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2,308 results for “REPEAT”
Dataset for Repeated double cross validation applied to the PCA-LDA classification of SERS spectra: a case study with serum samples from hepatocellular carcinoma patients
<p>This dataset contains all the spectra used in the paper "Repeated double cross validation applied to the PCA-LDA classification of SERS spectra: a case study with serum samples from hepatocellular carcinoma patients", plus the R code to import the TXT (ASCII) files into a dataset, preprocess data, set-up and cross validate the PCA-LDA model and generate the figures shown in the paper.</p> <p>Data are available in 2 different formats: </p> <p>- 1 compressed archive ("dataset.zip") containing all the 144 TXT files (1 file = 1 spectrum) </p> <p>- 1 single CSV file (“dataset.csv”) with all the 144 spectra in the form of a table. The data are structured as follow, with each row being 1 spectrum, preceded by metadata: "acquisition_date", "substrate_batch", "class", "sample_code".</p> <p>The code for R is available as a single file "Rcode.R".</p> <p> </p>
Participant Faces from a Repeated Prisoner's Dilemma
<p>The authors (ES and TS) conducted a computerized laboratory experiment in an experimental economics laboratory using a modified Prisoner’s Dilemma known as <em>Friend </em>or <em>Foe </em>(e.g. see List, 2006. <em>The Review of Economics and Statistics</em>, <em>88</em>(3), 463-471). 96 young adults aged 18 to 25 years old (51 men, 45 women) gave permission to be video recorded at intervals throughout the experimental procedure under standardized videographic conditions and for their recordings and experiment data to be made available for later research. All individuals video recorded were students at Chapman University in Orange, CA. We provide a dataset described below based on behavioral game and survey data collected from participants over a computer network, media from video recordings, and media analysis measures.</p> <p><em><strong>Description of Experimental Task:</strong> </em>Participants were provided a printed copy of the instructions (Instructions.pdf) explaining the following experimental procedure. Participants were randomly paired with one other person, with whom they anonymously interacted over a computer network throughout the experimental session. Participants were told that at no time would their or other participants’ true identity or videorecorded images be revealed to participants in the experiment session. Participants were told to expect a minimum of two rounds of game interactions with possibility for more rounds. Each round required the participants to first privately state their (non-binding) intention for the camera, saying either “I intend to Split” or “I intend to Take All” (which we videorecorded, see <em>Media: Videos of Stated Intent</em>), then to choose an interaction strategy (either “Split” or “Take All”). Each round we provided participants the results of their pair’s game interaction on their computer screens. We videorecorded participants discovery, viewing, and reaction to the interaction results (see <em>Media: Videos of Viewed Results</em>). After the last round of interaction, we collected response data using an exit survey.</p> <p><strong><em>Game and Survey Data</em>:</strong> Data includes participants’ stated intent and game behavior for each round, emotional reactions (each on a scale of 1 to 5) self-reported after learning the results of each round (measured with a modified 20 item PANAS), and the following data collected during an exit survey: responses (each on a scale of 0 to 4) to six questions used for scoring the Revised Life Orientation Test (from Scheier et al., 1994. <em>Journal of Personality and Social Psychology, 67</em>, 1063-1078), age, gender, first language, and English language fluency.</p> <p><strong><em>Media:</em></strong> Videos of participants were taken using computer display mounted Logitech C920 1080P HD digital cameras, at computer terminals in individual cubicles. The cameras were aimed at participants who sat against a background of either a gray carpeted cubicle or a brown wall under standardized diffuse lighting conditions. For video recordings in this data set, participants were instructed to wear microphone-earphone headsets, to keep hair away from their face, and to sit upright and look at the computer screen they were facing. Camera-to-head distance was controlled by the cubicle space and chair position, and factory default camera settings were held constant.</p> <p><em>Video of Stated Intent.</em> 204 eight-second videos with audio were taken after an on-screen prompt instructed participants to make a spoken non-binding statement of intent. During this phase, we played grey noise over a public address system that masked ambient sound from beyond the individual cubicle within which the video recording equipment was situated. In combination with well insulated over-ear headphones worn by participants, the grey noise was helpful for preventing interference or leakage of other participants’ statements.</p> <p><em>Video of Viewed Results</em>. 204 eight-second videos with audio were taken that capture the moment of participants discovery, viewing, and reaction to the interaction results. The interaction results appear and remain visible to participants on their computer screens from around 2.5 seconds (no earlier than 2 seconds) into the 8 second videos.</p> <p><em>Thin Slice Video.