Find research datasets worth reusing

opencc-by-4.0Jun 2021View details →

Cyclin-Dependent Kinase-Like 5 (CDKL5); A Target Enabling Package

The protein kinase CDKL5 is best known for harbouring loss of function mutations that cause a variant of Rett syndrome, CDKL5 deficiency disorder, that predisposes to seizures and mental retardation. Recent kinome-wide screening has identified CDKL5 as a therapeutic target to ameliorate acute kidney injury, which is a common complication of hospitalisation that can lead to chronic kidney disease. There are currently no proven treatments. We prepared recombinant proteins for the kinase domains of CDKL1, CDKL2, CDKL3 and CDKL5 and solved the structures of these kinases in complex with identified inhibitors at resolutions from 1.5 to 2.4 Å. Overall, the structures capture the kinases with both active and inactive conformations and provide a model to explain the effects of CDKL5 mutation. An in vitro kinase assay showed the importance of a C-terminal αJ helix for the activity of CDKL2 and CDKL3, but not CDKL1 and CDKL5. Functional analyses of the single orthologue in C. elegans CDKL-1 also suggested that CDKL proteins can limit cilia length, which could potentially contribute to the neurological defects in CDKL5 deficiency syndrome. AST-487 and ASC67 present inhibitors of CDKL5 that could be developed for treating acute kidney injury. However, future work is needed to improve selectivity in this drug development.

opencc-by-4.0Jul 2021View details →

Dataset: Effect of decynium-22 on zebrafish anxiety-like behavior

Data for the research project "Effect of decynium-22 on zebrafish anxiety-like behavior", collected at Laboratório de Neurociências e Comportamento "Frederico Guilherme Graeff", Faculdade de Psicologia, Universidade Federal do Sul e Sudeste do Pará.

opencc-by-4.0Aug 2021View details →

Taste responsiveness and liking of model food samples

This data sheet consisted of children's taste intensity perception and liking to model food samples of grapefruit juice and vegetable broth. In addition, children's responses regarding PROP responsiveness, food familiarity, stated liking, food choice, and neophobia were also reported in this data set.

opencc-by-4.0Feb 2023View details →

Increased impact of heat domes on 2021-like heat extremes in North America under global warming

The key codes and processed data for the paper.

opencc-by-4.0Jan 2023View details →

Ultrathin a-Si:H/Oxide Transparent Solar Cells Exhibiting UV-Blue Selective-Like Absorption

Raw Dataset from which the publication of the article "Ultrathin a-Si:H/Oxide Transparent Solar Cells Exhibiting UV-Blue Selective-Like Absorption" (10.1002/solr.202200928) is derived.

opencc-by-4.0Jun 2023View details →

Prenatal diet programs the transgenerational inheritance of brain macro and microstructure defects, coding for anxiety-like behavior in male rats.

T1-w 3DFLASH Preprocessed MRI images used for wistar rat used for the deformation-based morphological (DBM) model are released. Nifti files are duplicated. DBM used only mnc format.

opencc-by-4.0Sep 2023View details →

Generation of beta-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids

This repository contains single-cell RNA-sequencing data files (raw FASTQ files generated from Illumina HiSeq sequencing) related to the article entitled "Generation of beta-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids" by Lisa Morisseau et al. (2023) published in the Molecular Omics journal (DOI: 10.1039/d3mo00050h).

opencc-by-4.0Oct 2023View details →

GENEA Challenge 2023 Human-Likeness subjective evaluation data

This repository contains human-likeness user-study response data and associated analyses from the GENEA Challenge 2023. The code was written by Gustav Eje Henter and is released under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. The archive contains: * This README.txt file. * A LICENSE.txt file. * A JSON file containing all human-likeness user-study responses included in the analyses. * MATLAB .m files for reproducing the above analyses (both tables and figures). * A folder called "output" that contains all files written by the analysis script, including .mat files with all the results computed by each analysis, as well as files created when compiling the final, pretty-looking pdf figures. * A file output.txt that contains all output written to the MATLAB Command Window when running the analyses. Requirements: * MATLAB and MATLAB Image Processing Toolbox * distinguishable_colors.m by Timothy E. Holy (https://www.mathworks.com/matlabcentral/fileexchange/29702-generate-maximally-perceptually-distinct-colors) * fragmaster by Augustin Martin Domingo and Tilman Vogel (https://ctan.org/pkg/fragmaster), a LaTeX utility This was last tested on 2023-10-08 on MATLAB version 9.10.0.1739362 (R2021a) Update 5, running on macOS version 13.2 build 22D49. To re-generate/reproduce the contents in the "output" folder: 0. Ensure that all requirements are met. 1. Run through the entire analysis script "run_analyses.m". 2. Run the fragmaster command in the "output" folder. Attribution: If you use this material in a scientific publication, please cite our latest paper on the GENEA Challenge 2023. At the time of writing (2023-10-08) this is our ACM ICMI 2023 paper. You can use the following BibTeX code to cite that work: @inproceedings{kucherenko2023genea,   author={Kucherenko, Taras and Nagy, Rajmund and Yoon, Youngwoo and Woo, Jieyeon and Nikolov, Teodor and Tsakov, Mihail and Henter, Gustav Eje},   title={The {GENEA} {C}hallenge 2023: {A} large-scale evaluation of gesture generation models in monadic and dyadic settings},   booktitle = {Proceedings of the ACM International Conference on Multimodal Interaction},   publisher = {ACM},   series = {ICMI '23},   year={2023} } To find more GENEA Challenge 2023 material on the web, please see: * https://svito-zar.github.io/GENEAchallenge2023/ * https://genea-workshop.github.io/2023/challenge/ If you have any questions or comments, please contact: * Gustav Eje Henter <ghe@kth.se> * The GENEA Challenge organisers <genea-challenge@googlegroups.com>

