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1,049 results for “Pseudomonas”
Pseudomonas protegens BIGb0404
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas protegens BIGb0404, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas sp. MYb60
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas sp. MYb60, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas putida JUb85
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas putida JUb85, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas_E nabeulensis MYb114
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas_E nabeulensis MYb114, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas_B oryzihabitans JUb52
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas_B oryzihabitans JUb52, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas lurida MYb17
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas lurida MYb17, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas_E sp013386585 BIGb0164
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas_E sp013386585 BIGb0164, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas_E protegens BIGb0176
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas_E protegens BIGb0176, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas_E helleri BIGb0222
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas_E helleri BIGb0222, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
Pseudomonas_E fluorescens_BV MYb184
This is one of the Wormbiome database archive files.<br>This entry includes all the genome annotation files related to Pseudomonas_E fluorescens_BV MYb184, a\(n\) Gammaproteobacteria.<br>The Wormbiome collection is an online database dedicated to centralizing all the information related to bacteria associated with C. elegans. More information on <a href="https://bitbucket.org/the-samuel-lab/wbm_scripts/src/master/DOCS/Annotations_output.md" target="_blank" rel="noopener noreferrer">the documentation page</a>.<br><br>
The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures
<p><span>The prevalence of antibiotic-resistant pathogens has become a major threat to public health, requiring swift initiatives for discovering new strategies to control bacterial infections. Hence, antibiotic stewardship and rapid diagnostics, but also the development, and prudent use, of novel effective antimicrobial agents are paramount. Ideally, these agents should be less likely to select for resistance in pathogens than currently available conventional antimicrobials. The usage of antimicrobial Peptides (AMPs), key components of the innate immune response, and combination therapies, have been proposed as strategies to diminish the emergence of resistance.</span></p> <p><span>Herein, we investigated whether newly developed random antimicrobial peptide mixtures (RPMs) can significantly reduce the risk of resistance evolution <em>in vitro</em> to that of single sequence AMPs, using the ESKAPE pathogen <em>Pseudomonas aeruginosa</em> (<em>P. aeruginosa</em>) as a model Gram-negative bacterium. Infections of this pathogen are difficult to treat due the inherent resistance to many drug classes, enhanced by the capacity to</span><span> form biofilms. </span><em><span>P. aeruginosa</span></em><span> was experimentally evolved in the presence of AMPs or RPMs, subsequentially assessing the extent of resistance evolution and cross-resistance/collateral sensitivity between treatments. Furthermore, the fitness costs of resistance on bacterial growth were studied, and whole-genome sequencing used to investigate which mutations could be candidates for causing resistant phenotypes. Lastly, changes in the pharmacodynamics of the evolved bacterial strains were examined.</span></p> <p><span>Our findings suggest that using RPMs bears a much lower risk of resistance evolution compared to AMPs and mostly prevents cross-resistance development to other treatments, while maintaining (or even improving) drug sensitivity. This strengthens the case for using random cocktails of AMPs in favour of single AMPs, against which resistance evolved <em>in vitro</em>, providing an alternative to classic antibiotics worth pursuing.</span></p>
Figure 6 in Blue and red light photoemitters as approach to inhibit Staphylococcus aureus and Pseudomonas aeruginosa growth
Figure 6. Percentage of growth inhibition induced by blue light on bacteria inoculated on saline solution or nutrient rich BHI broth. *Statistically significant difference using Mann-Whitney U test (p <0.05) between blue light exposed S. aureus in saline solution and BHI broth.
Figure 5 in Blue and red light photoemitters as approach to inhibit Staphylococcus aureus and Pseudomonas aeruginosa growth
Figure 5. Effect of blue and red light on S. aureus e P. aeruginosa diluted in BHI nutrient rich medium applied for a period of 3 hours. *Statistically significant difference using Mann-Whitney U test (p <0.05) between blue light exposed and control groups.
Figure 3 in Blue and red light photoemitters as approach to inhibit Staphylococcus aureus and Pseudomonas aeruginosa growth
Figure 3. Determination of the influence of glass or polystyrene plate on the antimicrobial effect of red or blue light in S. aureus and P. aeruginosa cultures. *Statistically significant difference using Mann-Whitney U test (p <0.05) between blue light exposed group and control groups.
Figure 4 in Blue and red light photoemitters as approach to inhibit Staphylococcus aureus and Pseudomonas aeruginosa growth
Figure 4. Effect of blue and red light on S. aureus e P. aeruginosa diluted in saline solution (0.9% NaCl) applied for a period of 3 hours. *Statistically significant difference using Mann-Whitney U test (p <0.05) between blue light exposed group and control groups.
Figure 2 in Blue and red light photoemitters as approach to inhibit Staphylococcus aureus and Pseudomonas aeruginosa growth
Figure 2. Diameter of S.aureus and P. aeruginosa surviving colonies after exposure to blue and red light for 6 hours and incubated for 24 hours (A) and 48 hours (B). *Statistically significant difference using Mann-Whitney U test (p <0.05) for independent samples.
Figure 6 in Effect of calcium on Pseudomonas aeruginasa and Bacillus cereus metabolites
Figure 6. Pyorubin production of P. aeruginosa (●), grown in NB medium under static conditions at 37 °C.
Figure 4. H O in Effect of calcium on Pseudomonas aeruginasa and Bacillus cereus metabolites
Figure 4. H O diameter of B. cereus (○) and P. aeruginosa (●), 2 2 grown in NB medium under static conditions at 37 °C.
Figure 3. Las B in Effect of calcium on Pseudomonas aeruginasa and Bacillus cereus metabolites
Figure 3. Las B activity of B.cereus (○) andP.aeruginosa (●), grown in NB medium under static conditions at 37 °C.
Figure 2 in Effect of calcium on Pseudomonas aeruginasa and Bacillus cereus metabolites
Figure 2. Biofilm levels ofB.cereus (○) and P.aeruginosa (●), grown in NB medium under static conditions at 37 °C.
ScienceDex guides
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