</em> 204 videos (two to three seconds in length) without audio were trimmed from full <em>Videos of Stated Intent</em>. These thin slice videos capture the 2-3 second interval directly following the concluded stated intent.</p> <p><em>Photograph</em>. 204 photographs (640 x 480 pixel .jpg files, 24 Bit depth) including a participant’s full face were captured from video using the VLC media player (3.0.11) “snapshot” tool.</p> <p><strong><em>Media Analysis Measures:</em></strong></p> <p><em>Stated Intent</em>. The particular statement of intent (either “I intend to Split” or “I intend to Take All”) unambiguously recognized by the authors upon inspection of the sound and appearance of each <em>Video of Stated Intent’s</em> recorded statement, is noted in the attached Media.csv file.</p> <p><em>Skin Coloration in Photographs</em>. Using Adobe Photoshop 2020, skin patches (51 × 51 pixels) were selected from the left and right cheeks of each <em>photograph </em>face image. These cheek areas were selected so that they included only skin surfaces but never the edge of a face, ears, lips, or eyelashes. The light (L*),red (a*), and yellow(b*) values that are relevant to human color perception were then measured by centering a "color sampler tool" in Photoshop that averaged over a 51x51 pixel area the CIELab color space values. L*,a*,b* values for right and left cheeks in <em>Photographs</em> are noted in the attached Media.csv file.</p> <p><em>Facial Width to Height in Photographs</em>: To measure facial width to height ratio (fWHR) in photographs, we used tools in Photoshop 2020: first we rotated the photos as necessary using image rotation so that pupils were levelled horizontally, we record the degree of positive or negative rotation used, then we used the <em>frame tool </em>to measure the upperface “height” distance between the upper edge of upper lip and lower edge of brows and the “width” distance between left and right zygion (byzygomatic width) of face images. These methods are consistent with Carre and McCormick (2008, <em>Proceedings of the Royal Society B</em><em>‐</em><em> Biological Sciences, 275</em>, 2651–2656.) methods for measuring the height of upperface and byzygomatic width of face images. The facial width and height in <em>Photographs</em> are noted in the attached Media.csv file.</p> <p><strong>Data and files: </strong>We provide audio-video and image files of <em>Media </em>along with the open-access .csv files detailed below<em>. </em>The above data is organized by the following three data structures in .csv file format.</p> <p>Fields.csv<strong> </strong>is an open-access file includes <em>Game and Survey Data</em> organized by participants and rounds in the experiment. Fields_codebook.csv is a codebook explaining the column headers and participants’ data in the Fields.csv file.</p> <p>Media.csv is an open-access file that catalogues the names and types of <em>Media </em>files provided and includes <em>Media Analysis Measures</em>. Media_codebook.csv is a codebook explaining column headers and participants’ data in the Media.csv file.</p> <p>MappingFile.csv<strong> </strong>is a restricted file linking the participant data in the Fields.csv and Media.csv files. Please contact the authors for this access to this key at <a href="http://doi.org/10.5281/zenodo.4321814">http://doi.org/10.5281/zenodo.4321814</a> if you plan to work at the intersection of these data or replicate published work based on these data.</p> <p>Instructions.pdf is the instructions document provided to all participants in the experiment from which the above data was collected.</p>
Data from: Natural selection and repeated patterns of molecular evolution following allopatric divergence
Background: Geographic speciation is a major force in generating biodiversity. However, how genomes diverge over time after geographic isolation has halted gene flow has remained unclear. We examine genome-wide divergence of putatively single-copy orthologous genes (POGs) from transcriptomes in 20 allopatric species/variety pairs from diverse angiosperm clades. Sixteen of these pairs reflect the well-known eastern Asia – eastern North America floristic disjunction; these species have been isolated for different lengths of time, from the Miocene to Pleistocene. Results: Molecular evolutionary analyses revealed that >90% of the genes examined are under purifying selection and <10% are under positive selection, and this pattern was observed for all taxon pairs, despite differences in divergence time. The divergence level at synonymous sites shared by most POGs in each taxon pair predicts the divergence time between the species/varieties. Divergence time estimates were positively correlated with abundance of genes under moderate purifying selection, but negatively correlated with abundance of genes under strong purifying selection. We identified 200 genes under strong positive selection across the species pairs, with 14 shared by 10-15 pairs and one shared by all taxon pairs. An additional 15 loci annotated to biological processes responding to various stimuli were present in 1-3 pairs.Conclusions: Our results suggest a common "most genes conserved–few genes adaptive" genomic architecture for the taxon pairs, which may be a key for maintaining a balance between the ability to conserve ancestral functions and the ability to evolve new features beneficial for new adaptations. As geographic isolation proceeds through time, the evolutionary trajectory of some genes changed from strong purifying selection to more relaxed selection. The allopatric divergence of these taxon pairs involved both neutral and adaptive evolution of functional genes.