opencc-by-4.0Feb 2020View details →

Artifact for the EASE 2020 Paper: How Can I Contribute? A Qualitative Analysis of Community Websites of 25 Unix-Like Distributions

Artifact for the EASE 2020 Paper: How Can I Contribute? A Qualitative Analysis of Community Websites of 25 Unix-Like Distributions Jacob Krüger, Sebastian Nielebock, Robert Heumüller   Please refer to the readme for more details

FIG. 15 in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 15. — Upper molar proportions in Euungulata, "Condylarthra", SANUs, and the kollpaniines from Tiupampa described here. Molar proportions are plotted in the developmental 'morphospace' (Kavanagh et al. 2007; Polly 2007) where the white region is consistent with the IC model; the broken line is the relationship predicted for lower molar of murine rodents (see Material and methods and Table 8). Abbreviations: Kalith., Kalitherium.

FIG. 11 in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 11. — Pucanodus gagnieri: partial right mandible with m2-3 (MHNC 13869): A, stereophotograph of occlusal view; B, the same in labial view. Scale bar: 5 mm.

FIG. 4 in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 4. — Molinodus suarezi: partial maxilla (MHNC 13870) with incomplete M1-2 and complete M3. Stereophotograph of occusal view. Scale bar: 5 mm.

FIG. 7 in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 7. — Simoclaenus sylvaticus: partial right mandible with alveolus of p1, root of p2-3, p4 and m1 (MHNC 13872): A, stereophotographs of occlusal view; B, the same in lateral view; C, the same in medial view. Scale bar: 5 mm.

FIG. 2 in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 2. — Partial left mandible of Molinodus suarezi (MHNC 13867) bearing p3-m3: A, stereophotographs of the occlusal view; B, lingual view; C, labial view. Scale bar: 5 mm.

FIG. 13. — A, B in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 13. — A, B, Lamegoia conodonta; C, didolodontidae indet.; A, occlusal view of a left m2 of Lamegoia conodonta (cast of holotype MNRJ 1463-V); B, occlusal view of a right M2 (reversed) of Lamegoia conodonta (cast of MNRJ 1465-V); C, occlusal view of a left M2 (cast of MNRJ 1464-V) of and undetermined didolodont (referred by Paula Couto [1952a] to L. conodonta). Scale bar: 5 mm.

FIG. 5 in New remains of kollpaniine "condylarths" (Panameriungulata) from the early Palaeocene of Bolivia shed light on hypocone origins and molar proportions among ungulate-like placentals

FIG. 5. — Molinodus suarezi: partial maxilla (MHNC 13870): A, occlusal view; B, lingual view. Scale bar: 5 mm.

opencc-by-4.0Jun 2018View details →

Fig. 2 in Larval morphology of Yateberosus, a New Caledonian endemic subgenus of Laccobius (Coleoptera: Hydrophilidae), with notes on 'Berosus - like' larvae in Hydrophiloidea

Fig. 2. Head morphology of the third instar larva of Laccobius (Yateberosus) sp. A – head in dorsal view; B – head in ventral view; C – detail of clypeolabrum in dorsal view. Chaetotaxy omitted in A–B.

opencc-by-4.0Jul 2009View details →

Figures 33-36. Halodromus patellidens from Aden. 33-34 in The Ebo-like running crab spiders in the Old World (Araneae, Philodromidae)

Figures 33-36. Halodromus patellidens from Aden. 33-34 Left male palp (33 ventral, 34 retrolateral) 35 Epigyne, ventral 36 Vulva, dorsal. Scale line = 0.1 mm.

opencc-by-4.0Jul 2009View details →

Figures 29-32. Halodromus patellaris from Monastir. 29-30 in The Ebo-like running crab spiders in the Old World (Araneae, Philodromidae)

Figures 29-32. Halodromus patellaris from Monastir. 29-30 Left male palp (29 ventral, 30 retrolateral) 31 Epigyne, ventral 32 Vulva, dorsal. Scale line = 0.1 mm.