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ShareScore release 0.9.0
Dataset results
59 results for “Heart defects, congenital”
Mortality Among Children With Congenital Heart Defects in Norway
ClinicalTrials.gov study NCT02026557. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Non Syndromic Congenital Heart Defect and Array-CGH in Prenatal Diagnosis
ClinicalTrials.gov study NCT02333097. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Human iPSC-derived heart organoids modeling the etiology of pregestational diabetes induced congenital heart defects
GEO Series GSE201343. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Neurodevelopmental and behavioral defects in congenital heart disease [EMX-cre RNAseq]
GEO Series GSE283526. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Single-cell Transcriptomic Profiling Unveils Cardiac Cell-type Specific Response to Maternal Hyperglycemia Underlying the Risk of Congenital Heart Defects
GEO Series GSE193746. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Critical Congenital Heart Defect (CHD) Outcomes in Children
ClinicalTrials.gov study NCT00208689. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Neurodevelopmental and behavioral defects in congenital heart disease [ChIP-seq]
GEO Series GSE283524. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Title: Neurodevelopmental and behavioral defects in congenital heart disease
GEO Series GSE283523. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects
GEO Series GSE260601. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Human stem cell-derived cardiomyocytes integrate into the heart of monkeys with surgically-created congenital-like cardiac defect
GEO Series GSE234206. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling (ChIP-seq data set)
GEO Series GSE110781. Mus musculus. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling
GEO Series GSE108240. Danio rerio. 6 samples. Type: Expression profiling by high throughput sequencing.
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling
GEO Series GSE110783. Mus musculus. 15 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling (RNA-seq data set)
GEO Series GSE110782. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Prevalence of Congenital Heart Defects in Pregnancies Conceived by Assisted Reproductive Technology: A Cohort Study.
<p>Galdini A, Fesslova VME, Gaeta G, Candiani M, Pozzoni M, Chiarello C, Cavoretto PI. Prevalence of Congenital Heart Defects in Pregnancies Conceived by Assisted Reproductive Technology: A Cohort Study. J Clin Med. 2021 Nov 18;10(22):5363. doi: 10.3390/jcm10225363. PMID: 34830645; PMCID: PMC8621349.</p> <p>Abstract</p> <p><strong>Background and aim of the study: </strong>Pregnancies obtained by assisted reproductive technology (ART) are associated with an increased risk of complications and congenital anomalies, particularly congenital heart defects (CHDs). Therefore, our aim is to evaluate, retrospectively, the prevalence of CHD in ART pregnancies in our two centers and analyze their characteristics and outcomes.</p> <p><strong>Methods: </strong>Observational study including fetuses conceived by ART referred between June 2011 and September 2020 and undergoing a fetal cardiac ultrasound scan. Cases with genetic, chromosomal abnormalities or extracardiac malformations were excluded. Population included 1511 pregnancies, which consisted of 269 twins and 1242 singletons, 547 IVF (in vitro fertilization), 773 ICSI (intracytoplasmic sperm injection) and 191 oocyte donations (OD).</p> <p><strong>Results: </strong>CHDs were found in 29 fetuses, with an overall prevalence of 1.92% (29/1511), 1.85% (23/1242) in singletons and 2.23% in twins (6/269). Thirteen were IVF, eight ICSI and eight OD cases, with a greater risk of CHD after IVF and OD (IVF: 13/29 (44.8%)-one twin; ICSI: 8/29 (27.6%)-three twins); 22 had major and 7 minor defects. Two pregnancies with a hypoplastic left heart were terminated; the majority of live-born cases needed surgery. Three babies died (two post-surgery, one had a late death).</p> <p><strong>Conclusions: </strong>Our data show an increased prevalence of CHD after ART with a heterogeneous spectrum of diagnoses, mainly major defects.</p>
INCLUDE: (Sherman) Genomic Analysis of Congenital Heart Defects and Acute Lymphoblastic Leukemia in Children with Down Syndrome
Namespace hosted on the Kids First DRC FHIR services at fhir.kidsfirstdrc.org
INCLUDE: (Lupo) Genomic Analysis of Congenital Heart Defects and Acute Lymphoblastic Leukemia in Children with Down Syndrome
Namespace hosted on the Kids First DRC FHIR services at fhir.kidsfirstdrc.org
INCLUDE: (PCGC) Genomic Analysis of Congenital Heart Defects and Acute Lymphoblastic Leukemia in Children with Down Syndrome
Namespace hosted on the Kids First DRC FHIR services at fhir.kidsfirstdrc.org
Kids First: Genomic Analysis of Congenital Heart Defects and Acute Lymphoblastic Leukemia in Children with Down Syndrome
Namespace hosted on the Kids First DRC FHIR services at fhir.kidsfirstdrc.org
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.