PsPM-BAER: Skin conductance fluctuations in a public speaking paradigm with a repeated-measures design
<p>This dataset contains four skin conductance response (SCR) measurements of 60 s duration from each of 40 healthy male university students (18-35 years) who participated in a public speaking anticipatory anxiety paradigm with a repeated-measures factorial design.</p>
Tandem repeat catalog of the human genome generated from long-read assemblies
<p>Allele sequences of polymorphic loci (VCF) and README for all version 2 (2.0 + 2.1) files</p>
Data for SI-Hg D2 validation report for the calibration of elemental mercury gas generators including information on repeatability, reproducibility and uncertainty evaluation at emission and ambient levels extended to the sub ng/m3 level
<p>In deliverable 2 of the SI-Hg project the first validation results of the SI-Hg calibration protocol are reported. Within the SI-Hg project a protocol for the metrological calibration of elemental mercury gas generators used in the field was developed. For the validation the output of two different mercury gas generators was calibrated according to the protocol. As metrological reference standard the primary mercury gas standard from the Van Swinden Laboratory (VSL) was used. The measurements described in the protocol could be performed during the validation and the data was processed using a script to determine the output of the candidate generator and the uncertainty of the mercury concentration. Based on the validation measurements and data processing several improvements for the calibration protocol were identified and were used to improve the calibration protocol. </p><p>In this repository data obtained during the validation is published. The files of the following comparisons between reference generator and candidate generator can be found in this repository:</p><ul><li>VSL vs VSL<ul><li>m1<ul><li>09022022 calibration mercury gas generator VSL vs VSL m1</li><li>VSL_vs_VSL_m1</li></ul></li><li>m2 <ul><li>05072022 calibration mercury gas generator VSL vs VSL m2</li><li>VSL_vs_VSL_m2</li></ul></li><li>m3<ul><li>07072022 calibration mercury gas generator VSL vs VSL m3</li><li>VSL_vs_VSL_m3</li></ul></li></ul></li><li>VSL vs PSA before modification<ul><li>m1<ul><li>15032022 calibration mercury gas generator VSL vs PSA fixed m1</li><li>single_point_VSL_vs_PSA_fixed_m1_4</li><li>single_point_VSL_vs_PSA_fixed_m1_6</li><li>single_point_VSL_vs_PSA_fixed_m1_8</li><li>single_point_VSL_vs_PSA_fixed_m1_12</li></ul></li><li>m2<ul><li>28032022 calibration mercury gas generator VSL vs PSA fixed m2</li><li>single_point_VSL_vs_PSA_fixed_m2_4</li><li>single_point_VSL_vs_PSA_fixed_m2_6</li><li>single_point_VSL_vs_PSA_fixed_m2_8</li><li>single_point_VSL_vs_PSA_fixed_m2_12</li></ul></li><li>m3 <ul><li>06042022 calibration mercury gas generator VSL vs PSA fixed m3</li><li>single_point_VSL_vs_PSA_fixed_m3_4</li><li>single_point_VSL_vs_PSA_fixed_m3_6</li><li>single_point_VSL_vs_PSA_fixed_m3_8</li><li>single_point_VSL_vs_PSA_fixed_m3_12</li></ul></li><li>m4 <ul><li>12042022 calibration mercury gas generator VSL vs PSA fixed m4</li><li>single_point_VSL_vs_PSA_fixed_m4_4</li><li>single_point_VSL_vs_PSA_fixed_m4_6</li><li>single_point_VSL_vs_PSA_fixed_m4_8</li><li>single_point_VSL_vs_PSA_fixed_m4_12</li></ul></li><li>less tubing <ul><li>14042022 calibration mercury gas generator VSL vs PSA fixed less tubing</li><li>single_point_VSL_vs_PSA_fixed_less_tubing</li></ul></li><li>less tubing and air as complementary gas <ul><li>19042022 calibration mercury gas generator VSL vs PSA fixed less tubing in air</li><li>single_point_VSL_vs_PSA_fixed_less_tubing_air</li></ul></li></ul></li><li>VSL vs PSA after modification<ul><li>m1 air as complementary gas <ul><li>Calibration PSA fixed mercury gas generator air m1 20230324</li><li>PSA_fixed_air_m1_9</li><li>PSA_fixed_air_m1_11</li><li>PSA_fixed_air_m1_14</li></ul></li><li>m2 air as complementary gas <ul><li>Calibration PSA fixed mercury gas generator air m2 20230327</li><li>PSA_fixed_air_m2_9</li><li>PSA_fixed_air_m2_11</li><li>PSA_fixed_air_m2_14</li></ul></li><li>m3 air as complementary gas <ul><li>Calibration PSA fixed mercury gas