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129
datasets available to search
ShareScore release 0.9.0
Dataset results
129 results for “Gain-of-Function”
EZH2 gain-of-function mutations distort H3K27me3 landscapes and transform transcriptional responses to PRC2 inhibition [RNA-seq]
GEO Series GSE218715. Homo sapiens; Mus musculus. 88 samples. Type: Expression profiling by high throughput sequencing.
Sex-dependent gene expression patterns in control and Rspo1 gain-of-function mouse adrenals
GEO Series GSE178958. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Gain-of-function ENL YEATS domain mutations impede nephrogenesis through gene expression control
GEO Series GSE283435. Mus musculus. 34 samples. Type: Expression profiling by high throughput sequencing; Other.
Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F
GEO Series GSE142338. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Pathogenic DICER1 RNase IIIb Hotspot Mutation Induces 3p-miRNA Gain-of-Function via Argonaute Strand Switch [CLASH]
GEO Series GSE279636. Mus musculus. 6 samples. Type: Other.
EZH2 gain-of-function mutations distort H3K27me3 landscapes and transform transcriptional responses to PRC2 inhibition [ChIP-Seq/Cut&Run-Seq]
GEO Series GSE218716. Homo sapiens; Mus musculus. 156 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Gene expression profiles of adult neural stem cells with loss-of-function and gain-of-function of SIRT1
GEO Series GSE39551. Mus musculus. 8 samples. Type: Expression profiling by array.
Gain-of-function genetic alterations of G9a drive oncogenesis II
GEO Series GSE147427. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Human Germline Heterozygous Gain-of-Function STAT6 Variants Cause Severe Allergic Disease
GEO Series GSE222646. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Gain-of-function ENL YEATS domain mutations impede nephrogenesis through gene expression control [Spatial Transcriptomics]
GEO Series GSE283433. Mus musculus. 2 samples. Type: Other.
Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice (scRNA-Seq)
GEO Series GSE201733. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
GEO Series GSE66543. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice
GEO Series GSE201734. Mus musculus. 114 samples. Type: Expression profiling by high throughput sequencing.
The CD33 short isoform is a gain-of-function variant that enhances Aß1-42 phagocytosis in microglia I
GEO Series GSE172525. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Pathogenic DICER1 RNase IIIb Hotspot Mutation Induces 3p-miRNA Gain-of-Function via Argonaute Strand Switch [RNA-seq]
GEO Series GSE279645. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Mutant p53 R270H induces invasion and metastasis of mouse intestinal tumor organoids through gain-of-function mechanism
GEO Series GSE81441. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Maternal transcriptome in response to expression of a gain-of-function MEK mutant
GEO Series GSE162684. Drosophila melanogaster. 6 samples. Type: Expression profiling by high throughput sequencing.
Gain-of-function ENL YEATS domain mutations impede nephrogenesis through gene expression control [RNA-seq]
GEO Series GSE266256. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Differential squamous cell fates elicited by NRF2 gain-of-function versus KEAP1 loss-of-function
GEO Series GSE255927. Mus musculus. 25 samples. Type: Expression profiling by high throughput sequencing.
Human Germline Heterozygous Gain-of-Function STAT6 Variants Cause Severe Allergic Disease [bulk_RNAseq]
GEO Series GSE215390. Homo. 10 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.