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849 results for “Lactation”
DHA Supplementation for Lactating Mothers
ClinicalTrials.gov study NCT01732874. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Establishing the Vitamin D Requirements During Lactation
ClinicalTrials.gov study NCT00412074. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Does Intravenous Lactated Ringer Solution Raise Measured Serum Lactate?
ClinicalTrials.gov study NCT02950753. IPD Sharing: NO. Countries: 1. Publications: 8.
Data from: Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies
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Data from: Ruminal planktonic, weakly, and tightly feed-adhered bacterial community as affected by two <em>Trichoderma reesei</em> enzyme preparations fed to lactating cattle
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Kisspeptin photometry recordings during pregnancy and lactation
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Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
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Data from: Effects of a second iron dextran injection administered to piglets during lactation on differential gene expression in liver and duodenum at weaning
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Identification of signaling networks associated with lactate modulation of macrophages and dendritic cells
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The biology of prolonged lactation in wild Macaca sinica: Interbirth intervals, maternal depletion, infant mortality
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Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection
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Bacterial composition of the human milk microbiome across lactation
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Data from: lactation at hot temperature: a test of heat dissipation limitation in mice divergently selected for BMR
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The association of lactation duration with visceral and pericardial fat volumes in parous women: 25-year follow-up in the CARDIA study
<p><strong>Background</strong>: Lactation is associated with lower risks for diabetes and cardiovascular disease (CVD) in women. Organ-related adiposity, which plays a significant role in the development of cardiometabolic diseases, could help explain this observation. Therefore, we evaluated the longitudinal association of lactation duration with visceral and pericardial fat volumes in women.</p> <p><strong>Methods</strong>: Data were obtained from 910 women enrolled in the Coronary Artery Risk Development in Young Adults (CARDIA) study (1985-86) without diabetes prior to pregnancy who had ≥1 birth during 25 years of follow-up and had visceral (VAT) and pericardial adipose tissue (PAT) measured from computed tomographic scans in 2010-2011. Cumulative lactation duration across all births since baseline was calculated from self-reports collected at periodic exams.</p> <p><strong>Results</strong>: At baseline, the average age of women (48% black, 52% white) was 24 ± 3.7 years. After controlling for baseline age, race, smoking status, body mass index, fasting glucose, family history of diabetes, fat intake, total cholesterol, physical activity and follow-up covariates (parity, gestational diabetes), the mean fat volumes across categories of lactation (none (n=221), 1 to 5 months (n=306), 6 to 11 months (n=210), and ≥12 months (n=173)) were 122.0, 113.7 105.0, and 110.1 cm3 for VAT and 52.2, 46.7, 44.5 and 43.4 cm3 for PAT, respectively. No race differences were detected. Changes in body weight from the first post-baseline birth to the end of follow-up mediated 21% and 18% of the associations of lactation with VAT and PAT, respectively.</p> <p><strong>Conclusions</strong>: In this prospective study, longer cumulative lactation duration was associated with lower VAT and PAT volumes, with weight gain partially mediating these associations.</p>
Gregariousness, foraging effort, and social interactions in lactating bonobos and chimpanzees
<p>Fission-fusion dynamics have evolved in a broad range of animal taxa and are thought to allow individuals to mitigate feeding competition. While this is the principal benefit of fission-fusion, few studies have evaluated its costs. We compared gregariousness, foraging budgets, and social budgets between lactating bonobos and chimpanzees from wild populations to evaluate such costs. Both species exhibit fission-fusion dynamics, but chimpanzees, particularly in East African populations, appear to experience higher feeding competition than bonobos. We expected lactating chimpanzees to be less gregarious than lactating bonobos; reduced gregariousness should allow lactating chimpanzees to mitigate costs of higher feeding competition without requiring more foraging effort. However, we expected the reduced gregariousness of lactating chimpanzees to limit their time available for affiliative social interactions. Using long-term data from LuiKotale bonobos and Gombe chimpanzees, we found that lactating chimpanzees were indeed less gregarious than lactating bonobos while feeding and travel time did not differ between species. Contrary to our predictions, lactating females did not differ in social interaction time, and lactating chimpanzees spent proportionately more time interacting with individuals other than their immature offspring. Our results indicate that lactating chimpanzees can maintain social budgets comparable to lactating bonobos despite reduced gregariousness and without incurring additional foraging costs. We discuss potential explanations for why lactating bonobos are more gregarious.</p>