generator air m3 20230329</li><li>PSA_fixed_air_m3_9</li><li>PSA_fixed_air_m3_11</li><li>PSA_fixed_air_m3_14</li></ul></li><li>m4 air as complementary gas <ul><li>Calibration PSA fixed mercury gas generator air m4 20230907</li><li>PSA_fixed_air_m4_9</li><li>PSA_fixed_air_m4_11</li><li>PSA_fixed_air_m4_14</li></ul></li><li>m5 air as complemantary gas <ul><li>Calibration PSA fixed mercury gas generator air m5 20230911</li><li>PSA_fixed_air_m5_9</li><li>PSA_fixed_air_m5_11</li><li>PSA_fixed_air_m5_14</li></ul></li><li>m1 nitrogen (N2) as complementary gas<ul><li>Calibration PSA fixed mercury gas generator nitrogen m1 20230330</li><li>PSA_fixed_N2_m1_9</li><li>PSA_fixed_N2_m1_11</li><li>PSA_fixed_N2_m1_14</li></ul></li><li>m2 N2 as complementary gas <ul><li>Calibration PSA fixed mercury gas generator nitrogen m2 20230331</li><li>PSA_fixed_N2_m2_9</li><li>PSA_fixed_N2_m2_11</li><li>PSA_fixed_N2_m2_14</li></ul></li><li>m3 N2 as complementary gas <ul><li>Calibration PSA fixed mercury gas generator nitrogen m3 20230405</li><li>PSA_fixed_N2_m3_9</li><li>PSA_fixed_N2_m3_11</li><li>PSA_fixed_N2_m3_14</li></ul></li><li>measurement at TUV<ul><li>PSA_Fixed_at_TUV</li></ul></li></ul></li></ul>
lga BGC Domain alignment files for "Repeated horizontal acquisition of lagriamide-producing symbionts in Lagriinae beetles"
<p>Domains from all lga BGCs recovered from beetle metagenomes were aligned to identified conserved regions and determine if domains were potentially inactivated via mutation of deletion of conserved regions or residues. </p>
Short tandem repeat expansions in LRP12 are absent in familial and sporadic amyotrophic lateral sclerosis patients of European ancestry
<p>In patients of Asian ancestry, a heterozygous CGG repeat expansion of >100 units in <i>LRP12</i> is the cause of oculopharyngodistal myopathy type 1 (OPDM1), and has been associated with amyotrophic lateral sclerosis (ALS) when repeat lengths are between 61-100 units, although with unusually long disease duration and without significant upper motor neuron involvement. This study investigated if <i>LRP12</i> CGG tandem repeats were expanded in ALS patients of European ancestry. We screened whole-genome sequencing data from 608 sporadic ALS patients, 35 familial ALS probands, and 4,703 neurologically normal controls for the <i>LRP12</i> CGG expansion using ExpansionHunter v4. All individuals had <i>LRP12 </i>CGG repeat lengths between 3-25 units. Our results suggest that <i>LRP12 </i>CGG repeat expansions may only be present in ALS patients of Asian ancestry with atypical clinical presentations.</p>
Evolution of conditional cooperation in collective-risk social dilemma with repeated group interactions
<p>The question of how cooperation evolves and is sustained over time has been a long-standing and unresolved issue in the fields of evolutionary biology and social sciences. Previous theoretical and experimental research based on the collective-risk social dilemma game has revealed the risk that the failure of collective goals will affect the evolution of cooperation. Considering that in the real world individuals usually adjust their decisions based on environmental factors such as risk intensity and cooperation level, it is still not well understood how such conditional behaviors affect the evolution of cooperation in repeated group interactions scenario from a theoretical perspective. Here, we construct an evolutionary game model with repeated interactions, in which defectors decide whether to cooperate in subsequent rounds of the game based on whether the risk exceeds their tolerance threshold and whether the number of cooperators exceeds the collective goal in the early rounds of the game. We find that the introduction of conditional cooperation strategy can effectively promote the emergence of cooperation, especially when the risk is low. In addition, the risk threshold significantly affects the evolutionary outcomes. Furthermore, our results confirm that a high risk can promote the emergence of cooperation. Importantly, when the risk exceeds the tolerance threshold, timely adjustment of strategies by conditional cooperators is beneficial for maintaining high-level cooperation.</p>
