
DOT1L inhibition blocks multiple myeloma cell proliferation through suppressing IRF4-MYC signaling
GEO Series GSE108661. Homo sapiens. 12 samples. Type: Expression profiling by array.
The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Human RNA-seq]
GEO Series GSE76747. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Combined inhibition of histone methyltransferases EZH2 and DOT1L is an effective therapy for neuroblastoma
GEO Series GSE281811. Homo sapiens. 16 samples. Type: Expression profiling by array.
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation (ATAC-seq)
GEO Series GSE117862. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA-seq analysis of Luciferase control-infected and DOT1L shRNA-infected primary cortical neurons.
GEO Series GSE272883. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Mll1 ko RNA-seq]
GEO Series GSE76749. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome of murine lumbar spinal cord at E12.5 in control and DOT1L cKO through Wnt1cre2 (B6.Cg-E2f1Tg(Wnt1-cre)2Sor/J, Jackson Laboratory #022501)
GEO Series GSE142188. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement
GEO Series GSE217931. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
DOT1L controls NK cell maturation and lineage integrity [RNA-seq D5]
GEO Series GSE222234. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
DOT1L inhibition reveals a distinct class of enhancers dependent upon H3K79 methylation
GEO Series GSE117865. Homo sapiens. 63 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.
DOT-1.1 (DOT1L) deficiency in C. elegans leads to small RNA-dependent gene activation [mRNA, embryos]
GEO Series GSE223801. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.
The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML
GEO Series GSE76750. Mus musculus; Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
RNA-seq analysis about Dot1l knocked out samples
GEO Series GSE201847. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Novel Inhibitors of the Histone-Methyltransferase DOT1L Show Potent Antileukemic Activity in Patient-derived Xenografts
GEO Series GSE149185. Homo sapiens. 58 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Gene expression data from IMR90 Control, IMR90 HRAS-G12V, IMR90 HRAS-G12V+shDOT1L, IMR90 DOT1L Overexpression
GEO Series GSE156648. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor
GEO Series GSE108694. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition. [RNA-Seq]
GEO Series GSE173574. Homo sapiens; Mus musculus. 84 samples. Type: Expression profiling by high throughput sequencing.
Global gene expression analysis of Dot1l-deficient and control intestinal villus cells in mouse
GEO Series GSE41710. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition. [ChIP-Seq]
GEO Series GSE173599. Homo sapiens. 75 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.