Data from: Lactation and resource limitation affect stress responses, thyroid hormones, immune function and antioxidant capacity of sea otters (Enhydra lutris)
1. Lactation is the most energetically demanding stage of reproduction in female mammals. Increased energetic allocation toward current reproduction may result in fitness costs, though the mechanisms underlying these trade-offs are not well understood. Trade-offs during lactation may include reduced energetic allocation to cellular maintenance, immune response and survival, and may be influenced by resource limitation. 2. As the smallest marine mammal, sea otters (Enhydra lutris) have the highest mass-specific metabolic rate necessitating substantial energetic requirements for survival. To provide the increased energy needed for lactation, female sea otters significantly increase foraging effort, especially during late-lactation. Caloric insufficiency during lactation is reflected in the high numbers of maternal deaths due to End-Lactation Syndrome in the California subpopulation. 3. We investigated the effects of lactation and resource limitation on maternal stress responses, metabolic regulation, immune function and antioxidant capacity in two subspecies of wild sea otters (northern: E. l. nereis and southern: E. l. kenyoni) within the California, Washington and Alaska subpopulations. 4. Lactation and resource limitation were associated with reduced glucocorticoid responses to acute capture stress. Corticosterone release was lower in lactating otters. Cortisol release was lower under resource limitation and suppression during lactation was only evident under resource limitation. Lactation and resource limitation were associated with alterations in thyroid hormones. Immune responses and total antioxidant capacity were not reduced by lactation or resource limitation. Southern sea otters exhibited higher concentrations of antioxidants, immunoglobulins and thyroid hormones than northern sea otters. 5. These data provide evidence for allocation trade-offs during reproduction and in response to nutrient limitation but suggest self-maintenance of immune function and antioxidant defenses despite energetic constraints. Income-breeding strategists may be especially vulnerable to the consequences of stress and modulation of thyroid function when food resources are insufficient to support successful reproduction and may come at a cost to survival, and thereby influence population trends.
Impact of Probiotic Veillonella atypica FB0054 Supplementation on Anaerobic Capacity and Lactate Changes: A Randomized, Crossover Pilot
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Ectopic expression of murine CD163 enables cell-culture isolation of lactate dehydrogenase-elevating (LDV) virus 63 years after its discovery
<p><span>Arteriviruses are RNA viruses related to coronaviruses but have not yet been associated with human infection. A murine arterivirus (lactate dehydrogenase-elevating virus, LDV) was first described in 1960 and quickly became a promising model for understanding immune failure due to its unique ability to persist in immunocompetent adult mice. However, inability to culture LDV <em>in vitro</em> ultimately limited this system. Here, we demonstrate that the macrophage marker CD163 is essential for LDV infection. Expression of the murine homolog (mCD163) in otherwise mCD163-negative cell lines from mice and nonhuman primates enables productive LDV infection, creating the first immortalized cell-culture system. We also show that mCD163-knockout mice are completely resistant to LDV infection. These findings advance LDV as a model of arterivirus infection viral persistence and add to a growing body of literature suggesting that CD163 utilization is a broad feature of arteriviruses.</span></p>
Normal Saline versus Lactated Ringer's Solution: Effects on Organ Function and Inflammatory Responses in Heat Stroke in Rat
<p>The data set includes the data generated during the experiment, including vital signs, test indicators, etc. The image file includes the expression of inflammasome proteins measured using WB.</p>
Capturing alterations of intracellular-extracellular lactate distribution in the brain using diffusion-weighted MR spectroscopy in vivo
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.