Repeatedly experiencing the McGurk effect induces long-lasting changes in auditory speech perception
<p>In the McGurk effect, presentation of incongruent auditory and visual speech evokes a fusion percept different than either component modality. We show that repeatedly experiencing the McGurk effect for 14 days induces a change in auditory-only speech perception: the auditory component of the McGurk stimulus begins to evoke the fusion percept, even when presented on its own without accompanying visual speech. This perceptual change, termed fusion-induced recalibration (FIR), was talker-specific and syllable-specific and persisted for a year or more in some participants without any additional McGurk exposure. Participants who did not experience the McGurk effect did not experience FIR, showing that recalibration was driven by multisensory prediction error. A causal inference model of speech perception incorporating multisensory cue conflict accurately predicted individual differences in FIR. Just as the McGurk effect demonstrates that visual speech can alter the perception of auditory speech, FIR shows that these alterations can persist for months or years. The ability to induce seemingly permanent changes in auditory speech perception will be useful for studying plasticity in brain networks for language and may provide new strategies for improving language learning.</p>
Data from: Repeated sensitization of mice with microfilariae of Litomosoides sigmodontis induces pulmonary eosinophilia in an IL-33-dependent manner
<p><strong>Background:</strong> Eosinophilia is a hallmark of helminth infections and eosinophils are essential in the protective immune responses against helminths. Nevertheless, the distinct role of eosinophils during parasitic filarial infection, allergy and autoimmune disease-driven pathology is still not sufficiently understood. In this study, we established a mouse model for microfilariae-induced eosinophilic lung disease (ELD), a manifestation caused by eosinophil hyper-responsiveness within the lung.</p> <p><strong>Methods:</strong> Wild-type (WT) BALB/c mice were sensitized with dead microfilariae (MF) of the rodent filarial nematode <em>Litomosoides sigmodontis </em>three times at weekly intervals and subsequently challenged with viable MF to induce ELD. The resulting immune response was compared to non-sensitized WT mice as well as sensitized eosinophil-deficient dblGATA mice using flow cytometry, lung histology and ELISA. Additionally, the impact of IL-33 signaling on ELD development was investigated using the IL-33 antagonist HpARI2.</p> <p><strong>Results:</strong> ELD-induced WT mice displayed an increased type 2 immune response in the lung with increased frequencies of eosinophils, alternatively activated macrophages and group 2 innate lymphoid cells, as well as higher peripheral blood IgE, IL-5 and IL-33 levels in comparison to mice challenged only with viable MF or PBS. ELD mice had an increased MF retention in lung tissue, which was in line with an enhanced MF clearance from peripheral blood. Using eosinophil-deficient dblGATA mice we demonstrate that eosinophils are essentially involved in driving the type 2 immune response and retention of MF in the lung of ELD mice. Furthermore, we demonstrate that IL-33 drives eosinophil activation <em>in vitro</em> and inhibition of IL-33 signaling during ELD induction reduces pulmonary type 2 immune responses, eosinophil activation and alleviates lung lacunarity.</p> <p>In conclusion, we demonstrate that IL-33 signaling is essentially involved in MF-induced ELD development.</p>
Adaptation of Pseudomonas aeruginosa to repeated invasion into a commensal competitor
<p>Sequencing data for pooled isolate samples of <em>Pseudomonas aeruginosa</em> obtained in experimental evolution project "Adaptation of <em>Pseudomonas aeruginosa</em> to repeated invasion into a commensal competitor". To generate sequencing data, the gDNA from 10 isolates for each culture condition was pooled in equimolar ratios and libraries were sequenced using the Illumina NovaSeq6000 platform using a 250 bp paired-end protocol, submitted for x510 depth sequencing. Dataset provides raw sequencing data (untrimmed) for pooled starting culture isolates, monoculture evolved lines, and coculture evolved lines.</p>
