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126
datasets available to search
ShareScore release 0.9.0
Dataset results
126 results for “RNA interference”
The interaction of influenza A NS1 and cellular TRBP protein modulates the function of RNA interference machinery
GEO Series GSE189776. Mus musculus; Homo sapiens. 5 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Teosinte Pollen Drive guides maize domestication and evolution by RNA interference [dna_single_pollen]
GEO Series GSE234920. Zea mays subsp. mays x Zea mays subsp. mexicana. 377 samples. Type: Other.
Stereopure phosphoryl guanidine backbone chemistry increases the potency and durability of gene silencing by RNA interference
GEO Series GSE220502. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide CRISPR interference screen identifies long non-coding RNA DARS1-AS1 as a novel regulator of glioblastoma tumorigenesis.
GEO Series GSE213046. Homo sapiens. 28 samples. Type: Other.
Evaluation of non-invasive dsRNA delivery methods for the development of RNA interference in the Asian tiger mosquito Aedes albopictus
<p>The Asian tiger mosquito Aedes albopictusis one of the most invasive species and an efficient vector of<br>several pathogens. RNA interference (RNAi) has been proposed as an alternative method to control<br>mosquito populations by silencing the expression of genes that are essential for their survival. However,<br>the optimal delivery method for dsRNAs to enhance an optimal RNAi remains elusive and comparative<br>studies are lacking. We have, therefore, compared the efficiency of three non-invasive delivery methods to<br>mosquito larvae: soaking, rehydration and nanoparticle ingestion. Each method was tested separately on<br>four genes predicted to code non-essential proteins (i.e. collagenase-like, kynurenine 3-monooxygenaselike, yellow-like and venom serine protease-like) in order to be able to compare the importance of gene<br>knock-down.<br>All tested methods successfully downregulated mosquito gene expression. However, silencing efficiency<br>strongly varies among methods and genes. Silencing (95.1%) was higher for Kynurenine 3-<br>monooxygenase-like with rehydration and nanoparticle ingestion (61.1%). For the Venom serine proteaselike, the most efficient silencing was observed with soaking (74.5%) and rehydration (34%). In contrast,<br>the selected methods are inefficient to silence the other genes. Our findings also indicate that gene copy<br>numbers, transcript sizes and GC content correlate with the silencing efficiency.<br>From our results, rehydration was the most specific and efficient methods to specifically knock-down<br>gene expression in Ae. albopictus larvae. Nevertheless, considering the observed variability of efficiency is<br>gene-dependent, our results also point at the necessity to test and optimize diverse dsRNA delivery<br>approaches to achieve a maximal RNAi efficiency.</p>
RNA interference-independent reprogramming of DNA methylation in Arabidopsis
GEO Series GSE148753. Arabidopsis thaliana. 72 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Comparative analysis of RNA interference and pattern-triggered immunity induced by dsRNA in response to virus infection
GEO Series GSE253964. Nicotiana benthamiana. 12 samples. Type: Expression profiling by high throughput sequencing.
Control of white mold (Sclerotinia sclerotiorum) through plant mediated RNA interference
GEO Series GSE217513. Arabidopsis thaliana. 17 samples. Type: Expression profiling by high throughput sequencing.
Antiviral RNA interference in mammalian cells
GEO Series GSE43153. Mus musculus. 9 samples. Type: Other; Non-coding RNA profiling by high throughput sequencing.
Gene Expression Profiles Induced by RNA interference on NSD1 Δ5Δ7, and NSD1 Δ19–23 isoforms in Fibroblast Cells III.
GEO Series GSE253404. Homo sapiens. 8 samples. Type: Expression profiling by array.
Gene Expression Profiles Induced by RNA interference on NSD1 Δ5Δ7, and NSD1 Δ19–23 isoforms in Fibroblast Cells II.
GEO Series GSE253403. Homo sapiens. 8 samples. Type: Expression profiling by array.
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq]
GEO Series GSE80176. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Systemic RNA interference-defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans
GEO Series GSE205118. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.
In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
GEO Series GSE46307. Mus musculus. 8 samples. Type: Expression profiling by array.
Matrix-anchored Nanoparticles for MMP13 RNA Interference Block Post-Traumatic Osteoarthritis
GEO Series GSE171031. Mus musculus. 48 samples. Type: Expression profiling by array.
Parallel quantitative CRISPR interference in yeast identifies chemical-genetic interactions and new rules for guide RNA design
GEO Series GSE71490. Saccharomyces cerevisiae. 84 samples. Type: Other.
Salicylic acid and RNA interference mediate antiviral immunity of plant stem cells (Previous preprint title: A hormone-activated mobile RNAi pathway defends plant stem cells from virus infection)
GEO Series GSE242499. Arabidopsis thaliana. 8 samples. Type: Expression profiling by high throughput sequencing.
In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
GEO Series GSE46302. Homo sapiens. 24 samples. Type: Expression profiling by array.
Teosinte Pollen Drive guides maize domestication and evolution by RNA interference [iPARE-seq]
GEO Series GSE234922. Zea mays subsp. mays x Zea mays subsp. mexicana. 6 samples. Type: Other.
Teosinte Pollen Drive guides maize domestication and evolution by RNA interference
GEO Series GSE234925. Zea mays subsp. mays x Zea mays subsp. mexicana. 433 samples. Type: Other; Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.