FIGURE 8 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 8 Seven Box plot of median (), 25th and 75th percentiles (), range () and outlier () leukocytes counts of whole blood smears from Salmo salar given single (n = 10) or repeated (n = 30) exposure to the anaesthetics MS-222 (80 mg l−1), metomidate (12.5 mg l−1) and AQUI-S (17 mg l−1). (a) lymphocytes; (b) thrombocytes; (c) neutrophils, (d) monocytes. *, P <0.05
FIGURE 7 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 7 Box plot of median (), 25th and 75th percentiles (), range () and outlier () glucose concentrations of plasma from Salmo salar after single (n = 10) or repeat exposure (n = 30) to the anaesthetics MS-222 (80 mg l−1), metomidate (12.5 mg l−1) and AQUI-S (17 mg l−1). No significant differences were found using a Van der Waerden test
FIGURE 4 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 4 Mean (+SE) accumulation of anaesthetics MS-222, metomidate and AQUI-S in muscle tissue of Salmo salar, as detected by liquid chromatography mass spectrometry. Repeated exposure groups were anaesthetized to Stage III Plane 1 at seven timepoints every four days (Figure 1), followed by a lethal dose of anaesthetic at day 28. Single exposure groups were left undisturbed throughout the experiment, until day 28 and then treated with a lethal dose of anaesthetic. No significant differences were found between single and repeated doses of respective anaesthetics () Single, and () Repeated
FIGURE 6 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 6 Mean (+SE) expression of selected genes from Salmo salar head kidney relative to the housekeeping gene elongation factor α (elfα). Head kidney was analysed after a single (n = 10) or repeated exposure (n = 30) to (a) MS-222 (80 mg l−1) () Single, and () Repeat, (b) metomidate (12.5 mg l−1) () Single, and () Repeat and (c) AQUI-S (17 mg l−1) () Single, and () Repeat. Log -transformed data were 10 compared by one-way ANOVA. *P <0.05
FIGURE 3 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 3 Mean epithelial lifting score (Table 1) for Salmo salar gills assessed by histology after repeated or single dose exposures of fish to the anaesthetics MS-222 (80 mg l−1), metomidate (12.5 mg l−1) and AQUI-S (17 mg l−1). Different letters denote significant differences (P <0.05) between groups assessed by ordinal regression analysis
FIGURE 5 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 5 Mean (+SE) relative expression of selected genes in Salmo salar gills. Gene expression level was quantified by real-time PCR, normalized using the housekeeping gene elongation factor α (elfα), and expressed as arbitrary unit where the expression in single exposure is 1. Gills were analysed after a single (n = 10) or repeated exposure (n = 30) to (a) MS-222 (80 mg l−1) () Single, and () Repeat, (b) metomidate (12.5 mg l−1) () Single, and () Repeat and (c) AQUI-S (17 mg l−1) () Single, and () Repeat. Log -transformed data were 10 compared by one-way ANOVA. *P <0.05; **, P <0.01; ***P <0.001
FIGURE 2 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 2 Differential-interference contrast images of Salmo salar gill after dosing with three anaesthetic agents: (a) single and (d) repeat exposure to MS-222 (80 mg l−1); (b) single and (e) repeat exposure to metomidate (12 mg l−1); (c) single and (f) repeat exposure to AQUI-S (17 mg l−1). e, epithelial cell; sl, secondary lamella; p, pillar cell; g, goblet cell; pl, primary lamellae; er, erythrocyte., Area showing evidence of epithelial lifting; S.I., foci of mild subepithelial infiltration. Scale bar 100 μm. Magnification ×400
FIGURE 1 Log2 in Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar
FIGURE 1 Log2 mean (SD, n = 3) repeat-treatment induction times of Salmo salar () to Stage III, Plane 1 anaesthesia with MS-222 (80 mg l−1), metomidate (12.5 mg l−1) and AQUI-S (17 mg l−1). P> 0.05 for each anaesthetic, as assessed by repeated measures ANOVA () MS-222, () Metomidate, and () AQUI-S
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.